Sensemaking processes during the first months of COVID-19 pandemic: Using diaries to deepen how Italian youths experienced lockdown measures

The COVID-19 pandemic has brought about disruptive changes in individuals’ lives, breaking the established systems of meaning worldwide. Indeed, in the first months of the pandemic, with individuals being forced to stay at home for a prolonged time to contain the spread of the virus, the need to build new meanings to understand and face this crisis emerged. Building on this, the present study contributes to the understanding of how sensemaking processes were shaped in the face of COVID-19 collective trauma during the very first months of the pandemic. Hence, 36 Italian young adults aged between 21 and 25 submitted daily diary entries for two weeks (T1 was the third week of Italian National lockdown; T2 was the penultimate week before the ease of such stay-at-home orders), resulting in 504 texts. The stimulus was always “Could you describe your daily experience and feelings?”. The Grounded Theory was used. Thus, 15 categories emerged, grouped into three macro-categories. The core category was sensemaking as adaptation. Indeed, the sensemaking process seemed to be a strategy to adapt to the new circumstances related to the lockdown, facing the emotional, cognitive, and activation reactions such conditions by relying on coping strategies and the redefinition of primary as well as broader social relationships

Green manure and compost effects on n-p dynamics in mediterranean organic stockless systems

Stockless systems, where plant and animal production are uncoupled, represent a common condition in Mediterranean areas. In organic systems, soil fertility is mainly managed by green manures, whereas composts of plant origin represent suitable soil conditioners. The low P content of these materials, together with the shortage of animal waste availability, determine potential nutrient depletion overtime and, in calcareous soils, P mining conditions. In a two-year field experiment in Central Italy, the effect of green manure vetch (Vicia villosa) (GM+) was compared with a control left fallow (GM-), combined with P-based fertilizers (F) on organic maize (Zea mays). Yields and N-P dynamics were evaluated by direct measurements, nutrient balance and efficiency index. N balance was higher than in GM+ GM- (+71.8 and -23.6 kg N ha-1, respectively). P enriched compost with RP (rock-phosphate) (EP), showed significant improvement in P use efficiency (meanly +34%) than other treatments (unfertilized control (RP), not P enriched compost (NEP)) and P equilibrium in the short run. On the other hand, P-fertilizers and maize residues soil incorporation determined P surplus in a long perspective (up to +10 kg P ha-1). Results emphasize the possibility of P reintegration in stockless organic systems without animal wastes

Numerical simulation of a complete charging-discharging phase of a shell and tube thermal energy storage with phase change material

Abstract Numerical simulations of a shell and tube energy storage device based on a phase change material (PCM) in vertical position are performed. The heat transfer fluid (HTF) is a diathermic oil and the PCM, made by molten salts, is confined within a closed shell surrounding the tube where the HTF flows. The energy loss through the external wall is included. The test has been carried out within the experimental activity performed by ENEA. A complete cycle is considered: the initial stabilization, the charging phase and the discharging phase. Details of flow behavior within the molten PCM are described highlighting its influence on the device performance

Organic vs. organic - soil arthropods as bioindicators of ecological sustainability in greenhouse system experiment under Mediterranean conditions

Organic greenhouse (OGH) production is characterized by different systems and agricultural practices with diverse environmental impact. Soil arthropods are widely used as bioindicators of ecological sustainability in open field studies, while there is a lack of research on organic production for protected systems. This study assessed the soil arthropod abundance and diversity over a 2-year crop rotation in three systems of OGH production in the Mediterranean. The systems under assessment differed in soil fertility management: SUBST - a simplified system of organic production, based on an input substitution approach (use of guano and organic liquid fertilizers), AGROCOM - soil fertility mainly based on compost application and agroecological services crops (ASC) cultivation (tailored use of cover crops) as part of crop rotation, and AGROMAN - animal manure and ASC cultivation as part of crop rotation. Monitoring of soil fauna was performed by using pitfall traps and seven taxa were considered: Carabidae, Staphylinidae, Araneae, Opiliones, Isopoda, Myriapoda, and Collembola. Results demonstrated high potential of ASC cultivation as a technique for beneficial soil arthropod conservation in OGH conditions. SUBST system was dominated by Collembola in all crops, while AGROMAN and AGROCOM had more balanced relative abundance of Isopoda, Staphylinidae, and Aranea. Opiliones and Myriapoda were more affected by season, while Carabidae were poorly represented in the whole monitoring period. Despite the fact that all three production systems are in accordance with the European Union regulation on organic farming, findings of this study displayed significant differences among them and confirmed the suitability of soil arthropods as bioindicators in protected systems of organic farming

Infantile/congenital high-grade gliomas: molecular features and therapeutic perspectives

Brain tumors in infants account for less than 10% of all pediatric nervous system tumors. They include tumors diagnosed in fetal age, neonatal age and in the first years of life. Among these, high-grade gliomas (HGGs) are a specific entity with a paradoxical clinical course that sets them apart from their pediatric and adult counterparts. Currently, surgery represents the main therapeutic strategy in the management of these tumors. Chemotherapy does not have a well-defined role whilst radiotherapy is rarely performed, considering its late effects. Information about molecular characterization is still limited, but it could represent a new fundamental tool in the therapeutic perspective of these tumors. Chimeric proteins derived from the fusion of several genes with neurotrophic tyrosine receptor kinase mutations have been described in high-grade gliomas in infants as well as in neonatal age and the recent discovery of targeted drugs may change the long-term prognosis of these tumors, along with other target-driven therapies. The aim of this mini review is to highlight the recent advances in the diagnosis and treatment of high-grade gliomas in infants with a particular focus on the molecular landscape of these neoplasms and future clinical applications

