Analysis of Some Structuring Principles in Administrative Offenses Law

Historically, the Administrative Offenses Law has its genesis and development in Germany, whose evolution took place after the Second World War, with the German legal and penal system influencing the construction of the current model of Portuguese administrative law. In Portugal, Decree-Law No. 232/1979 introduces into the legal system the regime of administrative offenses, but Decree-Law No. 433/82, of October 27, which through its art. 96 revoked Decree-Law No. 232/1979 and introduced the General Regime of Administrative Offenses (RGCO) and its process in a stable manner. The right of mere ordination is criminal law in a broad sense, so that it justifies the subsidiary application of Criminal Law in cases not covered by the General Regime of Administrative Offenses (RGCO), if the penal rules do not contradict the principles contained in the administrative offenses. Taking into account the structuring principles of the Administrative Offenses Law, the research seeks to analyze some constitutional principles structuring of Criminal Law that are also common to the Administrative Offenses Law, such as the principles of proportionality, guilt and legality. As a result, research has shown that such principles have greater flexibility in the application of this right because the deprivation of people’s freedom is not at stake in Administrative Offense Law intervention

Encrypted antimicrobial peptides from plant proteins.

Abstract Examples of bioactive peptides derived from internal sequences of proteins are known for decades. The great majority of these findings appear to be fortuitous rather than the result of a deliberate and methodological-based enterprise. In the present work, we describe the identification and the biological activities of novel antimicrobial peptides unveiled as internal fragments of various plant proteins founded on our hypothesis-driven search strategy. All putative encrypted antimicrobial peptides were selected based upon their physicochemical properties that were iteratively selected by an in-house computer program named Kamal. The selected peptides were chemically synthesized and evaluated for their interaction with model membranes. Sixteen of these peptides showed antimicrobial activity against human and/or plant pathogens, some with a wide spectrum of activity presenting similar or superior inhibition efficacy when compared to classical antimicrobial peptides (AMPs). These original and previously unforeseen molecules constitute a broader and undisputable set of evidences produced by our group that illustrate how the intragenic concept is a workable reality and should be carefully explored not only for microbicidal agents but also for many other biological functions

Utilização do diagnóstico de enfermagem segundo a classificação da NANDA, para a sistematização da assistência de enfermagem em aleitamento materno

The present study aimed at describing the reformulated instrument used in the puerperal woman nursing consultation based on the identified diagnoses classification according to the Taxonomy-I reviewed by NANDA, and the identification of the most frequent nursing diagnoses concerning maternal breastfeeding, based on the reformulated instrument. The diagnoses found as being over 50% were: knowledge deficit (100%); sleep pattern disturbance (75%), altered sexuality patterns (75%), ineffective breastfeeding (66,6%) and impaired physical mobility (66,6%).En este estudio se describe el proceso de reformulación de un guía de evaluación de puérperas, utilizado en la consulta de enfermeria, teniendo como referencia la clasificación de los diagnósticos de enfermería de la Taxonomía I-revisada por la Asociación Norteamericana de Enfermería (NANDA). También son determinados los diagnósticos de enfermería relacionados con la lactancia materna, que fueron calificados con porcentajes superiores a 50%, a partir de la aplicación de la guía reformulada. Ellos son: déficit de conocimiento (100,0%), cambios en el patrón del sueño (75,0%), cambios en el patrón de sexualidad (75,0%), lactancia ineficaz (66,6%) y movilidad física disminuida.Este estudo teve por objetivos descrever a reformulação de um instrumento utilizado na consulta de enfermagem à puérpera, com base na classificação dos diagnósticos de enfermagem, segundo a Taxonomia I-revisada da American Nursing Diagnosis Association - NANDA, e identificar os diagnósticos de enfermagem mais frequentes, relacionados ao aleitamento materno a partir da utilização deste instrumento. Os diagnósticos encontrados em percentuais acima de 50% foram: déficit de conhecimento (100,0%); distúrbio no padrão do sono (75,0%); alteração no padrão de sexualidade (75,0%); amamentação ineficaz (66,6%) e mobilidade física prejudicada (66,6%)

