339 research outputs found
Photosynthetic responses of Amygdalus arabica Olivier and Atriplex canescens (Pursh) Nutt. to drought stress under field conditions
The central Anatolian region of Turkey is exposed to increasing temperatures and severe drought stress. Due to aridity and desertification brought about by global warming, climate change and overutilization, plant species in these regions are under the risk of extinction. Thus, plant species have to adapt to these harsh environmental conditions of extremely high temperatures and low precipitation. In this study, gas exchange and water potentials of the Arabian almond tree Amygdalus arabica Olivier (C3-photosynthesis) and four-winged saltbush Atriplex canescens (Pursh) Nutt. (C4-photosynthesis), two drought-tolerant woody species planted previously in an effort to reduce desertification at Karapınar, Konya, and Central Anatolian Region, were periodically measured from May until September under field conditions. Net photosynthesis and transpiration rates, mid-day water potential and water use efficiency were determined throughout the vegetation period in 2015. Maximum net photosynthetic rates were 12.4 μmol m–2 s–1 in the Arabian almond tree and 29.7 μmol m–2 s–1 in four-winged saltbush, measured in July and September, respectively. Also, the highest transpiration rates were 4.8 mmol m–2 s–1 in the Arabian almond tree and 7.1 mmol m–2 s–1 in four-winged saltbush. Maximum water use efficiency values were measured in June in both species, which made up 5.7 and 7.7 mmol CO2 mol–1 H2O for the Arabian almond tree and four-winged saltbush, respectively. Lowest midday water potentials for both species were recorded in August. The results indicate that both species have the ability to tolerate drought stress in the region, though due to its C4 nature of photosynthesis, the four-winged saltbush might overcome those stresses more efficiently than the Arabian almond tree in arid and barren areas
Risk based facility location by using fault tree analysis in disaster management
Determining the locations of facilities for prepositioning supplies to be used during a disaster is a strategic decision that directly affects the success of disaster response operations. Locating such facilities close to the disaster-prone areas is of utmost importance to minimize response time. However, this is also risky because the facility may be disrupted and hence may not support the demand point(s). In this study, we develop an optimization model that minimizes the risk that a demand point may be exposed to because it is not supported by the located facilities. The purpose is to choose the locations such that a reliable facility network to support the demand points is constructed. The risk for a demand point is calculated as the multiplication of the (probability of the) threat (e.g., earthquake), the vulnerability of the demand point (the probability that it is not supported by the facilities), and consequence (value or possible loss at the demand point due to threat). The vulnerability of a demand point is computed by using fault tree analysis and incorporated into the optimization model innovatively. To our knowledge, this paper is the first to use such an approach. The resulting non-linear integer program is linearized and solved as a linear integer program. The locations produced by the proposed model are compared to those produced by the p-center model with respect to risk value, coverage distance, and covered population by using several test problems. The model is also applied in a real problem. The results indicate that taking the risk into account explicitly may create significant differences in the risk levels. © 2014 Elsevier Ltd
Tkachenko waves, glitches and precession in neutron star
Here I discuss possible relations between free precession of neutron stars,
Tkachenko waves inside them and glitches. I note that the proposed precession
period of the isolated neutron star RX J0720.4-3125 (Haberl et al. 2006) is
consistent with the period of Tkachenko waves for the spin period 8.4s. Based
on a possible observation of a glitch in RX J0720.4-3125 (van Kerkwijk et al.
2007), I propose a simple model, in which long period precession is powered by
Tkachenko waves generated by a glitch. The period of free precession,
determined by a NS oblateness, should be equal to the standing Tkachenko wave
period for effective energy transfer from the standing wave to the precession
motion. A similar scenario can be applicable also in the case of the PSR
B1828-11.Comment: 6 pages, no figures, accepted to Ap&S
Lattice dynamics and structural stability of ordered Fe3Ni, Fe3Pd and Fe3Pt alloys
We investigate the binding surface along the Bain path and phonon dispersion
relations for the cubic phase of the ferromagnetic binary alloys Fe3X (X = Ni,
Pd, Pt) for L12 and DO22 ordered phases from first principles by means of
density functional theory. The phonon dispersion relations exhibit a softening
of the transverse acoustic mode at the M-point in the L12-phase in accordance
with experiments for ordered Fe3Pt. This instability can be associated with a
rotational movement of the Fe-atoms around the Ni-group element in the
neighboring layers and is accompanied by an extensive reconstruction of the
Fermi surface. In addition, we find an incomplete softening in [111] direction
which is strongest for Fe3 Ni. We conclude that besides the valence electron
density also the specific Fe-content and the masses of the alloying partners
should be considered as parameters for the design of Fe-based functional
magnetic materials.Comment: Revised version, accepted for publication in Physical Review
Targeting lyn kinase in chorea-acanthocytosis: A translational treatment approach in a rare disease
Background: Chorea-acanthocytosis (ChAc) is a neurodegenerative disease caused by mutations in the VPS13A gene. It is characterized by several neurological symptoms and the appearance of acanthocytes. Elevated tyrosine kinase Lyn activity has been recently identified as one of the key pathophysiological mechanisms in this disease, and therefore represents a promising drug target. Methods: We evaluated an individual off-label treatment with the tyrosine kinase inhibitor dasatinib (100 mg/d, 25.8–50.4 weeks) of three ChAc patients. Alongside thorough safety monitoring, we assessed motor and non-motor scales (e.g., MDS-UPDRS, UHDRS, quality of life) as well as routine and experimental laboratory parameters (e.g., serum neurofilament, Lyn kinase activity, actin cytoskeleton in red blood cells). Results: Dasatinib appeared to be reasonably safe. The clinical parameters remained stable without significant improvement or deterioration. Regain of deep tendon reflexes was observed in one patient. Creatine kinase, serum neurofilament levels, and acanthocyte count did not reveal consistent effects. However, a reduction of initially elevated Lyn kinase activity and accumulated autophagy markers, as well as a partial restoration of the actin cytoskeleton, was found in red blood cells. Conclusions: We report on the first treatment approach with disease-modifying intention in ChAc. The experimental parameters indicate target engagement in red blood cells, while clinical effects on the central nervous system could not be proven within a rather short treatment time. Limited knowledge on the natural history of ChAc and the lack of appropriate biomarkers remain major barriers for “clinical trial readiness”. We suggest a panel of outcome parameters for future clinical trials in ChA
