293 research outputs found

    Automatic student attendance register using RFID

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    Published ArticleThe purpose of this project is to investigate the application of Radio Frequency Identification, RFID, to automatic student attendance register. The aim is that the students in any class can be recorded when they carry their student cards with them without having to individually swipe the card or allocate special interaction time. The successful implementation of this proposal will facilitate such record keeping in a non-intrusive and efficient manner and will provide the platform for further research on the correlation between attendance and performance of the students. The opportunity for related research is identified regarding the range of the parameters involved, ensuring that individual identifications do not clash and interfacing challenges with the central record keeping are overcome

    Infections, atherosclerosis, and coronary heart disease.

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    Atherosclerosis is a chronic inflammatory disease. Pathophysiological similarities between chronic infections and atherosclerosis triggered interest in a clinical association between these conditions. Various infectious microbes have been linked to atherosclerotic vascular disease in epidemiological studies. However, this association failed to satisfy the Koch's postulates of causation with multiple clinical trials demonstrating inefficacy of anti-infective therapies in mitigating atherosclerotic cardiovascular events. Identification of underlying pathophysiological mechanisms and experience with vaccination against various infectious agents has ushered a new avenue of efforts in the development of an anti-atherosclerotic vaccine. Studies in animal models have identified various innate and adaptive immune pathways in atherosclerosis. In this review, we discuss the patho-biological link between chronic infections and atherosclerosis, evaluate existing evidence of animal and human trials on the association between infections and cardiovascular disease and introduce the concept of an anti-atherosclerotic vaccine

    Multisoliton solutions and integrability aspects of coupled nonlinear Schrodinger equations

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    Using Painleve singularity structure analysis, we show that coupled higher-order nonlinear Schrodinger (CHNLS) equations admit Painleve property. Using the results of Painleve analysis, we succeed in Hirota bilinearizing the CHNLS equations, one soliton and two soliton solutions are explictly obtained. Lax pairs are explictly constructed.Comment: Eight pages and six figures. Physical Review E (to be appear

    MRI Guided Interventions needs new materials and contrast agents

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    Abstract Magnetic resonance imaging (MRI) is primary a diagnostic tool, with or without the use of contrast agents. To enable the use of MRI for interventional purposes, devices are needed that are nonmagnetic and non-conductive and visible in MRI. Fiber-composite materials provide enough strength to replace classic metal-based devices, and at the same time provide opportunity to include contrast agents as part of the matrix. Gadolinium chelates are clinically being used ad contrast agents by delivery into the vascular space, and then diffusing into the site (tumor, scar, vessel) of interest, Apart from incomplete diffusion, they are rapidly washed out of the site, and some gadolinium chelates cause specific renal toxicity Porphyrins are potential MR contrast agents, considering their stable form within chelate complexes that comprises paramagnetic metal ions and their retention by the site selectively The present study aims to evaluate the site enhancing imaging characteristics of novel metalloporphyrin derivatives. In this project we investigate the MRI characteristics of metalloporphyrin derivatives as potential biocompatible MR contrast agent. However, to enable this several technical issues have to be resolved. Hemin is sparingly soluble in aqueous media. Therefore, derivatives of Hemin have been processed for enhancing the solubility as PEGylated Hemin, Hemin Arginate or Hemin Lysinate. This new contrast agent has achieved a high molar Relaxivity in MRI allowing decrease of the required dose for in vivo applications. These derivatives suggest that the size, geometry, and polarity of hemin can be modified to optimize their relaxivities ,pharmacokinetic properties, and biocompatibility

    Thin accretion disk signatures of slowly rotating black holes in Ho\v{r}ava gravity

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    In the present work, we consider the possibility of observationally testing Ho\v{r}ava gravity by using the accretion disk properties around slowly rotating black holes of the Kehagias-Sfetsos solution in asymptotically flat spacetimes. The energy flux, temperature distribution, the emission spectrum as well as the energy conversion efficiency are obtained, and compared to the standard slowly rotating general relativistic Kerr solution. Comparing the mass accretion in a slowly rotating Kehagias-Sfetsos geometry in Ho\v{r}ava gravity with the one of a slowly rotating Kerr black hole, we verify that the intensity of the flux emerging from the disk surface is greater for the slowly rotating Kehagias-Sfetsos solution than for rotating black holes with the same geometrical mass and accretion rate. We also present the conversion efficiency of the accreting mass into radiation, and show that the rotating Kehagias-Sfetsos solution provides a much more efficient engine for the transformation of the accreting mass into radiation than the Kerr black holes. Thus, distinct signatures appear in the electromagnetic spectrum, leading to the possibility of directly testing Ho\v{r}ava gravity models by using astrophysical observations of the emission spectra from accretion disks.Comment: 12 pages, 15 figures. V2: 13 pages, clarifications and discussion added; version accepted for publication in Classical and Quantum Gravit

    Testing gravitational-wave searches with numerical relativity waveforms: Results from the first Numerical INJection Analysis (NINJA) project

