Magnetic properties of the strongly interacting matter

We study the magnetic properties of the strongly interacting matter using Lattice QCD simulations. The QCD medium shows a paramagnetic behavior in the range of temperatures 100–400 MeV, with a sharp increase of the magnetic susceptibility above the deconfinement temperature. We expect a significant magnetic contribution to the pressure of the system in non-central heavy-ion collisions

Anisotropy of the QQ potential in a magnetic field

We study how the static quark-antiquark potential for Nf = 2+1 QCD at the physical point gets modified by the presence of a constant and uniform magnetic field. We observe an anisotropy to appear in the potential: it gets steeper in the directions transverse to the magnetic field than in the longitudinal one. By comparing to the case with zero magnetic field, we show that the string tension increases (decreases) in the perpendicular (parallel) direction, while the absolute value of the Coulomb coupling and the Sommer parameter show the opposite behavior

Experimental results of a national technical assessment procedure on commercial FRP for structural strengthening: wet-lay-up systems

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Arsenic trioxide (ATO) and MEK1 inhibition synergize to induce apoptosis in acute promyelocytic leukemia cells

Recent studies suggest that components of the prosurvival signal transduction pathways involving the Ras-mitogen-activated protein kinase ( MAPK) can confer an aggressive, apoptosis-resistant phenotype to leukemia cells. In this study, we report that acute promyelocytic leukemia (APL) cells exploit the Ras-MAPK activation pathway to phosphorylate at Ser112 and to inactivate the proapoptotic protein Bad, delaying arsenic trioxide (ATO)-induced apoptosis. Both in APL cell line NB4 and in APL primary blasts, the inhibition of extracellular signal-regulated kinases 1/2 (ERK1/2) and Bad phosphorylation by MEK1 inhibitors enhanced apoptosis in ATO-treated cells. We isolated an arsenic-resistant NB4 subline (NB4-As-R), which showed stronger ERK1/2 activity (2.7-fold increase) and Bad phosphorylation (2.4-fold increase) compared to parental NB4 cells in response to ATO treatment. Upon ATO exposure, both NB4 and NB4-As-R cell lines doubled protein levels of the death antagonist Bcl-xL, but the amount of free Bcl-xL that did not heterodimerize with Bad was 1.8-fold greater in NB4-As-R than in the parental line. MEK1 inhibitors dephosphorylated Bad and inhibited the ATO-induced increase of Bcl-xL, overcoming ATO resistance in NB4-As-R. These results may provide a rationale to develop combined or sequential MEK1 inhibitors plus ATO therapy in this clinical setting

Adverse events in thyroid surgery: observational study in three surgical units with high volume/year

Background: Thyroid surgery, performed for benign or malignant pathologies, is one of the most frequently performed procedures and its frequency has even been increasing in recent years. Postoperative bleeding, recurrent laryngeal nerve (RLN) palsy, associated to dysphonia, dysphagia, dyspnea, and hypoparathyroidism represent the most fearful and common complications. We conducted a multicenter, observational study of retrospectively collected data in three high-volume referral centers, enrolling all patients undergone to thyroid surgery between January 2016 and December 2017 in Parma University Hospital, Cagliari University Hospital and Ferrara University Hospital. Materials: Patients were divided into five groups, differentiated thyroid carcinoma, medullary thyroid carcinoma, non-toxic benign pathology, hyperfunctioning benign pathology and NIFTP (Non-invasive Follicular Thyroid neoplasm with Papillary-like nuclear features). A follow up at 7 and 30 days was executed, evaluating the onset of paresthesia, dysphonia and dysphagia. A 6-month follow-up was conducted in cases of early complications. Results: Totally, 1252 patients were eligible for the study: 907 female and 345 male, with a female to male ratio of 2.6:1 and an average age of 53.428. Total thyroidectomy was performed in 1022 cases, lobectomy in 230. After 6 months we recorded paresthesia in 0.5%, dysphonia in 1.8% and dysphagia in 0.5%. Conclusion: Our study confirms once again that a share of morbidity escapes the possibilities of prediction and control by the operator, depending on patient anamnestic, pathological or anatomical factors

Magnetic properties of the QCD medium

We present our study of the QCD medium magnetic properties. We use N f = 2+1 quark flavors QCD at the physical point, with Symanzik tree level improved gauge action and stout improved staggered fermions. We find that the strongly interacting matter behaves as a paramagnet in the range of temperatures (100− 400) MeV, with a sharp increase of the magnetic susceptibiliy at the deconfinement crossover. For magnetic field values expected during off-central heavy ion collisions, we found that the magnetic contribution to the pressure can reach up to the 40% of the total pressure near the crossover transition. Finally we discuss preliminary results on higher order magnetic contributions to the free energy