613 research outputs found
Formation of phase lags at the cyclotron energies in the pulse profiles of magnetized, accreting neutron stars
Context: Accretion-powered X-ray pulsars show highly energy-dependent and
complex pulse-profile morphologies. Significant deviations from the average
pulse profile can appear, in particular close to the cyclotron line energies.
These deviations can be described as energy-dependent phase lags, that is, as
energy-dependent shifts of main features in the pulse profile. Aims: Using a
numerical study we explore the effect of cyclotron resonant scattering on
observable, energy-resolved pulse profiles. Methods: We generated the
observable emission as a function of spin phase, using Monte Carlo simulations
for cyclotron resonant scattering and a numerical ray-tracing routine
accounting for general relativistic light-bending effects on the intrinsic
emission from the accretion columns. Results: We find strong changes in the
pulse profile coincident with the cyclotron line energies. Features in the
pulse profile vary strongly with respect to the average pulse profile with the
observing geometry and shift and smear out in energy additionally when assuming
a non-static plasma. Conclusions: We demonstrate how phase lags at the
cyclotron energies arise as a consequence of the effects of angular
redistribution of X-rays by cyclotron resonance scattering in a strong magnetic
field combined with relativistic effects. We also show that phase lags are
strongly dependent on the accretion geometry. These intrinsic effects will in
principle allow us to constrain a system's accretion geometry.Comment: 4 pages, 4 figures; updated reference lis
Cyclotron resonant scattering feature simulations. I. Thermally averaged cyclotron scattering cross sections, mean free photon-path tables, and electron momentum sampling
Electron cyclotron resonant scattering features (CRSFs) are observed as
absorption-like lines in the spectra of X-ray pulsars. A significant fraction
of the computing time for Monte Carlo simulations of these quantum mechanical
features is spent on the calculation of the mean free path for each individual
photon before scattering, since it involves a complex numerical integration
over the scattering cross section and the (thermal) velocity distribution of
the scattering electrons.
We aim to numerically calculate interpolation tables which can be used in
CRSF simulations to sample the mean free path of the scattering photon and the
momentum of the scattering electron. The tables also contain all the
information required for sampling the scattering electron's final spin.
The tables were calculated using an adaptive Simpson integration scheme. The
energy and angle grids were refined until a prescribed accuracy is reached. The
tables are used by our simulation code to produce artificial CRSF spectra. The
electron momenta sampled during these simulations were analyzed and justified
using theoretically determined boundaries.
We present a complete set of tables suited for mean free path calculations of
Monte Carlo simulations of the cyclotron scattering process for conditions
expected in typical X-ray pulsar accretion columns (0.01<B/B_{crit}<=0.12,
where B_{crit}=4.413x10^{13} G and 3keV<=kT<15keV). The sampling of the tables
is chosen such that the results have an estimated relative error of at most
1/15 for all points in the grid. The tables are available online at
http://www.sternwarte.uni-erlangen.de/research/cyclo.Comment: A&A, in pres
Evaluation of antigens for the serodiagnosis of kala-azar and oriental sores by means of the indirect immunofluorescence antibody test (IFAT)
Antigens and corresponding sera were collected from travellers with leishmaniasis returning to Germany from different endemic areas of the old world. The antigenicity of these Leishmania strains, which were maintained in Syrian hamsters, was compared by indirect immunofluorescence (IFAT). Antigenicity was demonstrated by antibody titres in 18 sera from 11 patients. The amastigotic stages of nine strains of Leishmania donovani and four strains of Leishmania tropica were compared with each other and with the culture forms of insect flagellates (Strigomonas oncopelti and Leptomonas ctenocephali). Eighteen sera from 11 patients were available for antibody determination with these antigens. The maximal antibody titres in a single serum varied considerably depending on which antigen was used for the test. High antibody levels could only be maintained when Leishmania donovani was employed as the antigen, but considerable differences also occurred between the different strains of this species. The other antigens were weaker. No differences in antigenicity between amastigotes and promastigotes of the same strain were observed. It is important to select suitable antigens. Low titres may be of doubtful specificity and are a poor baseline for the fall in titre which is an essential index of effective treatment.Wir sammelten Parasiten und Seren von Reisenden, die aus verschiedenen endemischen Gebieten der Alten Welt mit einer Leishmaniasis nach Deutschland zurĂŒckkehrten. Die AntigenaktivitĂ€ten der isolierten und fortlaufend in Goldhamstern gehaltenenLeishmania-StĂ€mme wurden im indirekten Immunofluoreszenztest (IFAT) verglichen. Die AntigenitĂ€t wurde an Hand von Antikörpertitern in 18 Serumproben von 11 Patienten bewiesen. Neun StĂ€mme desLeishmania donovani-Komplexes und vierLeishmania tropica-Isolate wurden in ihrem amastigoten Stadium miteinander verglichen. Hinzu kamen zwei Insekten-Flagellaten als Kulturformen:Strigomonas oncopelti undLeptomonas ctenocephali. 