599 research outputs found

    Energy-efficiency evaluation of Intel KNL for HPC workloads

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    Energy consumption is increasingly becoming a limiting factor to the design of faster large-scale parallel systems, and development of energy-efficient and energy-aware applications is today a relevant issue for HPC code-developer communities. In this work we focus on energy performance of the Knights Landing (KNL) Xeon Phi, the latest many-core architecture processor introduced by Intel into the HPC market. We take into account the 64-core Xeon Phi 7230, and analyze its energy performance using both the on-chip MCDRAM and the regular DDR4 system memory as main storage for the application data-domain. As a benchmark application we use a Lattice Boltzmann code heavily optimized for this architecture and implemented using different memory data layouts to store its lattice. We assessthen the energy consumption using different memory data-layouts, kind of memory (DDR4 or MCDRAM) and number of threads per core

    Evolution of a double-front Rayleigh-Taylor system using a GPU-based high resolution thermal Lattice-Boltzmann model

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    We study the turbulent evolution originated from a system subjected to a Rayleigh-Taylor instability with a double density at high resolution in a 2 dimensional geometry using a highly optimized thermal Lattice Boltzmann code for GPUs. The novelty of our investigation stems from the initial condition, given by the superposition of three layers with three different densities, leading to the development of two Rayleigh-Taylor fronts that expand upward and downward and collide in the middle of the cell. By using high resolution numerical data we highlight the effects induced by the collision of the two turbulent fronts in the long time asymptotic regime. We also provide details on the optimized Lattice-Boltzmann code that we have run on a cluster of GPU

    FER: A Benchmark for the Roofline Analysis of FPGA Based HPC Accelerators

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    Nowadays, the use of hardware accelerators to boost the performance of HPC applications is a consolidated practice, and among others, GPUs are by far the most widespread. More recently, some data centers have successfully deployed also FPGA accelerated systems, especially to boost machine learning inference algorithms. Given the growing use of machine learning methods in various computational fields, and the increasing interest towards reconfigurable architectures, we may expect that in the near future FPGA based accelerators will be more common in HPC systems, and that they could be exploited also to accelerate general purpose HPC workloads. In view of this, tools able to benchmark FPGAs in the context of HPC are necessary for code developers to estimate the performance of applications, as well as for computer architects to model that of systems at scale. To fulfill these needs, we have developed FER (FPGA Empirical Roofline), a benchmarking tool able to empirically measure the computing performance of FPGA based accelerators, as well as the bandwidth of their on-chip and off-chip memories. FER measurements enable to draw Roofline plots for FPGAs, allowing for performance comparisons with other processors, such as CPUs and GPUs, and to estimate at the same time the performance upper-bounds that applications could achieve on a target device. In this paper we describe the theoretical model on which FER relies, its implementation details, and the results measured on Xilinx Alveo accelerator cards

    Herbal highs: review on psychoactive effects and neuropharmacology

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    Background: A new trend among users of new psychoactive substances’ the consumption of “herbal highs”: plant parts containing psychoactive substances. Most of the substances extracted from herbs, in old centuries were at the centre of religious ceremonies of ancient civilizations. Currently, these herbal products are mainly sold by internet web sites and easily obtained since some of them have no legal restriction. Objective: We reviewed psychoactive effects and neuropharmacology of the most used “herbal highs” with characterized active principles, with studies reporting mechanisms of action, pharmacological and subjective effects, eventual secondary effects including intoxications and/or fatalities Method: The PubMed database was searched using the following key.words: herbal highs, Argyreia nervosa, Ipomoea violacea and Rivea corymbosa; Catha edulis; Datura stramonium; Piper methysticum; Mitragyna speciosa. Results: Psychoactive plants here reviewed have been known and used from ancient times, even if for some of them limited information still exist regarding subjective and neuropharmacological effects and consequent eventual toxicity when plants are used alone or in combination with “classical” drugs of abuse. Conclusion: Some “herbal highs” should be classified as harmful drugs since chronic administration has been linked with addiction and cognitive impairment; for some others taking into consideration only the recent trends of abuse, studies investigating these aspects are lacking

    Advanced Formation Fluid Evaluation While Drilling with a New Heavy Gas Detector

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    In this paper, a chromatograph which exploits the benefits of FID technology optimized for the high resolution detection of heavier hydrocarbon gas components is described. The components analyzed span from n-hexane to toluene. Flame Ionization Detector (FID) technology is not new to gas detection on the field, however it had never been applied to the detection of gases heavier than n-pentane. The instrumentation has been installed and run on a number of wells in different fields and countries, and it has operated as a complement of an advanced surface logging system for a period of two years. Unlike other technologies presently utilized for this scope, this system reduces dedicated equipment and personnel to a minimum. The results presented show the clear identification of formation fluid contacts with higher accuracy than standard light gas detectors, the recognition of contaminants within the drilling fluid, and the practicality of operating an advanced gas detection system with minimal operational and logistic footprint. Some of the indications obtained challenge common beliefs about gas detection: consistent extraction of heavy hydrocarbon gases from the drilling fluid is possible at relatively low temperatures, provided that the entire gas extraction system is rigorously controlled in terms of gas sample pressure, flow, and temperature. Furthermore, gas data analysis can yield indications on the fluid composition even when the gases analyzed are in extremely low quantity. The system utilizes known technologies, developed and optimized to obtain new results. The system supports formation evaluation when LWD or wireline can be inconclusive, in the presence of a low porosity pay or fresh water. It can also guide and optimize the MDT testing program. Furthermore, the system takes into account the constraints of drilling operations, and strikes a balance between data accuracy and practicality of the application

