О целесообразности применения определителя Гурвица для проверки устойчивости систем автоматического управления

Указываются отличия между критерием устойчивости Гурвица и критерием Рауса и обосновываются существенные преимущества последнего по условиям достоверности результатов и трудоемкости для исследователя.The differences between the Hurwitz stability criterion and the Routh criterion are shown in the paper and the essential advantage of the latter in terms of reliability and laboriousness is grounded

Clozapine-induced reversible Brugada Syndrome

We describe a case of reversible Brugada Syndrome in a patient on Clozapine for schizophrenia, highlighting the risk of antipsychotics causing a variety of phenotypic expressions of predisposing sodium channelopathy

Исследования микроструктуры, состава и свойств конструкционного чугуна, применяемого для изготовления корпусных отливок автомобилестроения

В статье описаны результаты исследований микроструктуры, химического состава и свойств чугуна промышленных плавок. Результаты данных исследований позволяют выявить фактический химический состав базового чугуна для разработки дальнейших технологических процессов модифицирования чугуна недефицитными эффективными модификаторами

Профессору О. П. Муравлеву - 70 лет

9 октября исполнилось 70 лет со дня рождения профессора Томского политехнического университета Олега Павловича Муравлева

Symmetries and Symmetry Breaking

In understanding the world of matter, the introduction of symmetry principles following experimentation or using the predictive power of symmetry principles to guide experimentation is most profound. The conservation of energy, linear momentum, angular momentum, charge, and CPT involve fundamental symmetries. All other conservation laws are valid within a restricted subspace of the four interactions: the strong, the electromagnetic, the weak, and the gravitational interaction. In this paper comments are made regarding parity violation in hadronic systems, charge symmetry breaking in two nucleon and few nucleon systems, and time-reversal-invariance in hadronic systems.Comment: 5 Pages, LaTeX, 2 PostScript figures. Talk at 17th International IUPAP Conference on Few-body Problems in Physics, June 5-10, 2003, Durham, North Carolina, US

Синтез мультитопных лигандов -производных имидазола и триазола с использованием фениленового линкера

Aufgrund veränderter Marktbedingungen sind produzierende Unternehmen zunehmend gezwungen, sich mit immer komplexeren Produkten und steigender Variantenvielfalt in kürzeren Zeitabschnitten auf wettbewerbsintensiven Märkten zu behaupten. Als Konsequenz ist es erforderlich, die Produktentwicklung effektiver und effizienter zu gestalten. Demzufolge müssen auch die mit Werkstoff- und Verfahrensinnovationen verbundenen Rationalisierungspotentialen gezielt genutzt werden. Dies ist jedoch nur möglich, wenn werkstoff- und verfahrensspezifische Restriktionen bereits in einer frühen Produktentwicklungsphase Berücksichtigung finden. Um hierfür geeignete Voraussetzungen zu schaffen, wurden EDV-Hilfsmittel entwickelt. Die Prototypen Innotech, Ratech und Techbase unterstützen die integrierte Technologieplanung und ermöglichen bereits in frühen Phasen der Produktentwicklung eine optimale Abstimmung der Faktoren Gestalt, Werkstoff und Technologie

Care reality of menopausal women in Germany: healthcare research using quantitative (SHI claims data) and qualitative (survey) data collection.

PURPOSE The transition from the fertile phase of life to menopause is associated with numerous physical changes. Hormone replacement therapy (HRT), as the most effective and efficient form of drug treatment, involves the use of oestrogens and progestins with the aim of increasing health-related quality of life through symptom reduction, sleep improvement and affect enhancement. METHODS The medical care situation and disease burden of menopausal women was investigated by means of a survey of 1000 women aged 45-60 years on the topics of quality of life, menopause and HRT and a quantitative, longitudinal healthcare study based on an anonymised and age- and sex-adjusted Statutory Health Insurance (SHI) routine data set with approximately four million anonymous insured persons per year. RESULTS Out of more than half a million women aged 35-70 years, and with statutory health insurance, (n = 613,104), 14% (n = 82,785) had climacteric disorder documented as a first diagnosis in 2014. The proportion of women with the climacteric disorder, who were prescribed HRT on an outpatient basis, was 21%; according to the forsa survey, 50% of the women surveyed felt moderate to poorly/very poorly informed about treatment options. CONCLUSION Findings from the health insurance research conducted with different data sources (survey and SHI claims data) indicate the need for increasing awareness and providing an early and informative education on HRT and its risks and benefits