The suggested structure of final demand shock for sectoral labour digital skills

International data seem to confirm that countries with a relative abundancy of highly-skilled labour with digital competences grow faster than others. For this reason, digital competences and skills in general are progressively assuming a central role in labour market policies. In this article, we show the potential of the disaggregated multisectoral analysis with the macro multipliers approach as a tool of economic policy. Such analyses allow identifying a set of endogenous policies in which specific objectives do not clash with growth objectives. The identification and the quantification of the macro multipliers is based on an extended multi-industry, multi-factor and multi-sector model, which accounts for the representation of the income circular flow as in the social accounting matrix (SAM). The SAM constructed for this exercise allows for a proper disaggregation of the labour factor by formal educational attainment, digital competences and gender for the case of Italy

Politiche per l'industria: ridurre o abolire l'Irap?

L’imposta regionale sulle attività produttive (Irap) è oggetto di un ampio dibattito incentrato su alcune ipotesi di riforma relative alla riduzione o alla abolizione di questo strumento di prelievo, percepito dagli operatori come iniquo. L’argomentazione a sostegno di queste tesi si basa sul fatto che una diminuzione del prelievo potrebbe supportare ovvero stimolare il sistema produttivo, soprattutto in termini di competitività. L’analisi delle possibili riforme dell’Irap non dovrebbe trascurare gli effetti indotti dalla distribuzione del reddito, evidenziando quali potrebbero essere i percettori di reddito avvantaggiati e svantaggiati. In questo lavoro si utilizzerà un modello computazionale (CGE), implementato su una SAM (Social Accounting Matrix) che descrive il flusso circolare del reddito, per valutare l’impatto dei possibili scenari di riforma dell’Irap sulla produzione industriale, sul reddito reale, sul livello dei prezzi dei beni e dei fattori primari, sull’occupazione e sul bilancio dello Stato. Infine, in alternativa alla riforma Irap, si prenderà in considerazione l’ipotesi di destinare l’ammontare delle risorse disponibili alla riduzione delle aliquote Ire.Irap,Social Accounting Matrix,CGE,Ire

The occurrence of postoperative vertigo after CI

Background. The incidence of postoperative vertigo after cochlear implantation (CI) varies a lot in the literature. The aim of this work was to investigate both subjective complaints of vertigo before and after cochlear implantation and related it to to the preoperative vestibular function, the surgical procedure and to the position of CI at the postoperative neuroradiological study. Methods. Retrospective cohort study of adult CI series operated by the same surgeon (DZ) over the last 3 years. (N= 107). Sixty-six subjects (38 F; 28 M), aged from 21 to 78 years old were included in the study, lasting 83 CI. The outcomes of the pre-operative vestibular assessment were extracted from the database of the Vestibular Disorders Unit of the tertiary referral University Hospital of Milano from 1992 to 2018 (N=557). Post-operative presence/absence of vestibular disorders was analyzed and related to the preoperative vestibular examination and to the flat-panel computed tomography (FPCT) findings. Results: The patients were divided by age and by the presence of vestibular response of the operated ear measured by videoculography, caloric testing and video-impulse test. Sensorial analysis by static posturography was also included. The incidence of postoperative vertigo was higher in patients > 65 years old (36.3% vs 20.4%, p=0.03). Postoperative vertigo did not result related to the surgical procedure. The results are discussed with the review of the literature. Conclusion: Our results confirm the importance of vestibular testing in CI recipients, in order to better counsel the patient on the foreseeable post-operative course and to identify those patients who will need a vestibular rehabilitation

A New Monte Carlo Algorithm for Protein Folding

We demonstrate that the recently proposed pruned-enriched Rosenbluth method (P. Grassberger, Phys. Rev. E 56 (1997) 3682) leads to extremely efficient algorithms for the folding of simple model proteins. We test them on several models for lattice heteropolymers, and compare to published Monte Carlo studies. In all cases our algorithms are faster than all previous ones, and in several cases we find new minimal energy states. In addition to ground states, our algorithms give estimates for the partition sum at finite temperatures.Comment: 4 pages, Latex incl. 3 eps-figs., submitted to Phys. Rev. Lett., revised version with changes in the tex

Effect of eye lateralization on contralateral suppression of transient evoked otoacoustic emissions

Several studies have previously demonstrated that postural changes modify evoked otoacoustic emission. In order to evaluate a possible interaction between eye muscles and ciliated cells in the inner ear, we studied the effects of eye lateralization on the contralateral suppression of transient evoked otoacoustic emissions (TEOAEs). Thirty-eight normal hearing subjects with TEOAEs were recruited. Their TEAOEs at threshold level were recorded with contralateral suppression (white noise) via straight ahead fixation and right or left lateral fixation. Eye lateralization in the same direction of the white noise significantly decreased the suppression at 4 kHz (p = 0.003). The signal-to-noise ratio in the suppression condition with straight ahead was 1.54 (± 4.610) dB, while the ratio was 3.48 (± 4.631) dB in the suppression condition with gaze toward the white noise. Eye lateralization seems to reduce the contralateral suppression effect of TEOAEs at 4 kHz. However, further studies are necessary to investigate the possible mechanisms of this phenomenon

Modeling study on the validity of a possibly simplified representation of proteins

The folding characteristics of sequences reduced with a possibly simplified representation of five types of residues are shown to be similar to their original ones with the natural set of residues (20 types or 20 letters). The reduced sequences have a good foldability and fold to the same native structure of their optimized original ones. A large ground state gap for the native structure shows the thermodynamic stability of the reduced sequences. The general validity of such a five-letter reduction is further studied via the correlation between the reduced sequences and the original ones. As a comparison, a reduction with two letters is found not to reproduce the native structure of the original sequences due to its homopolymeric features.Comment: 6 pages with 4 figure

Coarse grained description of the protein folding

We consider two- and three-dimensional lattice models of proteins which were characterized previously. We coarse grain their folding dynamics by reducing it to transitions between effective states. We consider two methods of selection of the effective states. The first method is based on the steepest descent mapping of states to underlying local energy minima and the other involves an additional projection to maximally compact conformations. Both methods generate connectivity patterns that allow to distinguish between the good and bad folders. Connectivity graphs corresponding to the folding funnel have few loops and are thus tree-like. The Arrhenius law for the median folding time of a 16-monomer sequence is established and the corresponding barrier is related to easily identifiable kinetic trap states.Comment: REVTeX, 9 pages, 15 EPS figures, to appear in Phys. Rev.

Non-Markovian Configurational Diffusion and Reaction Coordinates for Protein Folding

The non-Markovian nature of polymer motions is accounted for in folding kinetics, using frequency-dependent friction. Folding, like many other problems in the physics of disordered systems, involves barrier crossing on a correlated energy landscape. A variational transition state theory (VTST) that reduces to the usual Bryngelson-Wolynes Kramers approach when the non-Markovian aspects are neglected is used to obtain the rate, without making any assumptions regarding the size of the barrier, or the memory time of the friction. The transformation to collective variables dependent on the dynamics of the system allows the theory to address the controversial issue of what are ``good'' reaction coordinates for folding.Comment: 9 pages RevTeX, 3 eps-figures included, submitted to PR