18 Serumproben von 11 Patienten standen fĂŒr die Antikörperbestimmung mit diesen Antigenen zur VerfĂŒgung. Die maximalen Titerhöhen variierten in ein- und derselben antiserumprobe zum Teil erheblich, je nachdem, welches Antigen fĂŒr den Test benutzt wurde. Hohe Antikörpertiter konnten nur erhalten werden, wennLeishmania donovani als Antigen vorlag, es ergaben sich aber auch zwischen den einzelnen StĂ€mmen dieser Leishmaniaart erhebliche Unterschiede in der AntigenaktivitĂ€t. Antigene anderer Art erwiesen sich als wenig wirksam. Zwischen amastigoten und promastigoten Entwicklungsformen einesLeishmania donovani-Stammes konnten keine Unterschiede in der AntigenaktivitĂ€t erkannt werden. FĂŒr den Nachweis möglichst hoher Antikörpertiter im IFAT ist die Auswahl geeigneter Antigene von ausschlaggebender Bedeutung. Niedrige Titer erschweren deren Beurteilung als spezifisch und sind eine schlechte Ausgangsposition fĂŒr die Beobachtung des obligatorischen Titerabfalles nach erfolgreicher Therapie
Performance evaluation of flexible manufacturing systems under uncertain and dynamic situations
The present era demands the efficient modelling of any manufacturing system to enable it to cope with unforeseen situations on the shop floor. One of the complex issues affecting the performance of manufacturing systems is the scheduling of part types. In this paper, the authors have attempted to overcome the impact of uncertainties such as machine breakdowns, deadlocks, etc., by inserting slack that can absorb these disruptions without affecting the other scheduled activities. The impact of the flexibilities in this scenario is also investigated. The objective functions have been formulated in such a manner that a better trade-off between the uncertainties and flexibilities can be established. Consideration of automated guided vehicles (AGVs) in this scenario helps in the loading or unloading of part types in a better manner. In the recent past, a comprehensive literature survey revealed the supremacy of random search algorithms in evaluating the performance of these types of dynamic manufacturing system. The authors have used a metaheuristic known as the quick convergence simulated annealing (QCSA) algorithm, and employed it to resolve the dynamic manufacturing scenario. The metaheuristic encompasses a Cauchy distribution function as a probability function that helps in escaping the local minima in a better manner. Various machine breakdown scenarios are generated. A âheuristic gapâ is measured, and it indicates the effectiveness of the performance of the proposed methodology with the varying problem complexities. Statistical validation is also carried out, which helps in authenticating the effectiveness of the proposed approach. The efficacy of the proposed approach is also compared with deterministic priority rules
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Connections among ice, runoff and atmospheric forcing in the Beaufort Gyre
During SHEBA, thin ice and freshening of the Arctic Ocean surface in the Beafort Sea led to speculation that perennial sea ice was disappearing [McPhee et al., 1998]. Since 1987, we have collected salinity, ÎŽÂčâžO and Ba profiles near the initial SHEBA site and, in 1997, we ran a section out to SHEBA. Resolving fresh water into runoff and ice melt, we found a large background of Mackenzie River water with exceptional amounts in 1997 explaining much of the freshening at SHEBA. Ice melt went through a dramatic 4-6 m jump in the early 1990s coinciding with the atmospheric pressure field and sea-ice circulation becoming more cyclonic. The increase in sea-ice melt appears to be a thermal and mechanical response to a circulation regime shift. Should atmospheric circulation revert to the more anticyclonic mode, ice conditions can also be expected to revert although not necessarily to previous conditions.Copyrighted by the American Geophysical Union
Falkner-Skan Flow Over a Wedge with Slip Boundary Conditions
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76718/1/AIAA-2009-476-210.pd
X-ray emission from magnetized neutron star atmospheres at low mass accretion rates. I. Phase-averaged spectrum
Recent observations of X-ray pulsars at low luminosities allow, for the first
time, to compare theoretical models for the emission from highly magnetized
neutron star atmospheres at low mass accretion rates ( g s) with the broadband X-ray data. The purpose of this paper
is to investigate the spectral formation in the neutron star atmosphere at low
and to conduct a parameter study of physical properties of the
emitting region. We obtain the structure of the static atmosphere, assuming
that Coulomb collisions are the dominant deceleration process. The upper part
of the atmosphere is strongly heated by the braking plasma, reaching
temperatures of 30-40 keV, while its denser isothermal interior is much cooler
(~2 keV). We numerically solve the polarized radiative transfer in the
atmosphere with magnetic Compton scattering, free-free processes, and
non-thermal cyclotron emission due to possible collisional excitations of
electrons. The strongly polarized emitted spectrum has a double-hump shape that
is observed in low-luminosity X-ray pulsars. A low-energy "thermal" component
