70 research outputs found
Optoelectronic Reservoir Computing
Reservoir computing is a recently introduced, highly efficient bio-inspired
approach for processing time dependent data. The basic scheme of reservoir
computing consists of a non linear recurrent dynamical system coupled to a
single input layer and a single output layer. Within these constraints many
implementations are possible. Here we report an opto-electronic implementation
of reservoir computing based on a recently proposed architecture consisting of
a single non linear node and a delay line. Our implementation is sufficiently
fast for real time information processing. We illustrate its performance on
tasks of practical importance such as nonlinear channel equalization and speech
recognition, and obtain results comparable to state of the art digital
implementations.Comment: Contains main paper and two Supplementary Material
Online Training of an Opto-Electronic Reservoir Computer
Reservoir Computing is a bio-inspired computing paradigm for processing time dependent signals. Its analog implementations equal and sometimes outperform other digital algorithms on a series of benchmark tasks. Their performance can be increased by switching from offline to online training method. Here we present the first online trained opto-electronic reservoir computer. The system is tested on a channel equalisation task and the algorithm is executed by an FPGA chip. We report performances close to previous implementations and demonstrate the benefits of online training on a non-stationary task that could not be easily solved using offline methods.info:eu-repo/semantics/publishe
Brain energy rescue:an emerging therapeutic concept for neurodegenerative disorders of ageing
The brain requires a continuous supply of energy in the form of ATP, most of which is produced from glucose by oxidative phosphorylation in mitochondria, complemented by aerobic glycolysis in the cytoplasm. When glucose levels are limited, ketone bodies generated in the liver and lactate derived from exercising skeletal muscle can also become important energy substrates for the brain. In neurodegenerative disorders of ageing, brain glucose metabolism deteriorates in a progressive, region-specific and disease-specific manner — a problem that is best characterized in Alzheimer disease, where it begins presymptomatically. This Review discusses the status and prospects of therapeutic strategies for countering neurodegenerative disorders of ageing by improving, preserving or rescuing brain energetics. The approaches described include restoring oxidative phosphorylation and glycolysis, increasing insulin sensitivity, correcting mitochondrial dysfunction, ketone-based interventions, acting via hormones that modulate cerebral energetics, RNA therapeutics and complementary multimodal lifestyle changes
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