1,279 research outputs found

    Epidemiology of Coronary Artery Disease

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    Rayleigh and depinning instabilities of forced liquid ridges on heterogeneous substrates

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    Depinning of two-dimensional liquid ridges and three-dimensional drops on an inclined substrate is studied within the lubrication approximation. The structures are pinned to wetting heterogeneities arising from variations of the strength of the short-range polar contribution to the disjoining pressure. The case of a periodic array of hydrophobic stripes transverse to the slope is studied in detail using a combination of direct numerical simulation and branch-following techniques. Under appropriate conditions the ridges may either depin and slide downslope as the slope is increased, or first breakup into drops via a transverse instability, prior to depinning. The different transition scenarios are examined together with the stability properties of the different possible states of the system.Comment: Physics synopsis link: http://physics.aps.org/synopsis-for/10.1103/PhysRevE.83.01630

    EFLUENTES, RESÍDUOS SÓLIDOS E EDUCAÇÃO AMBIENTAL: UMA DISCUSSÃO SOBRE O TEMA

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    Neste trabalho realiza-se um estudo bibliográfico sobre a educação ambiental e busca-se verificar a contribuição da mesma em relação à temática de resíduos sólidos e efluentes. Focou-se na bibliografia dos mais diversos autores para que fosse possível realizar-se uma interação entre educação ambiental e conceitos que tangem o tratamento de efluentes e resíduos sólidos. Ao final das colocações foi possível perceber que a educação ambiental pode ser uma aliada de organizações e cidadãos no que diz respeito à preservação do meio ambiente

    Photometry of GSC 762-110, a new triple-mode radially pulsating star

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    Stars pulsating in three radial modes are very rare; only three examples are known in the Galaxy. These stars are very useful since their periods may be measured very precisely, and this will constrain the global stellar parameters and the models of the star's interior. The purpose of this paper is to present a new example of the class of triple-mode radial pulsators. A search for candidate multi-mode pulsators was carried out in public survey data. Time-series photometry of one of the candidates, GSC 762-110, was performed. GSC 762-110 was found to be a triple-mode radial pulsator, with a fundamental period of 0.1945d and period ratios of 0.7641 and 0.8012. In addition two non-radial modes were found, for which the amplitude has diminished considerably over the last few years.Comment: Accepted for publication in Astronomy & Astrophysic

    Detection of Listeria monocytogenes in foods with a textile organic electrochemical transistor biosensor

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    Abstract: Foods contaminated by pathogens are responsible for foodborne diseases which have socioeconomic impacts. Many approaches have been extensively investigated to obtain specific and sensitive methods to detect pathogens in food, but they are often not easy to perform and require trained personnel. This work aims to propose a textile organic electrochemical transistor-based (OECT) biosensor to detect L. monocytogenes in food samples. The analyses were performed with culture-based methods, Listeria Precis™ method, PCR, and our textile OECT biosensor which used poly(3,4-ethylenedioxythiophene) (PEDOT):polystyrene sulfonate (PSS) (PEDOT:PSS) for doping the organic channel. Atomic force microscopy (AFM) was used to obtain topographic maps of the gold gate. The electrochemical activity on gate electrodes was measured and related to the concentration of DNA extracted from samples and hybridized to the specific capture probe immobilized onto the gold surface of the gate. This assay reached a limit of detection of 1.05 ng/μL, corresponding to 0.56 pM of L. monocytogenes ATCC 7644, and allowed the specific and rapid detection of L. monocytogenes in the analyzed samples. Keypoints: • Textile organic electrochemical transistors functionalized with a specific DNA probe • AFM topographic and surface potential maps of a functionalized gold gate surface • Comparison between the Listeria monocytogenes Precis™ method and an OECT biosenso

    Histological analysis of ACL reconstruction failures due to synthetic-ACL (LARS) ruptures

