Cosmiatry: An analysis of the Brazilian market

Introduction: The aesthetic procedure market is growing exponentially in Brazil. This growth has aroused the interest of several professional categories. The decision to practice in the sector must consider the market opportunities in the location in which you intend to operate. However, the area lacks comparative analyses documenting probable regional differences in the country. The objective of the study is to describe market differences in aesthetic procedures between Brazilian states and regions. An index of potential cosmetic consumption (IPCC) is calculated for such a comparative analysis. Method: Cross-sectional study involving providers of nonsurgical aesthetic procedures in Brazil. Searches on Google Maps® were conducted using key terms, and telephone interviews were conducted to obtain information on professional categories, types of providers, and services offered. Positive predictive values were obtained for all search strategies and used to estimate the total number of providers. Population size and per capita income were considered to calculate the IPCCs for Brazilian states. Results: São Paulo, Minas Gerais, and Rio de Janeiro presented the highest IPCCs, being 524, 210, and 180, respectively. Roraima had an IPCC of 14, the lowest in the country. The Southeast Region presented, on average, the highest IPCC (242) among all Brazilian regions. Conclusion: Considering population size and income, the Southeast Region presents the greatest market opportunities for nonsurgical aesthetic procedures in Brazil. Our findings may be of interest to healthcare professionals and investors who work or intend to work in the sector

Polymorphisms of the TP53 codon 72 and WRN codon 1367 in individuals from Northern Brazil with gastric adenocarcinoma

Gastric cancer is the second most frequent type of neoplasia and also the second most common cause of death in the world. TP53 codon 72, which produces variant proteins with an arginine (Arg) or proline (Pro), has been reported to be associated with cancers of the lung, oesophagus, stomach and cervix. Werner's syndrome (WS) is a premature ageing disease caused by a mutation in the WRN gene. the WRN protein acts as a DNA helicase and as an exonuclease. WRN codon 1367 produces variant proteins with an Arg or cysteine (Cys). This polymorphism has been studied, in order to understand the clinical impact of the molecular variants in WS and in age-related disorders. in the present study, the TP53 codon 72 and the WRN codon 1367 polymorphisms were investigated in 54 gastric adenocarcinoma patients (31 diffuse-type and 25 intestinal-type) and 54 controls. DNA samples were extracted, and PCR-RFLP was utilised for genotyping TP53 codon 72 and WRN codon 1367. the allele frequencies of the TP53 polymorphism were: Arg=0.74 and Pro=0.26. the allele frequencies of the WRN polymorphism were: Cys=0.73 and Arg=0.27. the crude genotypic frequencies in gastric cancer patients were similar to those of the controls, but in the WRN codon 1367 polymorphisms the mean age tended to be higher in the Arg/Arg genotypes. There also was an association, although not statistically significant, between the presence of Helicobacter pylori and the genotypes Cys/Cys and Cys/Arg and a higher percentage of cardia cancer among the Arg/Arg genotypes, and of non-cardia cancer among genotypes Cys/Cys and Cys/Arg. These findings may be a reflection of differences in the interaction between WRN codon 1367 polymorphisms and local factors in the stomach. To our knowledge, this is the first study to examine a genetic polymorphism of the WRN gene in cancer. the precise mechanisms of action of the TP53 and WRN polymorphisms involved in the aetiopathogeny of this disease need further investigation.Fed Univ Para, Ctr Ciencias Biol, Dept Biol, Lab Citogenet Humana, BR-66075900 Belem, Para, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Disciplina Genet, São Paulo, BrazilFac Med Marilia, Disciplinas Genet & Biol Mol, Marilia, SP, BrazilUniv São Paulo, Fac Med Ribeirao Preto, Dept Genet, Ribeirao Preto, SP, BrazilHosp Univ Joao de Barros Barreto, Serv Cirurgia, UFPA, Belem, Para, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Disciplina Genet, São Paulo, BrazilWeb of Scienc

O Museu do Estado da Bahia, entre ideais e realidades (1918 a 1959)

This article retraces the trajectory of the Museu do Estado da Bahia from 1918 to 1959. The aim is to identify its successive museological practices and the implementation of the so-called processes of musealization during its institutionalization and consolidation, which were also related to the personalities of the administrators and their expectations regarding political and social interactions, as well their expectations toward the State of Bahia itself. Having dealt with a wide range of conflicts, alterations have been observed in how the museum functions. Within the framework in question, three successive periods have been characterized: its establishment as a historic museum; its consolidation as an eclectic museum with a focus on history, and the path towards art under the direction of José Valladares

Resumos concluídos - Saúde Coletiva

Resumos concluídos - Saúde Coletiv