Dysphagia due to diffuseidiopathic skeletal hyperostosis (DISH): case report

Diffuse idiopathic skeletal hyperostosis (DISH) or Forestier's disease isa form of degenerative arthritiswith unique spinal and extra spinal manifestations. Dysphagia due to DISH is uncommon but when present DISH should be suspected. Surgical decompression can relieve some of the symptoms. We report a case of a 60 year old male with progressive dysphagia, hoarseness of voice and fixed neck flexion. Imaging studies showed flowing osteophytes of the cervical and thoracic spines. Anterior decompression of the osteophytes at C3/4 was done to relieve the dysphagia with good outcome

Basilar Invagination: A Case Review

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An isolated superior sternal cleft in a neonate in western Kenya: case report

Sternal cleft is a rare congenital anomaly and very few cases have been described especially in Africa. This is a case of an isolated superior sternal cleft in a term neonate in Western Kenya

Thermal Analysis of Polyamide-66/POSS nanocomposite fiber

Poly Hexamethylene Adipamide (PA-66) nanocomposite fibers were prepared by melt mixing PA-66 using two Polyhedral Oligomeric Silsesquioxane (POSS) as fillers: Octaphenyl Polyhedral Oligomeric Silsesquioxane (OPS) and Octa-Aminophenyl Polyhedral Oligomeric Silsesquioxane (OAPS). OPS and OAPS in PA-66 was varied between 1% wt. and 3% wt. PA-66 nanocomposite fibers with varying concentrations of POSS were then analyzed using TGA, DSC and then compared to that of neat PA-66. PA-66 was thermally stable up to 350°C with low molecular weight species burning off below 200°C. PA-66-OPS were also thermally stable up to 350°C with burn-off of low molecular weight species being below 240°C. PA-66-OAPS was found to be more thermally stable (up to 400°C) with low molecular weight species burning off below 200°C. The decomposition temperatures of the PA66/POSS nanocomposites increased as the POSS content was increased, an indicator that the thermal decay of the PA66/POSS nanocomposites was slowed down by incorporating POSS into the PA66 matrix. Addition of POSS to PA-66 also increased crystallization temperature but did not change the melting temperatures. OAPS exhibited better thermal behavior when added to PA-66 compared to OPS and therefore is recommended as a prospective nanomaterial for further studies

Continuous Invasion by Respiratory Viruses Observed in Rural Households During a Respiratory Syncytial Virus Seasonal Outbreak in Coastal Kenya.

BACKGROUND: Households are high-intensity close-contact environments favorable for transmission of respiratory viruses, yet little is known for low-income settings. METHODS: Active surveillance was completed on 47 households in rural coastal Kenya over 6 months during a respiratory syncytial virus (RSV) season. Nasopharyngeal swabs (NPSs) were taken from 483 household members twice weekly irrespective of symptoms. Using molecular diagnostics, NPSs from 6 households were screened for 15 respiratory viruses and the remainder of households only for the most frequent viruses observed: rhinovirus (RV), human coronavirus (HCoV; comprising strains 229E, OC43, and NL63), adenovirus (AdV), and RSV (A and B). RESULTS: Of 16928 NPSs tested for the common viruses, 4259 (25.2%) were positive for ≥1 target; 596 (13.8%) had coinfections. Detection frequencies were 10.5% RV (1780), 7.5% HCoV (1274), 7.3% AdV (1232), and 3.2% RSV (537). On average, each household and individual had 6 and 3 different viruses detected over the study period, respectively. Rhinovirus and HCoV were detected in all the 47 households while AdV and RSV were detected in 45 (95.7%) and 40 (85.1%) households, respectively. The individual risk of infection over the 6-month period was 93.4%, 80.1%, 71.6%, 61.5%, and 37.1% for any virus, RV, HCoV, AdV, and RSV, respectively. NPSs collected during symptomatic days and from younger age groups had higher prevalence of virus detection relative to respective counterparts. RSV was underrepresented in households relative to hospital admission data. CONCLUSIONS: In this household setting, respiratory virus infections and associated illness are ubiquitous. Future studies should address the health and economic implications of these observations

Identification of schistosome-infected snails by detecting schistosomal antigens and DNA sequences

Cercarial shedding tests do not provide species identification of the schistosomes concerned and cannot detect prepatent schistosomal infections. We have demonstrated that both immunodetection by ELISA of schistosomal antigens in snail hemolymph, and dot hybridization of snail extracts by a DNA probe representing highly repeated sequences, proved suitable for detecting infected snails during prepatency as well as patency. A group-specific monoclonal antibody was found to be suitable for detecting Schistosoma mansoni infection in Biomphalaria sp., but not for positive identification of S. haematobium in Bulinus sp. Comparative evaluation of the diagnostic qualities, and technical aspects and cost of these tests, point to the superiority of the immunodetection approach for large scale detection of snails prepatently infected with S. mansoni. This approach is potentially useful for providing extended information on schistosome-snail epidemiology that may facilitate rapid evaluation of the danger of post-control reinfection, and help make decisions on the time and place of supplementary control measures. In this context the potential usefulness of the immunodetection or DNA probing approach for facilitating catalytic model representation of schistosome-snail epidemiology warrants further evaluation. Specific identification of S. haematobium in Bulinus by either of these approaches may be possible depending on the development of suitable antibodies or DNA probes