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    INTRODUCTION: Anterior Cruciate Ligament (ACL) reconstruction is an established surgical procedure. Synthetic ligaments represent an option for ACL reconstruction. Their popularity declined for the raising concerns due to re-ruptures, knee synovitis and early arthritis related to I and II generation artificial ligaments. The introduction of a III generation synthetic ligament (Ligament Advanced Reinforcement System-LARS) permitted renewed interest in the adoption of this kind of graft. Main purpose of our study was to describe the histological findings on samples obtained from a consecutive series of ACL revision surgeries due to LARS ACL reconstruction failures. Secondary aim was to determine the reason for LARS rupture. METHODS: In a period between 2016 and 2018 eleven patients underwent ACL revision surgery due to LARS ACL reconstruction failure. At the time of the arthroscopic procedure, samples of synovial membrane and remnants of the torn LARS were sent to the Pathological-Anatomy Institute of our Hospital for a histological analysis. RESULTS: Histological analysis of the synovial tissues confirmed the arthroscopic evidence of synovitis mainly characterized by chronic inflammation with predominance of multinucleated giant cells. The adoption of polarized light microscopy revealed the presence of brightly bi-refractive material (LARS wear particles) in the synovial tissue; at higher magnification wear debris were detected inside the cytoplasma of multi nucleated cells. The histological analysis of the removed LARS revealed a surrounding typical foreign body reaction with poor signs of fibrovascular ingrowth of the synthetic ligament. CONCLUSIONS: Our findings could not clearly advocate a unique mechanism of LARS-ACL reconstruction failure: biologic issues (poor tissue ingrowth) and mechanical issues (fibers properties and tunnel position) probably concur in a multi factorial manner. ACL reconstruction using artificial ligaments can not be considered a simple surgery. Artificial augments require some expertise and could therefore achieve better results if used by skilled sport surgeons other than trainees or low volume surgeons. The Authors believe that ACL reconstruction with synthetic devices still have restricted indications for selected patients (e.g. elderly patients who require a fast recovery, professional athlete, autologous tendons not available and/or refusing donor tendons). Our study arises additional suspicion on the unresponsiveness of synthetic fibers and claim some concern in the implantation of synthetic devices

    Sanidade, transmissão via semente e patogenicidade de fungos em sementes de Cedrela fissilis procedentes da Região Sul do Brasil.

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    Pesquisas relacionadas à patologia de sementes de espécies florestais nativas, especialmente aquelas mais aprofundadas, são escassas. Assim, o objetivo deste estudo foi avaliar a sanidade das sementes de cedro através de dois métodos de detecção, avaliar a transmissão de fungos associados às sementes para as plântulas e avaliar a patogenicidade de fungos associados às sementes e transmitidos para as plântulas. Para tanto, sementes de seis procedências, dentre os estados do Rio Grande do Sul, Santa Catarina e Paraná, foram utilizadas. Estas foram submetidas a testes de sanidade, pelos métodos do papel-filtro e batata-dextroseágar (BDA), a teste de transmissão via sementes para as plântulas e a teste de patogenicidade de isolados de Rhizoctonia sp., patógeno escolhido por ser o mais frequente nos testes de sanidade e transmitido via semente. Os fungos encontrados em ambos os testes foram: Pestalotia sp., Rhizoctonia sp., Penicillium sp., Phomopsis sp., Rhizopus sp., Aspergillus sp. e Fusarium sp. Ambos os métodos podem ser utilizados para teste de sanidade em sementes de cedro. Os fungos transmitidos via semente para plântula foram Fusarium sp. e Rhizoctonia sp., sendo que, estes causaram danos nas raízes e posterior tombamento. Foi identificado um isolado de Rhizoctonia sp. patogênico para plântulas de cedro, causando os mesmos sintomas relatados no teste de transmissão

    Coronary Spasm: Ethnic and Sex Differences

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    Coronary spasm (CS), which may occur at the epicardial (focal or diffuse spasm) and/or microvascular (microvascular spasm) level, is a well-established cause of myocardial ischaemia, in particular in patients with anginal chest pain despite unobstructed coronary arteries. The diagnosis of CS can be confirmed during coronary angiography by an additional provocation test with vasoactive substances such as acetylcholine. Due to partially inconsistent data from large clinical studies, especially between Asian and white CS patients, ethnic differences concerning the prevalence and angiographic patterns of CS seem to exist. Furthermore, several studies in patients with coronary vasomotor disorders pointed towards differences among male and female CS patients. This article gives an overview of ethnic- and sex-related differences in patients with CS
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