Computational Modeling of Silicate Glasses: A Quantitative Structure-Property Relationship Perspective

This article reviews the present state of Quantitative Structure-Property Relationships (QSPR) in glass design and gives an outlook into future developments. First an overview is given of the statistical methodology, with particular emphasis to the integration of QSPR with molecular dynamics simulations to derive informative structural descriptors. Then, the potentiality of this approach as a tool for interpretative and predictive purposes is highlighted by a number of recent inspiring applications

in keeping with the spirit of the albertine statute constitutionalisation of the national unification

This chapter deals with the difficult process of constitutionalisation which characterised Italian Unification. Constitutionalisation is a long-term phenomenon which had the purpose of giving constitutional forms to the Nation. The promulgation of the Albertine Statute is more the start than the arrival of this phenomenon. The focus of this investigation is, therefore, to study the Constitution through its evolution paying particular attention to the process of legal integration within the structures of the Albertine Statute and to the amendment mechanisms of the constitutional text. The preamble of the Albertine Statute speaks of «perpetual and irrevocable fundamental law». The word «perpetual» meant the prohibition of revoking constitutional concession, while the word «irrevocable» was intended as a pact between the Sovereign and the Nation. Over the years, very few were the changes to the letter of the Albertine Statute. The interpretation and the practice represented the most important mechanisms of constitutional change (implicit constitutional changes). A primary role was acknowledged to non-written norms. In this perspective, it may well be said that the Italian Constitution consisted in something more than the written text and dwelt in the spirit and not in the letter of the Albertine Statute

Anti-refugee and Immigrant Representation in Three German Online Illustrations

Social criticism is often showed in various forms, one of it is through an illustration. Thus, many people ultimately poured their aspirations, criticism and even innuendo into a drawing. The easy access to the internet today also makes the illustrators take part in doing literary works that are published online. Through the semiotic theory of Ferdinand de Saussure, this paper analyses three online illustrations made by German cartoonists and illustrators; Schwarwel, Harm Bengen, and Freimut Woessner. These three corpuses are published online through their website. The result of this research indicates that the illustrations by Schwarwel, Harm Bengen, and Freimut Woessner represent a rejection of German refugees and immigrant in the political, educational and social sphere

L\u2019assistenza domiciliare al paziente tracheotomizzato: esperienza di valutazione del livello di soddisfazione nella citt\ue0 di Milano

Home care for tracheotomised patients appears to be a relevant problem in health care management. In order to allow patients to be cured at home high care standard have to be assured, and a multidisciplinary level of assistance implemented for preventing complications like respiratory infections. This study was conducted in order to assess patients and/or care givers level of satisfaction through a telephone survey. It was aimed at allowing those responsible for the given services to assess whether improvements can be achieved particularly in so far as the actual clinical and managerial pathway is concerned

Synthesis, Characterization and Stereoselective Catalytic Oxidations of Chelated Deuterohaemin-Glycyl-L-Histidine Complexes

The manuscript reports on the synthesis and characterization of a series of chelated deuterohaemin-glycyl-L-histidine Complexes. They are able to perform stereoselective catalytic oxidations of phenols in the presence of hydrogen peroxide.

Design, synthesis and SAR analysis of novel selective sigma1 ligands

Abstract: A new series of arylalkyl- and alkenylamines was designed, synthesized, and evaluated for binding to sigma1 and sigma2 receptors. Many compounds exhibited nanomolar affinity for sigma1 subtype receptor with good selectivity over sigma2. A molecular modeling study was conducted in order to rationalize the experimental data, and the structure-receptor affinities are discussed