Hubungan Persepsi Mutu Pelayanan dengan Tingkat Kepuasan Pasien Puskesmas Perumnas di Kota Kendari Tahun 2016

Berkembangnya jenis pelayanan kesehatan terutama di puskesmas membuat mutu pelayanan kesehatan di puskesmas mudah terabaikan.Penelitian ini bertujuan untuk melihat korelasiantara persepsi mutu pelayanan administrasi, dokter, perawat, obat dan kelengkapan sarana dengantingkat kepuasan pasien puskesmas Perumnas. Penelitian ini adalah penelitian observasional analitikdengan metode survey dan pendekatan crossectional. Penelitian dilaksanakan pada bulan maret2016 di puskesmas Perumnas. Populasi dalam penelitian ini adalah 14.553 orang dengan besarsampel 100 orang. Analisis data menggunakan dispersi data, uji korelasi spearman dan analisis faktordengan metode varimax. Hasil penelitian menunjukkan bahwa terdapat korelasi yang bermaknaantara persepsi mutu pelayanan administrasi, dokter, perawat, obat dan kelengkapan sarana dengantingkat kepuasan pasien (p0,9,transformation matrix 0,771> 0,5) dan faktor kedua yaitu persepsi mutu pelayanan obat dankelengkapan sarana (rotated component matriks> 0,8, transformation matrix 0,637> 0,5),dimanafaktor pertama dapat menjelaskan faktor sebesar 95%. Terdapat korelasi yang positif antara keduafaktor dengan kepuasan pasien dengan kekuatan korelasi yang kuat (>0,5), dimana faktor pertama(persepsi pelayanan dokter dan perawat) memiliki kekuatan korelasi yang paling besar (0,70).Disarankan terutama bagi puskesmas untuk membenahi pelayanan yang diberikan kepada pasienterutama pelayanan dokter dan perawat

A review of foodborne Toxoplasma gondii with a special focus on its prevalence in Pakistan from 2000 to 2022

Third-world countries have a higher prevalence of food-related disorders than developed nations. Millions of people in underdeveloped countries are seriously at risk from the potential water supply contamination with protozoan diseases. Toxoplasma gondii is one of the important protozoans causing diseases in livestock and humans. Despite the standard tests for diagnosing this parasite and different treatment methods, the spread of these parasites is uncontrollable and rising every year due to other management disorders. In this review, we summarize etiopathogenesis and prevalence in Pakistan. We looked for papers reporting the seroprevalence of T. gondii in people and animals between 2000 and 2022 in different databases: PubMed, Google Scholar, ScienceDirect, Scopus, and Web of Science. Data on the seroprevalence of T. gondii in Pakistan's domestic animals (sheep and goats, horses, donkeys, mules, cattle, and buffaloes), domestic pets (cats and dogs), poultry and rodents, and humans were gathered. According to the findings, sheep had an estimated pooled seroprevalence of T. gondii that varied from 11.20 to 26.50 %, and goats from 24.50 to 38.40%. Whereas in buffalo the opposite trend was followed, and the prevalence was observed is 0% in 2022, in horses, donkeys, and mules, only one study was reported according to which a high prevalence was observed in mules (28.60%) followed by donkeys (23.50%) and horses (23.50%), in cats 38.5% prevalence was observed in a recent study and in dogs 28.43% observed, and in humans from 22 to 60%. Human beings are found to be the most affected species showing high prevalence among all. According to our findings, animals and pets not only serve as a reservoir for the parasite but also serve as a direct route for human infection with T. gondii. The diagnostic techniques used in the observed studies were mostly serological testing whereas only a few studies have only been observed with molecular testing. To know the exact pattern of the disease for its control, the trend of molecular and advanced testing should be adopted as it is more reliable. Moreover, to decrease the transmission chances of T. gondii to humans, it is crucial to manage T. gondii infections in non-human species

Nuclear Symmetry Energy: constraints from Giant Quadrupole Resonances and Parity Violating Electron Scattering

Experimental and theoretical efforts are being devoted to the study of observables that can shed light on the properties of the nuclear symmetry energy. We present our new results on the excitation energy [X. Roca-Maza et al., Phys. Rev. C 87, 034301 (2013)] and polarizability of the Isovector Giant Quadrupole Resonance (IVGQR), which has been the object of new experimental investigation [S. S. Henshaw et al., Phys. Rev. Lett. 107, 222501 (2011)]. We also present our theoretical analysis on the parity violating asymmetry at the kinematics of the Lead Radius Experiment [S. Abrahamyan et al. (PREx Collaboration), Phys. Rev. Lett. 108, 112502 (2012)] and highlight its relation with the density dependence of the symmetry energy [X. Roca-Maza et al., Phys. Rev. Lett. 106, 252501 (2011)].Comment: Proceedings - International Nuclear Physics Conference (INPC), Firenze 2 - 7 June 201

Fission half-lives of super-heavy nuclei in a microscopic approach

A systematic study of 160 heavy and super-heavy nuclei is performed in the Hartree-Fock-Bogoliubov approach with the finite range and density dependent Gogny force with the D1S parameter set. We show calculations in several approximations: with axially symmetric and reflexion symmetric wave functions, with axially symmetric and non-reflexion symmetric wave functions and finally some representative examples with triaxial wave functions are also discussed. Relevant properties of the ground state and along the fission path are thoroughly analyzed. Fission barriers, Q$_\alpha$-factors and lifetimes with respect to fission and $\alpha$-decay as well as other observables are discussed. Larger configuration spaces and more general HFB wave functions as compared to previous studies provide a very good agreement with the experimental data.Comment: 26 pages, 15 figure