    Prevalence of somatisation as a determinant of burnout amongst staff working in drug and alcohol services

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    Purpose: This study explored the prevalence of somatisation as a determinant of burnout amongst drug and alcohol staff in the UK. Design/methodology/approach: The study employed a cross-sectional design utilising a self-completion online questionnaire. Data was collected from substance misuse workers across England and Wales. 165 responses were eligible for analysis, yielding a response rate of 5%. Burnout and somatization were measured with Maslach’s Burnout Inventory and the Physical Symptoms Inventory. Findings: The prevalence of somatic symptoms was relatively low in the sample studied. The reported levels of burnout were moderate. Personal accomplishment remained high in the sample. There was a strong association between burnout and incidence of stress related somatic symptoms, with higher levels of burnout correlating with multiple symptoms. Research limitations/implications: It was not possible to determine the extent of non-response bias, as at the time of the study there was no information available relating to the characteristics of drug and alcohol staff in the selected services. Therefore, as the response rate was very low (5%) it was recognised that non-response bias might have affected the findings, in such way that non-respondents may have differed in their experiences of work stress, satisfaction, burnout and health outcomes. Practical implications: Despite the limitations, the study provided practical information relating to burnout vulnerability and associated physical symptoms in this specific occupational group. These findings can support employers to address staff wellbeing with a view to prevent burnout and reduce existing levels of burnout and related somatic symptoms, and improve job performance, job satisfaction, and staff retention through making appropriate adjustments, such as developing staff-wellbeing programmes. These adjustments could potentially contribute to improvement in substance misuse practice, through maintenance of healthy and satisfied workforce. Social implications: Originality/value: There is very few studies looking at burnout in drug and alcohol staff. This study is also novel in a way that it reveals correlations between a variety of specific stress related physical symptoms and the three components of burnout

    Recreational Drug Misuse and Its Potential Contribution to Male Fertility Levels’ Decline: A Narrative Review

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    Recreational drug intake may be associated with a range of medical untoward consequences, including male infertility. However, as the related evidence is still limited, the main outcome of this review is to provide a better understanding of the existence of any association between recreational drug misuse and male fertility levels’ decline. Whilst searching the MEDLINE/PubMed, a comprehensive overview of the literature regarding male infertility and substances of abuse (e.g., phytocannabinoids, opiates/opioids, stimulants, ‘herbal highs’, psychedelics, and ‘novel psychoactive substances) was here undertaken. Due to the paucity of robust, high-quality, empirical, human studies, a narrative strategy was here preferred over a systematic approach. Relevant data are qualitatively analyzed and presented in a table. Although most available evidence is in support of a detrimental role of cannabis on human spermatogenesis, a few remaining studies failed to document any effect of this drug on seminal quality, and it is not clear to which extent this drug impacts fertility rates/time to pregnancy. The current understanding of the impact of opiate-, cocaine- and amphetamine/stimulant-misuse on human reproduction is widely unknown, and most studies dealing with this matter represent only an extrapolation of data derived from specific clinical circumstances. Although the message of ‘no smoking, no alcohol and no street drugs’ should always be offered as good health advice to all patients seeking medical help for fertility issues, robust scientific clinical evidence in support of a direct detrimental impact of recreational drugs on spermatogenesis is scant to date

    Matched filters for coalescing binaries detection on massively parallel computers

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    We discuss some computational problems associated to matched filtering of experimental signals from gravitational wave interferometric detectors in a parallel-processing environment. We then specialize our discussion to the use of the APEmille and apeNEXT processors for this task. Finally, we accurately estimate the performance of an APEmille system on a computational load appropriate for the LIGO and VIRGO experiments, and extrapolate our results to apeNEXT.Comment: 19 pages, 6 figure

    Build up of yield stress fluids via chaotic emulsification

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    Stabilised dense emulsions display a rich phenomenology connecting microstructure and rheology. In this work, we study how an emulsion with a finite yield stress can be built via large-scale stirring. By gradually increasing the volume fraction of the dispersed minority phase, under the constant action of a stirring force, we are able to achieve a volume fraction close to (Formula presented.). Despite the fact that our system is highly concentrated and not yet turbulent we observe a droplet size distribution consistent with the (Formula presented.) scaling, often associated with inertial range droplets breakup. We report that the polydispersity of droplet sizes correlates with the dynamics of the emulsion formation process. Additionally, we quantify the visco-elastic properties of the dense emulsion finally obtained and we demonstrate the presence of a finite yield stress. The approach reported can pave the way to a quantitative understanding of the complex interplay between the dynamics of mesoscale constituents and the large-scale flow properties of yield stress fluids
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