The Magnificent Seven: Magnetic fields and surface temperature distributions
Presently seven nearby radio-quiet isolated neutron stars discovered in ROSAT
data and characterized by thermal X-ray spectra are known. They exhibit very
similar properties and despite intensive searches their number remained
constant since 2001 which led to their name ``The Magnificent Seven''. Five of
the stars exhibit pulsations in their X-ray flux with periods in the range of
3.4 s to 11.4 s. XMM-Newton observations revealed broad absorption lines in the
X-ray spectra which are interpreted as cyclotron resonance absorption lines by
protons or heavy ions and / or atomic transitions shifted to X-ray energies by
strong magnetic fields of the order of 10^13 G. New XMM-Newton observations
indicate more complex X-ray spectra with multiple absorption lines. Pulse-phase
spectroscopy of the best studied pulsars RX J0720.4-3125 and RBS 1223 reveals
variations in derived emission temperature and absorption line depth with pulse
phase. Moreover, RX J0720.4-3125 shows long-term spectral changes which are
interpreted as due to free precession of the neutron star. Modeling of the
pulse profiles of RX J0720.4-3125 and RBS 1223 provides information about the
surface temperature distribution of the neutron stars indicating hot polar caps
which have different temperatures, different sizes and are probably not located
in antipodal positions.Comment: 10 pages, 8 figures, to appear in Astrophysics and Space Science, in
the proceedings of "Isolated Neutron Stars: from the Interior to the
Surface", edited by D. Page, R. Turolla and S. Zan
CP and related phenomena in the context of Stellar Evolution
We review the interaction in intermediate and high mass stars between their
evolution and magnetic and chemical properties. We describe the theory of
Ap-star `fossil' fields, before touching on the expected secular diffusive
processes which give rise to evolution of the field. We then present recent
results from a spectropolarimetric survey of Herbig Ae/Be stars, showing that
magnetic fields of the kind seen on the main-sequence already exist during the
pre-main sequence phase, in agreement with fossil field theory, and that the
origin of the slow rotation of Ap/Bp stars also lies early in the pre-main
sequence evolution; we also present results confirming a lack of stars with
fields below a few hundred gauss. We then seek which macroscopic motions
compete with atomic diffusion in determining the surface abundances of AmFm
stars. While turbulent transport and mass loss, in competition with atomic
diffusion, are both able to explain observed surface abundances, the interior
abundance distribution is different enough to potentially lead to a test using
asterosismology. Finally we review progress on the turbulence-driving and
mixing processes in stellar radiative zones.Comment: Proceedings of IAU GA in Rio, JD4 on Ap stars; 10 pages, 7 figure
Strongly magnetized pulsars: explosive events and evolution
Well before the radio discovery of pulsars offered the first observational
confirmation for their existence (Hewish et al., 1968), it had been suggested
that neutron stars might be endowed with very strong magnetic fields of
-G (Hoyle et al., 1964; Pacini, 1967). It is because of their
magnetic fields that these otherwise small ed inert, cooling dead stars emit
radio pulses and shine in various part of the electromagnetic spectrum. But the
presence of a strong magnetic field has more subtle and sometimes dramatic
consequences: In the last decades of observations indeed, evidence mounted that
it is likely the magnetic field that makes of an isolated neutron star what it
is among the different observational manifestations in which they come. The
contribution of the magnetic field to the energy budget of the neutron star can
be comparable or even exceed the available kinetic energy. The most magnetised
neutron stars in particular, the magnetars, exhibit an amazing assortment of
explosive events, underlining the importance of their magnetic field in their
lives. In this chapter we review the recent observational and theoretical
achievements, which not only confirmed the importance of the magnetic field in
the evolution of neutron stars, but also provide a promising unification scheme
for the different observational manifestations in which they appear. We focus
on the role of their magnetic field as an energy source behind their persistent
emission, but also its critical role in explosive events.Comment: Review commissioned for publication in the White Book of
"NewCompStar" European COST Action MP1304, 43 pages, 8 figure
Synovial hemangioma of the knee joint in a 12-year-old boy: a case report
<p>Abstract</p> <p>Introduction</p> <p>Synovial hemangioma is a rare condition and is frequently misdiagnosed, leading to a diagnostic delay of many years.</p> <p>Case presentation</p> <p>We present a case of an atypical synovial hemangioma in a 12-year-old Caucasian boy with a diagnostic delay of 3 years.</p> <p>Conclusion</p> <p>It is important to know that synovial hemangioma mostly affects the knee joint, showing recurrent bloody effusions without a history of trauma. If there are no intermittent effusions, the diagnosis will be even more difficult. In cases of nonspecific symptoms and longstanding knee pain the diagnosis of a synovial hemangioma should also be considered in order to avoid diagnostic delay. Magnetic resonance imaging is the main diagnostic tool to evaluate patients with synovial hemangioma, showing characteristic lace-like or linear patterns.</p> <p>Angiography can identify feeder vessels and offers the possibility of embolisation in the same setting. Surgical excision, either done per arthroscopy or per arthrotomy, is recommended as soon as possible to avoid the risk of damage to the cartilage.</p
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