Effect of differences in proton and neutron density distributions on fission barriers

The neutron and proton density distributions obtained in constrained Hartree-Fock-Bogolyubov calculations with the Gogny force along the fission paths of 232Th, 236U, 238U and 240Pu are analyzed. Significant differences in the multipole deformations of neutron and proton densities are found. The effect on potential energy surfaces and on barrier heights of an additional constraint imposing similar spatial distributions to neutrons and protons, as assumed in macroscopic-microscopic models, is studied.Comment: 5 pages in Latex, 4 figures in ep

Antimicrobial effect of Chitosan and Nano-Chitosan against some Pathogens and Spoilage Microorganisms

An experiment was conducted to investigate the antimicrobial effect of chitosan and nano-chitosan. Two Gram-negative, three Gram-positive bacteria and three fungal strains were used as test microorganisms. The obtained results indicated that 88% of nano-chitosan particle size was in the range of 93.76nm and 12% in 405nm. Nano-chitosan showed maximum antibacterial activity against S. aureus and L. monocytogenes with inhibition zone of 30mm (23µg/ml concentration) and the lowest 23mm with E. coli at the same concentration. Other tested bacteria were affected in different degrees. The MIC and MLC ranged between 64 to 256 and 128 to 512µg/ml, respectively. The highest effect was against S. aureus at 23.04µg/ml. Chitosan solution was found to have less antifungal activity against C. albicans when compared to nano-chitosan. MIC and MLC for chitosan and nano-chitosan were recorded at 64 and 128µg/ml with chitosan and 23.04 and 46.08µg/ml with nano-chitosan. The highest nano-chitosan activity was recorded against S. cerevisiae, 7 and 16µg/ml for MIC and MLC, respectively. Nano-chitosan at concentrations 3.0 and 4.5µg/ml were the most effective to retard fungal activity

Hybrid kernelised expectation maximisation for Bremsstrahlung SPECT reconstruction in SIRT with 90Y micro-spheres

BACKGROUND: Selective internal radiation therapy with Yttrium-90 microspheres is an effective therapy for liver cancer and liver metastases. Yttrium-90 is mainly a high-energy beta particle emitter. These beta particles emit Bremsstrahlung radiation during their interaction with tissue making post-therapy imaging of the radioactivity distribution feasible. Nevertheless, image quality and quantification is difficult due to the continuous energy spectrum which makes resolution modelling, attenuation and scatter estimation challenging and therefore the dosimetry quantification is inaccurate. As a consequence a reconstruction algorithm able to improve resolution could be beneficial. METHODS: In this study, the hybrid kernelised expectation maximisation (HKEM) is used to improve resolution and contrast and reduce noise, in addition a modified HKEM called frozen HKEM (FHKEM) is investigated to further reduce noise. The iterative part of the FHKEM kernel was frozen at the 72nd sub-iteration. When using ordered subsets algorithms the data is divided in smaller subsets and the smallest algorithm iterative step is called sub-iteration. A NEMA phantom with spherical inserts was used for the optimisation and validation of the algorithm, and data from 5 patients treated with Selective internal radiation therapy were used as proof of clinical relevance of the method. RESULTS: The results suggest a maximum improvement of 56% for region of interest mean recovery coefficient at fixed coefficient of variation and better identification of the hot volumes in the NEMA phantom. Similar improvements were achieved with patient data, showing 47% mean value improvement over the gold standard used in hospitals. CONCLUSIONS: Such quantitative improvements could facilitate improved dosimetry calculations with SPECT when treating patients with Selective internal radiation therapy, as well as provide a more visible position of the cancerous lesions in the liver

Triple modality image reconstruction of PET data using SPECT, PET, CT information increases lesion uptake in images of patients treated with radioembolization with [Formula: see text] micro-spheres.

PURPOSE: Nuclear medicine imaging modalities like computed tomography (CT), single photon emission CT (SPECT) and positron emission tomography (PET) are employed in the field of theranostics to estimate and plan the dose delivered to tumors and the surrounding tissues and to monitor the effect of the therapy. However, therapeutic radionuclides often provide poor images, which translate to inaccurate treatment planning and inadequate monitoring images. Multimodality information can be exploited in the reconstruction to enhance image quality. Triple modality PET/SPECT/CT scanners are particularly useful in this context due to the easier registration process between images. In this study, we propose to include PET, SPECT and CT information in the reconstruction of PET data. The method is applied to Yttrium-90 ([Formula: see text]Y) data. METHODS: Data from a NEMA phantom filled with [Formula: see text]Y were used for validation. PET, SPECT and CT data from 10 patients treated with Selective Internal Radiation Therapy (SIRT) were used. Different combinations of prior images using the Hybrid kernelized expectation maximization were investigated in terms of VOI activity and noise suppression. RESULTS: Our results show that triple modality PET reconstruction provides significantly higher uptake when compared to the method used as standard in the hospital and OSEM. In particular, using CT-guided SPECT images, as guiding information in the PET reconstruction significantly increases uptake quantification on tumoral lesions. CONCLUSION: This work proposes the first triple modality reconstruction method and demonstrates up to 69% lesion uptake increase over standard methods with SIRT [Formula: see text]Y patient data. Promising results are expected for other radionuclide combination used in theranostic applications using PET and SPECT