Sorghum production practices in an integrated crop-livestock production system in Makueni county, eastern Kenya

Productivity of sorghum has been below potential in arid and semi-arid lands of Kenya, due to poor agronomic practices and soil nutrient deficiency. Sorghum crop is fairly drought tolerant, resistant to waterlogging, and yields are reasonably better in infertile soils compared to other crops. Proper agronomic practices would significantly increase yields as well as nutrient content in grains and crop residues used as livestock feed. The objective of this study was to investigate the existing sorghum production practices and sorghum use as food and feed sources. A survey involving 90 farmers from sorghum producing areas in Makueni County was conducted. The survey focused on the varieties and fertilizers used, trends in yields, constraints to sorghum production and the present strategies used for sorghum as animal feed. Most farmers (84.4%) used uncertified seeds from own saved sources, and the commonly grown variety was Seredo (44.5%) due to resistance to bird damage. The majority (32.1%) of farmers recorded very low yield of sorghum grain, from151 to 250 kg ha-1. Most farmers (68.9%) used farmyard manure in sorghum production, while 30.9% of the farmers did not use any fertilizer. All farmers indicated that their greatest challenge in sorghum production was inadequate rainfall. Bird damage to the crop was a chronic problem to most (73.3%) farmers. The majority (58.9%) of farmers conserved sorghum residue for feed as hay. The findings show the need to provide technical information and guidance on the production practices, such as choosing best-yielding seed varieties, proper methods of pest and disease control and proper use and conservation of sorghum residue as animal feed

Effects of Mega Dose Micronutrient Supplementation On Serum Zinc, Retinol and Immune Status of Adult Males and Females Diagnosed with and Without HIV, Malaria and TB in Western Kenya – An Unpublished Perspective as at The Year 2004

Background: The role of micronutrients in management of HIV/AIDS, malaria and TB remains poorly understood worldwide. Objectives: To assess differences in mega dose nutritional management between HIV-seronegative and seropositive adult males and females diagnosed with HIV at Voluntary Testing and Counseling Centers (VCT) in Western Kenya. Methods: This was a randomized controlled study in which 90 subjects were recruited on the basis of an HIV-seropositive result from a voluntary and counseling center (VCT) using rapid HIV test kits. They were evaluated at baseline and every 4 weeks for 3 months to establish their clinical, biochemical and immunological status. After 12 weeks, 74 clients were still in the study, 9 were lost to follow-up while 7 had died. Of the 74 who completed the study, confirmation of baseline HIV status by ELIZA revealed that 63 were HIV-seropositive while 11 were HIV-seronegative despite losing spouses to HIV/AIDS. Correlations between parameters at baseline, during and after intervention were determined; Spearman’s Rho Coefficients indicating the level of significance. Group means were used to compare continuous data while categorical data was compared using Chi-Square. Results: Significant reductions in the clinical manifestation of disease were noted in the cohort after intervention for 12 weeks. Despite the large and different micronutrient dosages used between the two study arms, the only difference by arm of intervention was in the serum vitamin E level at 4 weeks which was much higher in arm 1 than it was in arm 2 of the study (p = 0.005). This might have been occasioned by the significant repletion of zinc in both arms, probably because use of citric acid in both arms improved zinc up-take from the supplements, food and/or reserves enabling other nutrients to be appropriately restored in both arms, these supporting the decision to pool the study arms and compare differences by HIV-seronegative and seropositive, notwithstanding the small sample sizes recruited but which nonetheless were our study limitation. Independent of the intervention arms, reduction of viral load by more than 0.5 log10 copies/ml correlated with higher baseline optical densities of HIV antibodies (P = 0.016) and higher baseline viral loads (p = 0.0001). A lower optical density of HIV antibodies at baseline correlated with higher serum zinc levels at 12 weeks (p = 0.008) and a lower Body Mass Index (BMI) at baseline (p = 0.029). Independent of the arm of study, a significant increase in CD4 cells counts post intervention correlated with lower baseline viral loads (p = 0.010), lower baseline NK cell counts (p = 0.007

International Perspectives on Nonformal Education

The New England Regional Meeting of the Comparative and International Education Society was held on the campus of the University of Massachusetts, Amherst, on 3 May, 1979. The conference was co-sponsored by the Division of Community Education, Springfield College, and the Center for International Education, School of Education, University of Massachusetts. The theme of the conference was International Perspectives on Nonformal Education. The papers delivered ranged in topics from the use of traditional art forms and poetry as a medium of nonformal education to the discussion of the philosophical foundations underlying the field. Case studies of specific nonformal education projects helped to highlight the conference. A total fifteen papers were delivered, all of which are included in their original form in this document. The papers represent the views of the authors and not necessarily those of the organizers