Vemurafenib treatment of pleomorphic xanthoastrocytoma in a child with Down syndrome

Brain tumors are the most common solid neoplasms of childhood, but they are very rarely reported in children with Down Syndrome (DS), who develop more commonly different types of malignancies. In particular, we hereby report the case of an 8-years-old child with DS that presented to our attention for neurological and endocrinological issues. Brain imaging revealed the presence of a mass that was partially resected revealing a histological diagnosis of Pleomorphic Xanthoastrocytoma (PXA), a rare WHO grade II tumor extending from the diencephalic region into the surrounding brain tissue. These tumors can harbor the BRAF mutation p.V600E, targetable by the specific inhibitor Vemurafenib. After confirming the presence of the mutation in the tumor, the patient was treated with Vemurafenib. The treatment proved to be effective, leading to a partial response and a stabilization of the disease. Usually, in patients with DS a reduction of the dose of chemotherapeutic drugs is necessary. Vemurafenib was instead well-tolerated as the only observed adverse effect was grade I skin toxicity. This is, to our knowledge, the first case of a PXA reported in a child with DS and the first DS patient treated with Vemurafenib

Analisi di fitotossicità e impiego di sansa umida denocciolata in una rotazione farro-cece in regime di agricoltura biologica

Pratiche di agricoltura intensiva hanno condotto alla degradazione della risorsa suolo, vale a dire ne hanno diminuito la qualità. Più precisamente, la degradazione riguarda la riduzione della sostanza organica, della stabilità strutturale e della disponibilità di nutrienti nel suolo, con conseguente decremento della produttività. All’interno di un progetto di ricerca in corso, relativo a produzione e impiego di compost in agricoltura biologica, sono previste analisi di fitotossicità su sansa umida denocciolata (SD) poi impiegata in una rotazione farro-cece. L’obiettivo della ricerca è quello di verificare come l’incorporazione al suolo di matrici organiche (M), anche tal quali, può concorrere a mantenere o incrementare la fertilità del suolo ed a sostenere i livelli produttivi delle colture. Nelle analisi di fitotossicità su SD, effettuate con specie test Lepidium sativum L., sono state saggiate oltre alle consuete concentrazioni dell’estratto (50% e 75%), indicate nelle metodiche ufficiali, anche una diluizione maggiore pari al 25% e SD tal quale (100%) centrifugata e filtrata. In una rotazione biennale cece da granella - farro, effettuata a Foggia (campo sperimentale del CRA-SCA) nell’annata agraria 2007-2008, sono stati posti a confronto per ciascuna coltura i seguenti trattamenti: SD tal quale; fertilizzante organo-minerale (OM) ammesso in biologico; controllo non fertilizzato (C). I risultati dei saggi di fitotossicità indicano che la M in esame è risultata fitotossica essendo stato riscontrato un indice di germinazione (Ig) del 44,4%. Dall’esame degli indici calcolati per ciascuna diluizione, inoltre, si è evidenziato come al diminuire della stessa (25%>50%>75%>100%) aumenta l’inibizione all’emergenza e alla crescita radicale (Ig: 66,2%>55,2%>46,9%>9,2%), fino al valore minimo di Ig riscontrato per SD tal quale. Infine, è emerso che la tossicità si esercita a livello di percorsi metabolici diversi, con una netta prevalenza degli effetti sulla lunghezza radicale piuttosto che sul numero di semi germinati. I risultati ottenuti nella prova agronomica hanno evidenziato per il cece una maggiore produzione di granella con OM (2,5 t ha-1) rispetto al trattamento SD (2,1 t ha-1), mentre i valori rilevati per i residui sono paragonabili tra le tre tesi. Le produzioni di granella ottenute per il farro risultano confrontabili, mentre la produzione di paglia è stata maggiore con OM (3,4 e 2,9 t ha-1 rispettivamente per OM e per SD). Da questa attività di ricerca è emerso che SD è una matrice particolare relativamente agli effetti sulle colture, che dovrebbe essere stabilizzata e maturare grazie ad attività di biodegradazione (e quindi compostata in miscela con altre matrici) per poter influenzare positivamente la fertilità del suolo e la produttività delle colture

Magnetic resonance imaging for deep infiltrating endometriosis: current concepts, imaging technique and key findings

Endometriosis is an estrogen-dependent chronic disease affecting about 10% of reproductive-age women with symptoms like pelvic pain and infertility. Pathologically, it is defined by the presence of endometrial tissue outside the uterine cavity responsible for a chronic inflammatory process. For decades the diagnosis of endometriosis was based on surgical exploration and biopsy of pelvic lesions. However, laparoscopy is not a risk-free procedure with possible false negative diagnosis due to an underestimate of retroperitoneal structures such as ureters and nerves. For these reasons nowadays, the diagnosis of endometriosis is based on a noninvasive approach where clinical history, response to therapy and imaging play a fundamental role. Trans-vaginal ultrasound and magnetic resonance imaging are suitable for recognizing most of endometriotic lesions; nevertheless, their accuracy is strictly determined by operators’ experience and imaging technique. This review paper aims to make radiologists aware of the diagnostic possibilities of pelvic MRI and familial with the MR acquisition protocols and image interpretation for women with endometriosis

The multifaceted covid-19: Ct aspects of its atypical pulmonary and abdominal manifestations and complications in adults and children. a pictorial review

Our daily experience in a COVID hospital has allowed us to learn about this disease in many of its changing and unusual aspects. Some of these uncommon manifestations, however, appeared more frequently than others, giving shape to a multifaceted COVID-19 disease. This pictorial review has the aim to describe the radiological aspects of atypical presentations and of some complications of COVID-19 disease in adults and children and provide a simple guide for radiologists to become familiar with the multiform aspects of this disease