203 research outputs found
Optical Sum Rule anomalies in the High-Tc Cuprates
We provide a brief summary of the observed sum rule anomalies in the
high-T cuprate materials. A recent issue has been the impact of a
non-infinite frequency cutoff in the experiment. In the normal state, the
observed anomalously high temperature dependence can be explained as a `cutoff
effect'. The anomalous rise in the optical spectral weight below the
superconducting transition, however, remains as a solid experimental
observation, even with the use of a cutoff frequency.Comment: 4 pages, 2 figures, very brief review of optical sum rule anomal
Kinetic Energy, Condensation Energy, Optical Sum Rule and Pairing Mechanism in High-Tc Cuprates
The mechanism of high-Tc superconductivity is investigated with interests on
the microscopic aspects of the condensation energy. The theoretical analysis is
performed on the basis of the FLEX approximation which is a microscopic
description of the spin-fluctuation-induced-superconductivity. Most of phase
transitions in strongly correlated electron system arise from the correlation
energy which is copmetitive to the kinetic energy. However, we show that the
kinetic energy cooperatively induces the superconductivity in the underdoped
region. This unusual decrease of kinetic energy below T_c is induced by the
feedback effect. The feedback effect induces the magnetic resonance mode as
well as the kink in the electronic dispersion, and alters the properties of
quasi-particles, such as mass renormalization and lifetime. The crossover from
BCS behavior to this unusual behavior occurs for hole dopings. On the other
hand, the decrease of kinetic energy below T_c does not occur in the
electron-doped region. We discuss the relation to the recent obserbation of the
violation of optical sum rule
Optical Sum Rule in Finite Bands
In a single finite electronic band the total optical spectral weight or
optical sum carries information on the interactions involved between the charge
carriers as well as on their band structure. It varies with temperature as well
as with impurity scattering. The single band optical sum also bears some
relationship to the charge carrier kinetic energy and, thus, can potentially
provide useful information, particularly on its change as the charge carriers
go from normal to superconducting state. Here we review the considerable
advances that have recently been made in the context of high oxides, both
theoretical and experimental.Comment: Review article accepted for publication in J. Low Temp. Phys. 29
pages, 33 figure
Superconducting Fluctuation and Pseudogap in Disordered Short Coherence Length Superconductor
We investigate the role of disorder on the superconducting (SC) fluctuation
in short coherence length d-wave superconductors. The particular intetest is
focused on the disorder-induced microscopic inhomogeneity of SC fluctuation and
its effect on the pseudogap phenomena. We formulate the self-consistent 1-loop
order theory for the SC fluctuation in inhomogeneous systems and analyze the
disordered -- model. The SC correlation function, electronic DOS and
the critical temperature are estimated. The SC fluctuation is localized like a
nanoscale granular structure when the coherence length is short, namely the
transition temperature is high. This is contrasted to the long coherence length
superconductors where the order parameter is almost uniform in the microscopic
scale. In the former case, the SC fluctuation is enhanced by the disorder in
contrast to the Abrikosov-Gorkov theory. These results are consistent with the
STM, NMR and transport measurements in high- cuprates and illuminate
the essential role of the microscopic inhomogeneity. We calculate the spacial
dependence of DOS around the single impurity and discuss the consistency with
the NMR measurements
Phonons and related properties of extended systems from density-functional perturbation theory
This article reviews the current status of lattice-dynamical calculations in
crystals, using density-functional perturbation theory, with emphasis on the
plane-wave pseudo-potential method. Several specialized topics are treated,
including the implementation for metals, the calculation of the response to
macroscopic electric fields and their relevance to long wave-length vibrations
in polar materials, the response to strain deformations, and higher-order
responses. The success of this methodology is demonstrated with a number of
applications existing in the literature.Comment: 52 pages, 14 figures, submitted to Review of Modern Physic
Engineering the isobutanol biosynthetic pathway in Escherichia coli by comparison of three aldehyde reductase/alcohol dehydrogenase genes
Biofuels synthesized from renewable resources are of increasing interest because of global energy and environmental problems. We have previously demonstrated production of higher alcohols from Escherichia coli using a 2-keto acid-based pathway. Here, we have compared the effect of various alcohol dehydrogenases (ADH) for the last step of the isobutanol production. E. coli has the yqhD gene which encodes a broad-range ADH. Isobutanol production significantly decreased with the deletion of yqhD, suggesting that the yqhD gene on the genome contributed to isobutanol production. The adh genes of two bacteria and one yeast were also compared in E. coli harboring the isobutanol synthesis pathway. Overexpression of yqhD or adhA in E. coli showed better production than ADH2, a result confirmed by activity measurements with isobutyraldehyde
Tyrosine kinase inhibitors reprogramming immunity in renal cell carcinoma: rethinking cancer immunotherapy
Review article[Abstract] The immune system regulates angiogenesis in cancer by way of both pro- and antiangiogenic activities. A bidirectional link between angiogenesis and the immune system has been clearly demonstrated. Most antiangiogenic molecules do not inhibit only VEGF signaling pathways but also other pathways which may affect immune system. Understanding of the role of these pathways in the regulation of immunosuppressive mechanisms by way of specific inhibitors is growing. Renal cell carcinoma (RCC) is an immunogenic tumor in which angiogenesis and immunosuppression work hand in hand, and its growth is associated with impaired antitumor immunity. Given the antitumor activity of selected TKIs in metastatic RCC (mRCC), it seems relevant to assess their effect on the immune system. The confirmation that TKIs improve cell cytokine response in mRCC provides a basis for the rational combination and sequential treatment of TKIs and immunotherapy
Formation of a N2-dG:N2-dG Carbinolamine DNA Cross-link by the trans-4-Hydroxynonenal-Derived (6S,8R,11S) 1,N2-dG Adduct
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