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    The Numerical INJection Analysis (NINJA) project is a collaborative effort between members of the numerical relativity and gravitational-wave data analysis communities. The purpose of NINJA is to study the sensitivity of existing gravitational-wave search algorithms using numerically generated waveforms and to foster closer collaboration between the numerical relativity and data analysis communities. We describe the results of the first NINJA analysis which focused on gravitational waveforms from binary black hole coalescence. Ten numerical relativity groups contributed numerical data which were used to generate a set of gravitational-wave signals. These signals were injected into a simulated data set, designed to mimic the response of the Initial LIGO and Virgo gravitational-wave detectors. Nine groups analysed this data using search and parameter-estimation pipelines. Matched filter algorithms, un-modelled-burst searches and Bayesian parameter-estimation and model-selection algorithms were applied to the data. We report the efficiency of these search methods in detecting the numerical waveforms and measuring their parameters. We describe preliminary comparisons between the different search methods and suggest improvements for future NINJA analyses.Comment: 56 pages, 25 figures; various clarifications; accepted to CQ

    Towards good practice guidelines for the contour method of residual stress measurement

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    Accurate measurement of residual stress in metallic components using the contour method relies on the achievement of a good quality cut, on the appropriate measurement of the deformed cut surface and on the robust analysis of the measured data. There is currently no published standard or code of practice for the contour method. As a first step towards such a standard, this study draws on research investigations addressing the three main steps in the method: how best to cut the specimens; how to measure the deformation contour of the cut surface; and how to analyse the data. Good practice guidance is provided throughout the text accompanied by more detailed observations and advice tabulated in Appendi

    Understanding mixed sequence DNA recognition by novel designed compounds: the kinetic and thermodynamic behavior of azabenzimidazole diamidines

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    Sequence-specific recognition of DNA by small organic molecules offers a potentially effective approach for the external regulation of gene expression and is an important goal in cell biochemistry. Rational design of compounds from established modules can potentially yield compounds that bind strongly and selectively with specific DNA sequences. An initial approach is to start with common A·T bp recognition molecules and build in G·C recognition units. Here we report on the DNA interaction of a synthetic compound that specifically binds to a G·C bp in the minor groove of DNA by using an azabenzimidazole moiety. The detailed interactions were evaluated with biosensor-surface plasmon resonance (SPR), isothermal calorimetric (ITC), and mass spectrometry (ESI-MS) methods. The compound, DB2277, binds with single G·C bp containing sequences with subnanomolar potency and displays slow dissociation kinetics and high selectivity. A detailed thermodynamic and kinetic study at different experimental salt concentrations and temperatures shows that the binding free energy is salt concentration dependent but essentially temperature independent under our experimental conditions, and binding enthalpy is temperature dependent but salt concentration independent. The results show that in the proper compound structural context novel heterocyclic cations can be designed to strongly recognize complex DNA sequences

    Treatment of two postoperative endophthalmitis cases due to Aspergillus flavus and Scopulariopsis spp. with local and systemic antifungal therapy

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    <p>Abstract</p> <p>Background</p> <p>Endophthalmitis is the inflammatory response to invasion of the eye with bacteria or fungi. The incidence of endophthalmitis after cataract surgery varies between 0.072–0.13 percent. Treatment of endophthalmitis with fungal etiology is difficult.</p> <p>Case Presentation</p> <p><b>Case 1: </b>A 71-year old male diabetic patient developed postoperative endophthalmitis due to <it>Aspergillus flavus</it>. The patient was treated with topical amphotericin B ophthalmic solution, intravenous (IV) liposomal amphotericin-B and caspofungin following vitrectomy.</p> <p><b>Case 2: </b>A 72-year old male cachectic patient developed postoperative endophthalmitis due to <it>Scopulariopsis </it>spp. The patient was treated with topical and IV voriconazole and caspofungin.</p> <p>Conclusion</p> <p><it>Aspergillus </it>spp. are responsible of postoperative fungal endophthalmitis. Endophthalmitis caused by <it>Scopulariopsis </it>spp. is a very rare condition. The two cases were successfully treated with local and systemic antifungal therapy.</p

    Robust water repellent ZnO nanorod array by Swift Heavy Ion Irradiation: Effect of Electronic Excitation Induced Local Chemical State Modification

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    Tailoring the surface properties by varying the chemistry and roughness could be of interest for self-cleaning applications. We demonstrate the transformation of hydrophobic ZnO Nano rod (NR) array into superhydrophobic nature by changing the local chemical state and without altering the surface roughness by swift heavy ion (SHI) irradiation. The aligned ZnO NR arrays were irradiated using 150 MeV Ag ions with different fluences from 5E10 to 3E12 ions/cm2. The observed static water contact angles of ZnO NRs samples were 103° ± 3°, 152° ± 4°,161° ± 3°, 164° ± 2°, 167° ± 2°,154 ± 3° and 151° ± 2° for the pristine, ion fluencies of 1E11, 3E11, 5E11, 7E11, 1E12 and 3E12 ions cm−2, respectively. The change in local surface chemistry via formation of surface oxygen related defects due to electronic excitations induced by ion irradiation determine the water dewetting properties. It is found that surface oxygen related defects could be tuned by varying the fluence of the SHIs. Durability tests show that the SHI induced surface oxygen-deficient ZnO NRs have the stable superhydrophobic behavior for more than a year
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