52 research outputs found

    Reduced invariants from cuspidal maps

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    We consider genus one enumerative invariants arising from the Smyth-Viscardi moduli space of stable maps from curves with nodes and cusps. We prove that these invariants are equal to the reduced genus one invariants of the quintic threefold, providing a modular interpretation of the latter

    Virtual classes for the working mathematician

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    This note is intended to be a friendly introduction to virtual classes. We review virtual classes and we give a number of properties and applications. We also include a new virtual push-forward theorem and many computations of virtual classes in simple examples

    Three embeddings of the Klein simple group into the Cremona group of rank three

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    We study the action of the Klein simple group G consisting of 168 elements on two rational threefolds: the three-dimensional projective space and a smooth Fano threefold X of anticanonical degree 22 and index 1. We show that the Cremona group of rank three has at least three non-conjugate subgroups isomorphic to G. As a by-product, we prove that X admits a Kahler-Einstein metric, and we construct a smooth polarized K3 surface of degree 22 with an action of the group G.Comment: 43 page

    Assessment of the technological performance of some Saccharomyces and non-Saccharomyces indigenous yeast strains

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    The study aimed to assess the technological potential of four indigenous Saccharomyces cerevisiae strains (S. cer. 4.1.11, S. cer. 4.3, S. cer. 4.6 and S. cer. 4.10), as possible sources for starter cultures. The experiments were carried out at micropilot level on the natural must of 'Fetească albă' cultivar. The evaluation of the yeasts was carried out according to the chemical parameters and volatile compounds analysed in the obtained wines compared to the wine obtained with a commercial starter culture (CSC). The values of the main physico-chemical parameters analyzed in the obtained wines were similar to those determined in the control wine. The average values of the volatile compounds with positive impact on the wine aroma ranged within the interval 177.46 - 217.81 mg/L, a higher value compared to the control wine, respectively 166.33 mg/L. The use of the indigenous strain Torulospora delbrueckii (T.d 10) in association with the strains S. cer. 4.1.11 or S. cer. 4.10 led to an increase of 12.56%, respectively 8.30% in glycerol concentrations, as well as an increase of 11.94% to 14.49% in the average concentration of volatile compounds. Harnessing the oenological potential of the yeasts tested in sequential fermentations proved dependent on the time allowed for the development of the strain T.d 10, namely 24 and 48 hours, as well as on the yeasts used. Thus, in the wines obtained by the association T.d 10/ S. cer. 4.10, in which the development of the culture T.d 10 was carried out for 48 hours, we noticed an increase of 12.52% and, respectively 32.95%, in the average of volatile compounds, compared to the monoculture wine for the same S. cer. 4.10 strain and to the control wine (CSC)

    Quality of life measurement in alopecia areata. Position statement of the European Academy of Dermatology and Venereology Task Force on Quality of Life and Patient Oriented Outcomes

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    New treatment options may lead to an increased interest in using reliable and sensitive instruments to assess health-related quality of life in people with alopecia areata (AA). The purpose of this paper is to present current knowledge about quality of life assessment in AA. The dermatology-specific Dermatology Life Quality Index (DLQI) was the most widely reported health-related quality of life instrument used in AA. Three AA-specific (Alopecia Areata Symptom Impact Scale, Alopecia Areata Quality of Life Index and Alopecia Areata Patients'' Quality of Life) and three hair disease-specific instruments (Hairdex, Scalpdex and ‘hair-specific Skindex-29’) were identified with a range of content and validation characteristics: there is little evidence yet of the actual use of these measures in AA. Scalpdex is the best-validated hair disease-specific instrument. Further extensive validation is needed for all of the AA-specific instruments. The European Academy of Dermatology and Venereology Task Force on Quality of Life and Patient Oriented Outcomes recommends the use of the dermatology-specific DLQI questionnaire, hair disease-specific Scalpdex and the alopecia areata-specific instruments the Alopecia Areata Symptom Impact Scale or Alopecia Areata Quality of Life Index, despite the limited experience of their use. We hope that new treatment methods will be able to improve both clinical signs and health-related quality of life in patients with AA. In order to assess the outcomes of trials on these new treatment methods, it would be helpful when further development and validation of AA-specific instruments is being encouraged and also conducted. © 2021 European Academy of Dermatology and Venereology

    Quality of life measurement in alopecia areata. Position statement of the European Academy of Dermatology and Venereology Task Force on Quality of Life and Patient Oriented Outcomes

    Get PDF
    New treatment options may lead to an increased interest in using reliable and sensitive instruments to assess health-related quality of life in people with alopecia areata (AA). The purpose of this paper is to present current knowledge about quality of life assessment in AA. The dermatology-specific Dermatology Life Quality Index (DLQI) was the most widely reported health-related quality of life instrument used in AA. Three AA-specific (Alopecia Areata Symptom Impact Scale, Alopecia Areata Quality of Life Index and Alopecia Areata Patients' Quality of Life) and three hair disease-specific instruments (Hairdex, Scalpdex and ‘hair-specific Skindex-29’) were identified with a range of content and validation characteristics: there is little evidence yet of the actual use of these measures in AA. Scalpdex is the best-validated hair disease-specific instrument. Further extensive validation is needed for all of the AA-specific instruments. The European Academy of Dermatology and Venereology Task Force on Quality of Life and Patient Oriented Outcomes recommends the use of the dermatology-specific DLQI questionnaire, hair disease-specific Scalpdex and the alopecia areata-specific instruments the Alopecia Areata Symptom Impact Scale or Alopecia Areata Quality of Life Index, despite the limited experience of their use. We hope that new treatment methods will be able to improve both clinical signs and health-related quality of life in patients with AA. In order to assess the outcomes of trials on these new treatment methods, it would be helpful when further development and validation of AA-specific instruments is being encouraged and also conducted

    Reduced invariants from cuspidal maps

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    We consider genus 1 enumerative invariants arising from the Smyth-Viscardi moduli space of stable maps from curves with nodes and cusps. We prove that these invariants are equal to the Vakil-Zinger reduced invariants for the quintic threefold, providing a modular interpretation of the latter
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