Reduced susceptibility to ischaemic brain damage following photochemical stroke in transgenic mice overexpressing the amyloid precursor protein

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Ambient halocarbon mixing ratios in 45 Chinese cities

During this study 158 whole air samples were collected in 45 Chinese cities in January and February 2001. The spatial distribution of different classes of halocarbons in the Chinese urban atmosphere, including chlorofluorocarbons (CFCs), hydrochlorofluorocarbons (HCFCs), hydrofluorocarbons (HFCs), Halon-1211, and other chlorinated compounds is presented and discussed. Most of these compounds were enhanced compared to background levels. However, the mean enhancement of CFCs was relatively small, with CFC-12 and CFC-11 increases of 6% (range 1-31%) and 10% (range 2-89%), respectively, with respect to the global background. On the contrary, strongly enhanced levels of CFC replacement compounds and halogenated compounds used as solvents were measured. The average Halon-1211 concentration exceeded the background of 4.3 pptv by 75% and was higher than 10 pptv in several cities. Methyl chloride mixing ratios were also strongly elevated (78% higher than background levels), which is likely related to the widespread use of coal and biofuel in China. © 2006 Elsevier Ltd. All rights reserved

The tip of the VgrG spike is essential to functional type VI secretion system assembly in Acinetobacter baumannii

The type VI secretion system (T6SS) is a critical weapon in bacterial warfare between Gram-negative bacteria. Although invaluable for niche establishment, this machine represents an energetic burden to its host bacterium

Lifelogging As An Extreme Form of Personal Information Management -- What Lessons To Learn

Personal data includes the digital footprints that we leave behind as part of our everyday activities, both online and offline in the real world. It includes data we collect ourselves, such as from wearables, as well as the data collected by others about our online behaviour and activities. Sometimes we are able to use the personal data we ourselves collect, in order to examine some parts of our lives but for the most part, our personal data is leveraged by third parties including internet companies, for services like targeted advertising and recommendations. Lifelogging is a form of extreme personal data gathering and in this article we present an overview of the tools used to manage access to lifelogs as demonstrated at the most recent of the annual Lifelog Search Challenge benchmarking workshops. Here, experimental systems are showcased in live, real time information seeking tasks by real users. This overview of these systems' capabilities show the range of possibilities for accessing our own personal data which may, in time, become more easily available as consumer-level services

Determinants of physicians’ intention to collect data exhaustively in registries: an exploratory study in Bamako’s community health centres

Background: The incomplete collection of health datais a prevalent problem in healthcare systems around theworld, especially in developing countries. Missing datahinders progress in population health and perpetuatesinefficiencies in healthcare systems.Objective: This study aims to identify the factors that predict the intention of physicians practicing in community health centres of Bamako, Mali, to collect data exhaustively in medical registries.Design: A cross sectional studyMethod: In January and February 2011, we conducted a study with a random sample of thirty two physicians practicing in community health centres of Bamako, using a questionnaire. Data was analyzed by using descriptive statistics, correlations and linear regression.Main outcomes measures: Trained investigators administered a questionnaire measuring physicians’ sociodemographic and professional characteristics as well as constructs from the Theory of Planned Behaviour.Results: Our results showed that physicians’ intention to collect data exhaustively is influenced by subjective norms and by the physician’s number of years in practice.Conclusions: the results of this study could be used as a guide for health workers and decision makers to improve the quality of health information collected in community health centers.Keywords: Physicians’ intention, exhaustive data collection, Bamako, Community Health Centre, Missing dat