Utilização do diagnóstico de enfermagem segundo a classificação da NANDA, para a sistematização da assistência de enfermagem em aleitamento materno

The present study aimed at describing the reformulated instrument used in the puerperal woman nursing consultation based on the identified diagnoses classification according to the Taxonomy-I reviewed by NANDA, and the identification of the most frequent nursing diagnoses concerning maternal breastfeeding, based on the reformulated instrument. The diagnoses found as being over 50% were: knowledge deficit (100%); sleep pattern disturbance (75%), altered sexuality patterns (75%), ineffective breastfeeding (66,6%) and impaired physical mobility (66,6%).En este estudio se describe el proceso de reformulación de un guía de evaluación de puérperas, utilizado en la consulta de enfermeria, teniendo como referencia la clasificación de los diagnósticos de enfermería de la Taxonomía I-revisada por la Asociación Norteamericana de Enfermería (NANDA). También son determinados los diagnósticos de enfermería relacionados con la lactancia materna, que fueron calificados con porcentajes superiores a 50%, a partir de la aplicación de la guía reformulada. Ellos son: déficit de conocimiento (100,0%), cambios en el patrón del sueño (75,0%), cambios en el patrón de sexualidad (75,0%), lactancia ineficaz (66,6%) y movilidad física disminuida.Este estudo teve por objetivos descrever a reformulação de um instrumento utilizado na consulta de enfermagem à puérpera, com base na classificação dos diagnósticos de enfermagem, segundo a Taxonomia I-revisada da American Nursing Diagnosis Association - NANDA, e identificar os diagnósticos de enfermagem mais frequentes, relacionados ao aleitamento materno a partir da utilização deste instrumento. Os diagnósticos encontrados em percentuais acima de 50% foram: déficit de conhecimento (100,0%); distúrbio no padrão do sono (75,0%); alteração no padrão de sexualidade (75,0%); amamentação ineficaz (66,6%) e mobilidade física prejudicada (66,6%)

Sudden unexpected death in an adolescent with epilepsy: All roads lead to the heart?

The incidence of sudden unexpected death in epilepsy (SUDEP) has been estimated from 0.5-1.4/1,000 person-years in people with treated epilepsy, and 9/1,000 person-years in candidates for epilepsy surgery. Potential risk factors for SUDEP include: age, early onset of epilepsy, duration of epilepsy, uncontrolled seizures, seizure type and winter temperatures. The arrythmogenic side-effect of antiepileptic drugs and seizures may increase the risk of SUDEP. In this report, we describe a patient with prolonged post-ictal tachycardia in EEG video recordings with a typical case of SUDEP: a 16-year-old boy with medically intractable complex partial seizures. Magnetic resonance imaging revealed left mesial temporal sclerosis. During non-invasive video-EEG monitoring, the patient presented a post-ictal heart rate increased for five hours. Two months after video-EEG, he died from SUDEP during a tonic-clonic secondary generalized seizure. The possibility of cardiac involvement in the pathogenesis of SUDEP has been suggested by many studies. Evaluation of this patient with EEG-video monitoring, including measurement of heart rate, contributed to an identification of ictal tachycardia that may have played a role in the SUDEP. Premature mortality seems to be increased in patients with epilepsy, and cardiac abnormalities may be a possible cause of SUDEP. (Cardiol J 2011; 18, 2: 194-196)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)INCT/MCTConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Univ Sao Paulo, Ctr Cirurgia Epilepsia, Dept Neurociencias & Ciencias Comportamento, Fac Med Ribeirao Preto,Ctr Cirurgia Epilepsia CIR, BR-14048900 Sao Paulo, BrazilUniv Fed Sao Paulo, Disciplina Neurol Expt, Escola Paulista Med UNIFESP EPM, Sao Paulo, BrazilUniv Fed Sao Paulo, Dept Fisiol, Escola Paulista Med UNIFESP EPM, Sao Paulo, BrazilUniv Fed Sao Paulo, Disciplina Neurol Expt, Escola Paulista Med UNIFESP EPM, Sao Paulo, BrazilUniv Fed Sao Paulo, Dept Fisiol, Escola Paulista Med UNIFESP EPM, Sao Paulo, BrazilWeb of Scienc