794 research outputs found
The role of Mie scattering in the seeding of matter-wave superradiance
Matter-wave superradiance is based on the interplay between ultracold atoms
coherently organized in momentum space and a backscattered wave. Here, we show
that this mechanism may be triggered by Mie scattering from the atomic cloud.
We show how the laser light populates the modes of the cloud, and thus imprints
a phase gradient on the excited atomic dipoles. The interference with the atoms
in the ground state results in a grating, that in turn generates coherent
emission, contributing to the backward light wave onset. The atomic recoil
'halos' created by the scattered light exhibit a strong anisotropy, in contrast
to single-atom scattering
Absorption from Finite-size Microperforated Panels at Arbitrary Incidence Angles
A rigid microperforated panel combined with a finite-depth air space can absorb sound effectively. Various studies of these systems have been performed and it has been found that hole configuration and backing depth are the primary factors that determine their absorption. However, the effects of panel flexibility and the finite size of the supported membrane segments have not been considered as extensively. In this present work, a two-dimensional model for arbitrary incidence angles was used to predict the sound absorption of an infinite array of finite-size, flexible microperforated panels. The absorption of various microperforated panels was measured in standing wave tubes and compared to predictions to verify the model at normal incidence. The effects of two different types of backing spaces, i.e., segmented and unsegmented, were compared. It was found that the segmented backing space is approximately locally reacting: as a result, the absorption at low frequencies is larger than that for the unsegmented backing space case. It was also found that the absorption from an array of finite-size microperforated panels can be successfully predicted with a knowledge of the panel’s physical material properties (e.g., flexural stiffness, loss factor, and mass per unit area) and hole configuration (e.g., hole size, film thickness, and number of holes per unit area)
Experimental perspectives for systems based on long-range interactions
The possibility of observing phenomena peculiar to long-range interactions,
and more specifically in the so-called Quasi-Stationary State (QSS) regime is
investigated within the framework of two devices, namely the Free-Electron
Laser (FEL) and the Collective Atomic Recoil Laser (CARL). The QSS dynamics has
been mostly studied using the Hamiltonian Mean-Field (HMF) toy model,
demonstrating in particular the presence of first versus second order phase
transitions from magnetized to unmagnetized regimes in the case of HMF. Here,
we give evidence of the strong connections between the HMF model and the
dynamics of the two mentioned devices, and we discuss the perspectives to
observe some specific QSS features experimentally. In particular, a dynamical
analog of the phase transition is present in the FEL and in the CARL in its
conservative regime. Regarding the dissipative CARL, a formal link is
established with the HMF model. For both FEL and CARL, calculations are
performed with reference to existing experimental devices, namely the
FERMI@Elettra FEL under construction at Sincrotrone Trieste (Italy) and the
CARL system at LENS in Florence (Italy)
Molecular Characterization of Glycopeptide-Resistant Enterococci from Hospitals of the Picardy Region (France)
We studied 138 glycopeptide-resistant enterococci (GRE) strains, consisting of 131 glycopeptide-resistant Enterococcus faecium (GREfm) and 7 glycopeptide-resistant Enterococcus faecalis (GREfs). The GREfm strains were resistant to penicillin, ampicillin, vancomycin, and teicoplanin, while the GREfs strains were only resistant to vancomycin and teicoplanin. The van A gene was the only glycopeptide determinant present in all GRE isolates investigated. Genes coding for Hyl and Hyl+ Esp were detected in 39 (29.8%) and 92 (70.2%) of the 131 GREfm isolates, respectively. Three of the 7 GREfs were positive for gelE+asa 1 genes, 3 for gel E gene, and 1 for asa 1 gene. The genetic relationship between the 138 GRE was analyzed by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST). GREfm isolates were clustered in a single genogroup (pulsotype A), and GREfs were clustered in six genogroups (pulsotypes B-G). Among the isolates investigated by MLST, only 18 PCR products were sequenced (12 E. faecium and 6 E. faecalis), and 9 sequence types (STs) were identified
Experiences that \u201creach the heart\u201d. Taking part in a whole body dissection course at the University of Malta
This article summarizes the activities of the four-week whole body dissection course the main authors participated in in August 2016 at the dissection hall of the University of Malta (UoM). Our team comprised 10 second-year medicine students from University of Palermo chosen among who had passed the Human Anatomy exam brilliantly. The need to move to the UoM to take part in such activity derives from the lack of practice approach in Italian schools of medicine, focused mostly on the theoretical studies, neglecting practical experience. The heart dissection reveal itself as a huge opportunity to finally apply our anatomical knowledge, improving it and enabling us to compare images took from books to the actual organ. We had the chance to handle a real heart, to appreciate its weight and consistence. We took part in coronary artery courses focusing on their functions within the heart machinery.This article summarizes the activities of the four-week whole body dissection course the main authors partecipated in August 2016 at the dissection hall of the University of Malta (UoM). Our team comprised 10 second-year medicine students from University of Palermo chosen among who had passed the Human Anatomy exam brilliantly. The need to molve to the UoM to take part in such activity derives from the lack of practice approach in Italian schools of medicine, focused mostly on the theoretical studies, neglecting practical experience. The heart dissection reveal itself as a huge opportunity to finally apply our anatomical knowledge, improving it and enabling us to compare image took from books to the actual organ. We had the chance to handle a real heart, to appreciate its weight and consistence. We took part in coronary artery courses focusing on their functions within the heart machinery
