13 research outputs found
Exploring relationship between environmentalism and consumerism in a market economy society: a structured systematic literature review
Managing environmental sustainability has become a critical challenge and an essential agenda for academics and corporations alike. This study conducted evidence-based research to explore whether it is possible to maintain a balance between environmentalism and consumerism in a capitalist society. A triangulated approach is followed by combining systematic literature review (SLR) and text mining for cross-validation, thus, limiting subjective bias. The findings suggest that, although, it is possible to achieve a balance in the long run but this necessitate enormous amount of efforts and resources due to the complexity and paradoxical nature of environmentalism and consumerism coupled with the current way of capitalist societies’ life. Building on the findings and the Operations Management Input-Transformation-Output model, a research framework is proposed. The proposed framework suggests that to keep a balance between environmentalism and consumerism in a capitalist society, a progressive and transformational change could be instrumental for a viable solution. Finally, building on current gaps in the research domain, six future research directions are proposed to carry forward the notion of environmentalism and consumerism in a capitalist society
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The gut microbiota: a major player in the toxicity of environmental pollutants?
Exposure to environmental chemicals has been linked to various health disorders, including obesity, type 2 diabetes, cancer and dysregulation of the immune and reproductive systems, whereas the gastrointestinal microbiota critically contributes to a variety of host metabolic and immune functions. We aimed to evaluate the bidirectional relationship between gut bacteria and environmental pollutants and to assess the toxicological relevance of the bacteria–xenobiotic interplay for the host. We examined studies using isolated bacteria, faecal or caecal suspensions—germ-free or antibiotic-treated animals—as well as animals reassociated with a microbiota exposed to environmental chemicals. The literature indicates that gut microbes have an extensive capacity to metabolise environmental chemicals that can be classified in five core enzymatic families (azoreductases, nitroreductases, β-glucuronidases, sulfatases and β-lyases) unequivocally involved in the metabolism of >30 environmental contaminants. There is clear evidence that bacteria-dependent metabolism of pollutants modulates the toxicity for the host. Conversely, environmental contaminants from various chemical families have been shown to alter the composition and/or the metabolic activity of the gastrointestinal bacteria, which may be an important factor contributing to shape an individual’s microbiotype. The physiological consequences of these alterations have not been studied in details but pollutant-induced alterations of the gut bacteria are likely to contribute to their toxicity. In conclusion, there is a body of evidence suggesting that gut microbiota are a major, yet underestimated element that must be considered to fully evaluate the toxicity of environmental contaminants
Effectiveness of various types and norms of fertilizers in increasing the productivity of cultivated crops and the fertility of gray forest soil in the Pre-Kama Area of Tatarstan
The article discusses the effectiveness of various types and norms of organic fertilizers in improving soil fertility, productivity and crop production quality, as well as crop rotation productivity in a comparative aspect with the estimated norms of mineral fertilizers for obtaining the planned yield. Various norms of thermally dried granulated chicken manure were studied, its suitability as an environmentally safe complex organic fertilizer and its effectiveness in increasing yields, produce quality, soil fertility and crop rotation productivity compared with traditional manure, buckwheat green manure crop, mineral fertilizers and natural nutritional background were established. The economic efficiency of the use of various types of fertilizers in crop rotation is determined and its increase to a profitability level of 74–222 % depending on the type and norms of fertilizers is established
Isoforms of Base Excision Repair Enzymes Produced by Alternative Splicing
Transcripts of many enzymes involved in base excision repair (BER) undergo extensive alternative splicing, but functions of the corresponding alternative splice variants remain largely unexplored. In this review, we cover the studies describing the common alternatively spliced isoforms and disease-associated variants of DNA glycosylases, AP-endonuclease 1, and DNA polymerase beta. We also discuss the roles of alternative splicing in the regulation of their expression, catalytic activities, and intracellular transport