is dominated by extraordinary photons that can leave the atmosphere from deeper
layers due to their long mean free path at soft energies. We find that a
high-energy component is formed due to resonant Comptonization in the heated
non-isothermal part of the atmosphere even in the absence of collisional
excitations. The latter, however, affect the ratio of the two components. A
strong cyclotron line originates from the optically thin, uppermost zone. A fit
of the model to NuSTAR and Swift/XRT observations of GX 304-1 provides an
accurate description of the data with reasonable parameters. The model can thus
reproduce the characteristic double-hump spectrum observed in low-luminosity
X-ray pulsars and provides insights into spectral formation.Comment: 18 pages, 10 figures, A&A accepte
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A multi-model approach to X-ray pulsars: Connecting spectral and timing models to pin down the intrinsic emission characteristics of magnetized, accreting neutron stars
The emission characteristics of X-ray pulsars are governed by magnetospheric accretion within the Alfvén radius, leading to a direct coupling of accretion column properties and interactions at the magnetosphere. The complexity of the physical processes governing the formation of radiation within the accreted, strongly magnetized plasma has led to several sophisticated theoretical modelling efforts over the last decade, dedicated to either the formation of the broad band continuum, the formation of cyclotron resonance scattering features (CRSFs) or the formation of pulse profiles. While these individual approaches are powerful in themselves, they quickly reach their limits when aiming at a quantitative comparison to observational data. Too many fundamental parameters, describing the formation of the accretion columns and the systems' overall geometry are unconstrained and different models are often based on different fundamental assumptions, while everything is intertwined in the observed, highly phase-dependent spectra and energy-dependent pulse profiles. To name just one example: the (phase variable) line width of the CRSFs is highly dependent on the plasma temperature, the existence of B-field gradients (geometry) and observation angle, parameters which, in turn, drive the continuum radiation and are driven by the overall two-pole geometry for the light bending model respectively. This renders a parallel assessment of all available spectral and timing information by a compatible across-models-approach indispensable. In a collaboration of theoreticians and observers, we have been working on a model unification project over the last years, bringing together theoretical calculations of the Comptonized continuum, Monte Carlo simulations and Radiation Transfer calculations of CRSFs as well as a General Relativity (GR) light bending model for ray tracing of the incident emission pattern from both magnetic poles. The ultimate goal is to implement a unified fitting model for phase-resolved spectral and timing data analysis. We present the current status of this project
The HLA class II allele DRB1*1501 is over-represented in patients with idiopathic pulmonary fibrosis
Background: Idiopathic pulmonary fibrosis (IPF) is a progressive and medically refractory lung disease with a grim prognosis. Although the etiology of IPF remains perplexing, abnormal adaptive immune responses are evident in many afflicted patients. We hypothesized that perturbations of human leukocyte antigen (HLA) allele frequencies, which are often seen among patients with immunologic diseases, may also be present in IPF patients. Methods/Principal Findings: HLA alleles were determined in subpopulations of IPF and normal subjects using molecular typing methods. HLA-DRB1*15 was over-represented in a discovery cohort of 79 Caucasian IPF subjects who had lung transplantations at the University of Pittsburgh (36.7%) compared to normal reference populations. These findings were prospectively replicated in a validation cohort of 196 additional IPF subjects from four other U.S. medical centers that included both ambulatory patients and lung transplantation recipients. High-resolution typing was used to further define specific HLA-DRB1*15 alleles. DRB1*1501 prevalence in IPF subjects was similar among the 143 ambulatory patients and 132 transplant recipients (31.5% and 34.8%, respectively, p = 0.55). The aggregate prevalence of DRB1*1501 in IPF patients was significantly greater than among 285 healthy controls (33.1% vs. 20.0%, respectively, OR 2.0; 95%CI 1.3-2.9, p = 0.0004). IPF patients with DRB1*1501 (n = 91) tended to have decreased diffusing capacities for carbon monoxide (DLCO) compared to the 184 disease subjects who lacked this allele (37.8±1.7% vs. 42.8±1.4%, p = 0.036). Conclusions/Significance: DRB1*1501 is more prevalent among IPF patients than normal subjects, and may be associated with greater impairment of gas exchange. These data are novel evidence that immunogenetic processes can play a role in the susceptibility to and/or manifestations of IPF. Findings here of a disease association at the HLA-DR locus have broad pathogenic implications, illustrate a specific chromosomal area for incremental, targeted genomic study, and may identify a distinct clinical phenotype among patients with this enigmatic, morbid lung disease
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