714 research outputs found

    Psychological Types and Temperaments: A Correlational Study Using the Myers-Briggs Type Indicator and the Temperament Inventory

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    Problem The purpose of this study was to determine whether there is a significant relationship between the construct of psychological types, as measured by the Myers-Briggs Type Indicator (MBTI), and temperaments, as measured by the Temperament Inventory (TI). Method A non-random sample of 113 individuals completed a demographic questionnaire, the MBTI, and the TI. The results of each preference score of the MBTI and the scores on each of the four temperaments from the TI were compared using a canonical correlation analysis. Results There is a significant relationship between the MBTI\u27s psychological types and the TI\u27s temperaments. A preference for extroversion on the MBTI was correlated with a sanguine temperament, while preferences for thinking and judging on the MBTI were correlated with a choleric temperament. Conclusions The constructs of psychological types and temperaments should not be considered to be completely independent

    Initial stage of the 2D-3D transition of a strained SiGe layer on a pit-patterned Si(001) template

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    We investigate the initial stage of the 2D-3D transition of strained Ge layers deposited on pit-patterned Si(001) templates. Within the pits, which assume the shape of inverted, truncated pyramids after optimized growth of a Si buffer layer, the Ge wetting layer develops a complex morphology consisting exclusively of {105} and (001) facets. These results are attributed to a strain-driven step-meandering instability on the facetted side-walls of the pits, and a step-bunching instability at the sharp concave intersections of these facets. Although both instabilities are strain-driven, their coexistence becomes mainly possible by the geometrical restrictions in the pits. It is shown that the morphological transformation of the pit surface into low-energy facets has strong influence on the preferential nucleation of Ge islands at the flat bottom of the pits.Comment: 19 pages, 7 figure

    Non-contact Pressure-based Sleep/Wake Discrimination

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    Concert recording 2018-01-21

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    [Track 1]. Une flȗte soupire (A Sighing Flute) / Mel Bonis -- [Track 2]. Suite en trio for Flute, Violin, and Piano, Op. 59. I. Sérénade [Track 3]. II. Pastorale [Track 4]. III. Scherzo / Mel Bonis -- [Track 5]. Sonata in C-sharp minor for Flute and Piano, Op. 64. I. Andantino con moto [Track 6]. II. Scherzo - Vivace [Track 7]. III. Adagio - Allegro ma non troppo - Adagio [Track 8]. IV. Finale - Moderato / Mel Bonis -- [Track 9]. Scherzo (Final) for Flute and Piano, Op. posth. 187 / Mel Bonis -- [Track 10]. Barcarolle in E-flat Major for Piano, Op. 71 / Mel Bonis -- [Track 11]. Scénes de la forêt (Forest Scenes) for Flute, Horn, and Piano, Op. 123. I. Nocturne [Track 12]. II. A l\u27aube (At Dawn) [Track 13]. III. Invocation [Track 14]. IV. Pour Artémis / Mel Bonis

    Lattice diffusion and surface segregation of B during growth of SiGe heterostructures by molecular beam epitaxy: effect of Ge concentration and biaxial stress

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    Si1-xGex/Si1-yGey/Si(100) heterostructures grown by Molecular Beam Epitaxy (MBE) were used in order to study B surface segregation during growth and B lattice diffusion. Ge concentration and stress effects were separated. Analysis of B segregation during growth shows that: i) for layers in epitaxy on (100)Si), B segregation decreases with increasing Ge concentration, i.e. with increased compressive stress, ii) for unstressed layers, B segregation increases with Ge concentration, iii) at constant Ge concentration, B segregation increases for layers in tension and decreases for layers in compression. The contrasting behaviors observed as a function of Ge concentration in compressively stressed and unstressed layers can be explained by an increase of the equilibrium segregation driving force induced by Ge additions and an increase of near-surface diffusion in compressively stressed layers. Analysis of lattice diffusion shows that: i) in unstressed layers, B lattice diffusion coefficient decreases with increasing Ge concentration, ii) at constant Ge concentration, the diffusion coefficient of B decreases with compressive biaxial stress and increases with tensile biaxial stress, iii) the volume of activation of B diffusion () is positive for biaxial stress while it is negative in the case of hydrostatic pressure. This confirms that under a biaxial stress the activation volume is reduced to the relaxation volume

