Falling birth rates and world population decline: A quantitative discussion (1950-2040)

The UN data (1950-2010) and projections (both medium and low-fertility variants for 2015- 2040) show that fertility rates are already below replacement level in all continents except Africa. In this paper we develop a simple new approach for population projections based on a Improved Rate Equations (IRE) model. Population projections under the (1) Malthusian assumption, (2) an (IRE) model fitting and extrapolating from actual UN population data up to 2040, and (3) UN projections (low-fertility variant), are compared. The model fits quite well actual data and suggests a world population decline in the 21st Century. The economic, social and political consequences of this new and global circumstance would be far reachin

Lepton masses, mixings and FCNC in a minimal S_3-invariant extension of the Standard Model

The mass matrices of the charged leptons and neutrinos, previously derived in a minimal S_3-invariant extension of the Standard Model, were reparametrized in terms of their eigenvalues. We obtained explicit, analytical expressions for all entries in the neutrino mixing matrix, V_PMNS, the neutrino mixing angles and the Majorana phases as functions of the masses of charged leptons and neutrinos in excellent agreement with the latest experimental values. The resulting V_PMNS matrix is very close to the tri-bimaximal form of the neutrino mixing matrix. We also derived explicit analytical expressions for the matrices of the Yukawa couplings and computed the branching ratios of some selected flavour changing neutral current processes as functions of the masses of the charged leptons and the neutral Higgs bosons. We find that the S_3 x Z_2 flavour symmetry and the strong mass hierarchy of the charged leptons strongly suppress the FCNC processes in the leptonic sector well below the present experimental upper bounds by many orders of magnitude.Comment: One paragraph added with comparison to tri-bimaximal mixing, two lines changed in abstract, references added, typographical errors correcte

Influence of M-phase chromatin on the anisotropy of microtubule asters

In many eukaryotic cells going through M-phase, a bipolar spindle is formed by microtubules nucleated from centrosomes. These microtubules, in addition to being "captured" by kinetochores, may be stabilized by chromatin in two different ways: short-range stabilization effects may affect microtubules in close contact with the chromatin, while long-range stabilization effects may "guide" microtubule growth towards the chromatin (e.g., by introducing a diffusive gradient of an enzymatic activity that affects microtubule assembly). Here, we use both meiotic and mitotic extracts from Xenopus laevis eggs to study microtubule aster formation and microtubule dynamics in the presence of chromatin. In "low-speed" meiotic extracts, in the presence of salmon sperm chromatin, we find that short-range stabilization effects lead to a strong anisotropy of the microtubule asters. Analysis of the dynamic parameters of microtubule growth show that this anisotropy arises from a decrease in the catastrophe frequency, an increase in the rescue frequency and a decrease in the growth velocity. In this system we also find evidence for long-range "guidance" effects, which lead to a weak anisotropy of the asters. Statistically relevant results on these long-range effects are obtained in "high-speed" mitotic extracts in the presence of artificially constructed chromatin stripes. We find that aster anisotropy is biased in the direction of the chromatin and that the catastrophe frequency is reduced in its vicinity. In this system we also find a surprising dependence of the catastrophe and the rescue frequencies on the length of microtubules nucleated from centrosomes: the catastrophe frequency increase and the rescue frequency decreases with microtubule length

On the Rational Type 0f Moment Angle Complexes

In this note it is shown that the moment angle complexes Z(K;(D^2,,S^1)) which are rationally elliptic are a product of odd spheres and a diskComment: This version avoids the use of an incorrect result from the literature in the proof of Theorem 1.3. There is some text overlap with arXiv:1410.645