Progesterone receptor membrane component 1 facilitates Ca²⁺ signal amplification between endosomes and the endoplasmic reticulum
Membrane contact sites (MCSs) between endosomes and the endoplasmic reticulum (ER) are thought to act as specialized trigger zones for Ca2+ signaling, where local Ca2+ released via endolysosomal ion channels is amplified by ER Ca2+-sensitive Ca2+ channels into global Ca2+ signals. Such amplification is integral to the action of the second messenger, nicotinic acid adenine dinucleotide phosphate (NAADP). However, functional regulators of inter-organellar Ca2+ crosstalk between endosomes and the ER remain poorly defined. Here, we identify progesterone receptor membrane component 1 (PGRMC1), an ER transmembrane protein that undergoes a unique heme-dependent dimerization, as an interactor of the endosomal two pore channel, TPC1. NAADP-dependent Ca2+ signals were potentiated by PGRMC1 overexpression through enhanced functional coupling between endosomal and ER Ca2+ stores and inhibited upon PGRMC1 knockdown. Point mutants in PGMRC1 or pharmacological manipulations that reduced its interaction with TPC1 were without effect. PGRMC1 therefore serves as a TPC1 interactor that regulates ER-endosomal coupling with functional implications for cellular Ca2+ dynamics and potentially the distribution of heme
Appendagite épiploïque primitive: à propos de cinq cas
La torsion de frange épiploïque (ou appendagite) est une pathologie rare qui survient principalement chez les adultes entre 20 et 50 ans.L'incidence de cette pathologie n'est pas réellement connue et elle varie de 2 à 7% chez les patients hospitalisés pour suspicion d'appendicite oude sigmoïdite. Nous rapportons cinq cas d'appendagites dont nous précisons les particularités cliniques, radiologiques et thérapeutiques. Il s'agit de 5 patients dont l'âge moyen est de 34.6 ans (24-55). Le sexe ratio est de 1.5. Le principal motif de consultation était un syndrome douloureux de l'abdomen principalement au niveau de la fosse iliaque droite. L'examen abdominal montrait toujours une sensibilité localisée. La fièvre était présente chez 3 patients. Le bilan biologique révèle un syndrome inflammatoire biologique chez trois patients. Les examens complémentaires radiologiques en particulier échographie abdominale et TDM abdominale ont éliminé formellement une urgence chirurgicale et ont évoqué le diagnostic d'appendagite dans trois cas. Trois patients ont bénéficié d'une coelioscopie diagnostique confirmant le diagnostic d'appendagite. L'évolution était favorable chez tous les patients. Les appendagites épiploïques primitives sont des étiologies rares et sous-estimées de syndrome abdominal aigu. Le diagnostic peut être affirmé par imagerie notamment avec le scanner hélicoïdal injecté, permettant d'instaurer ainsi un traitement médical premier et d'éviter un traitement chirurgical et des hospitalisations excessives
Recommendations for core critical care ultrasound competencies as a part of specialist training in multidisciplinary intensive care: a framework proposed by the European Society of Intensive Care Medicine (ESICM)
© 2020 The Author(s). Critical care ultrasound (CCUS) is an essential component of intensive care practice. Although existing international guidelines have focused on training principles and determining competency in CCUS, few countries have managed to operationalize this guidance into an accessible, well-structured programme for clinicians training in multidisciplinary intensive care. We seek to update and reaffirm appropriate CCUS scope so that it may be integrated into the international Competency-based Training in Intensive Care Medicine. The resulting recommendations offer the most contemporary and evolved set of core CCUS competencies for an intensive care clinician yet described. Importantly, we discuss the rationale for inclusion but also exclusion of competencies listed. Background/aim: Critical care ultrasound (CCUS) is an essential component of intensive care practice. The purpose of this consensus document is to determine those CCUS competencies that should be a mandatory part of training in multidisciplinary intensive care. Methods: A three-round Delphi method followed by face-to-face meeting among 32 CCUS experts nominated by the European Society of Intensive Care Medicine. Agreement of at least 90% of experts was needed in order to enlist a competency as mandatory. Results: The final list of competencies includes 15 echocardiographic, 5 thoracic, 4 abdominal, deep vein thrombosis diagnosis and central venous access aid. Conclusion: The resulting recommendations offer the most contemporary and evolved set of core CCUS competencies for an intensive care clinician yet described
Анализ механических состояний силовых систем. Сообщение 1. Предельное состояние
Изложены основы теории предельных состояний силовых систем, которые работают в
условиях сложного нагружения (механическая усталость, трение и изнашивание, температура,
электрохимическая коррозия). Получен энергетический критерий предельного состояния
и описаны методы определения его параметров. Записаны условия прочности с учетом
как циклической, так и контактной нагрузок.Викладено основи теорії граничних станів силових систем, що працюють в
умовах складного навантаження (механічна утома, тертя та спрацьовування,
температура, електрохімічна корозія). Отримано енергетичний критерій граничного
стану та описано методи визначення його параметрів. Записано
рівняння міцності з урахуванням як циклічного, так і контактного навантажень.Fundamentals of the theory of ultimate states in
force systems operating under complex loading
(mechanical fatigue, friction and wear, temperature,
and electrochemical corrosion) have been
described. Energy criterion of an ultimate state
has been obtained and methods for calculating
its parameters are given. Strength conditions
taking into account both cyclic and contact
loads are described
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