    Concert recording 2018-10-18a

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    [Track 1]. Tangoescente / Adriana Verdié -- [Track 2]. Veni variationes (commissioned work) / Robert Mueller -- [Track 3]. Dos tropicos! / Matthieu Lussier -- [Track 4]. Wind quintet no. 3. 3. Finale giocoso / Miguel del Águila [Track 5]. Habanera from Aires Topicales [Track 6]. Contradanza from Aires Topicales [Track 7]. La fleur de Cayenne / Paquito D\u27Rivera

    Anti-atherogenic modification of serum lipoprotein function in patients with rheumatoid arthritis after tocilizumab treatment, a pilot study

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    Lipid metabolism derangement contributes to increased cardiovascular risk in Rheumatoid Arthritis (RA). It is still debated whether and how tocilizumab, an interleukin-6 receptor inhibitor used in active RA, impacts cardiovascular risk. We studied the effect of tocilizumab on the regulation of macrophage cholesterol homeostasis, measuring patient serum ability to respectively load (cholesterol loading capacity, CLC) and discharge (cholesterol efflux capacity, CEC) cells with cholesterol. Patients with RA (n = 8) were studied before and after 4 and 12 weeks of tocilizumab treatment. CLC was measured by a fluorimetric assay of intracellular cholesterol content in human macrophages and CEC was measured for the three main pathways, mediated by the transporters Scavenger Receptor class B-type I (SR-BI), ATP binding cassette-G1 (ABCG1) and-A1 (ABCA1) in specific cell models. After 12 weeks of tocilizumab treatment, serum LDL cholesterol levels were increased, while CLC was reduced. HDL cholesterol levels were unchanged, but CEC was significantly ameliorated for the SR-BI and ABCG1 pathways with respect to baseline. Tocilizumab reduces LDL pro-atherogenic potential despite increasing their serum levels and increases HDL protective activity in RA. The data of our pilot study suggest that tocilizumab regulates lipoprotein function in selected patient populations and lay the groundwork for future larger studies

    Iron metabolism at the interface between host and pathogen: From nutritional immunity to antibacterial development

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    Nutritional immunity is a form of innate immunity widespread in both vertebrates and invertebrates. The term refers to a rich repertoire of mechanisms set up by the host to inhibit bacterial proliferation by sequestering trace minerals (mainly iron, but also zinc and manganese). This strategy, selected by evolution, represents an effective front-line defense against pathogens and has thus inspired the exploitation of iron restriction in the development of innovative antimicrobials or enhancers of antimicrobial therapy. This review focuses on the mechanisms of nutritional immunity, the strategies adopted by opportunistic human pathogen Staphylococcus aureus to circumvent it, and the impact of deletion mutants on the fitness, infectivity, and persistence inside the host. This information finally converges in an overview of the current development of inhibitors targeting the different stages of iron uptake, an as-yet unexploited target in the field of antistaphylococcal drug discovery

    Iron metabolism at the interface between host and pathogen: From nutritional immunity to antibacterial development

    Get PDF
    Nutritional immunity is a form of innate immunity widespread in both vertebrates and invertebrates. The term refers to a rich repertoire of mechanisms set up by the host to inhibit bacterial proliferation by sequestering trace minerals (mainly iron, but also zinc and manganese). This strategy, selected by evolution, represents an effective front-line defense against pathogens and has thus inspired the exploitation of iron restriction in the development of innovative antimicrobials or enhancers of antimicrobial therapy. This review focuses on the mechanisms of nutritional immunity, the strategies adopted by opportunistic human pathogen Staphylococcus aureus to circumvent it, and the impact of deletion mutants on the fitness, infectivity, and persistence inside the host. This information finally converges in an overview of the current development of inhibitors targeting the different stages of iron uptake, an as-yet unexploited target in the field of antistaphylococcal drug discovery
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