Spatial variabilities and their relationships of the trends of temperature, water vapor, and precipitation in the North American Regional Reanalysis

[1] Spatial variabilities and their relationships of the trends of temperature, water vapor, and precipitation in the North American Regional Reanalysis are examined for each season from March 1979 to February 2007. Results show that warming dominates the domain in the troposphere from the surface to 300 hPa. Water vapor increases at lower levels but does not change much at mid-upper levels. Because of the large increase of water vapor holding capacity of the air at all levels due to the warming, relative humidity has a decreasing trend at all levels. The decrease is small at the surface and largest at midlevels. Precipitation, which corresponds well to ascending motion in trends, both increases and decreases in about half of the domain. Statistical analysis from the very large spatial samples indicates that the precipitation trend positively relates to both specific humidity trend and relative humidity trend. However, temperature trend positively relates to specific humidity trend but negatively relates to relative humidity trend. So, in strong warming places, whether precipitation increases or not depends on whether the decrease of relative humidity becomes a limiting factor; small decrease of relative humidity may still allow precipitation to increase, but large decrease of relative humidity may make precipitation decrease. The uncertain relationship between the trends of precipitation and temperature can also be understood from the nonlinear characteristics of the atmospheric processes

The Relationships between Climatic and Hydrological Changes in the Upper Mississippi River Basin: A SWAT and Multi-GCM Study

Changes in major climatic and hydrological quantities in the upper Mississippi River basin and their interrelationships are studied with the Soil and Water Assessment Tool being driven by the contemporary climate and future scenario simulations of 10 global models in the Intergovernmental Panel on Climate Change (IPCC) Data Archive. Although the seasonal cycles of climate and hydrological quantities simulated by the 10 models have differences, the ensemble is very close to the observation. Ensemble predictions show that with warming in all months, precipitation decreases in summer but increases in all other seasons. Correspondingly, streamflow decreases in all seasons except winter, evapotranspiration decreases in July–September and increases in all other months, and snowmelt increases in winter but decreases in spring and fall. To understand the linkages between the cross-century changes of climate and hydrological quantities and the relative importance of the changes of temperature and precipitation to the changes of hydrological quantities, relationships between interannual variations of these quantities are investigated. It is shown that the change rates of the hydrological quantities with respect to temperature and precipitation obtained from regressions of interannual variations can vary greatly from month to month; however, on a monthly basis, they do not change much from the current to the future periods. Evaluations with these change rates indicate that for interannual variations of hydrological quantities, both variations of temperature and precipitation are important, and their relative importance depends on the month of the year. However, the changes of hydrological quantities from the means of the current years to the means of the future are dominated by warming in all months, and the influence from change of precipitation is much smaller. The changes of the hydrological quantities can be well predicted with the change rates from the warming alone

Pd/CeO2/SiC Chemical Sensors

The incorporation of nanostructured interfacial layers of CeO2 has been proposed to enhance the performances of Pd/SiC Schottky diodes used to sense hydrogen and hydrocarbons at high temperatures. If successful, this development could prove beneficial in numerous applications in which there are requirements to sense hydrogen and hydrocarbons at high temperatures: examples include monitoring of exhaust gases from engines and detecting fires. Sensitivity and thermal stability are major considerations affecting the development of high-temperature chemical sensors. In the case of a metal/SiC Schottky diode for a number of metals, the SiC becomes more chemically active in the presence of the thin metal film on the SiC surface at high temperature. This increase in chemical reactivity causes changes in chemical composition and structure of the metal/SiC interface. The practical effect of the changes is to alter the electronic and other properties of the device in such a manner as to degrade its performance as a chemical sensor. To delay or prevent these changes, it is necessary to limit operation to a temperature <450 C for these sensor structures. The present proposal to incorporate interfacial CeO2 films is based partly on the observation that nanostructured materials in general have potentially useful electrical properties, including an ability to enhance the transfer of electrons. In particular, nanostructured CeO2, that is CeO2 with nanosized grains, has shown promise for incorporation into hightemperature electronic devices. Nanostructured CeO2 films can be formed on SiC and have been shown to exhibit high thermal stability on SiC, characterized by the ability to withstand temperatures somewhat greater than 700 C for limited times. The exchanges of oxygen between CeO2 and SiC prevent the formation of carbon and other chemical species that are unfavorable for operation of a SiC-based Schottky diode as a chemical sensor. Consequently, it is anticipated that in a Pd/CeO2/SiC Schottky diode, the nanostructured interfacial CeO2 layer would contribute to thermal stability and, by contributing to transfer of electrons, would also contribute to sensitivity

Gas-Phase Synthesis of Triphenylene (C18 H12 ).

For the last decades, the hydrogen-abstraction-acetylene-addition (HACA) mechanism has been widely invoked to rationalize the high-temperature synthesis of PAHs as detected in carbonaceous meteorites (CM) and proposed to exist in the interstellar medium (ISM). By unravelling the chemistry of the 9-phenanthrenyl radical ([C14 H9 ]. ) with vinylacetylene (C4 H4 ), we present the first compelling evidence of a barrier-less pathway leading to a prototype tetracyclic PAH - triphenylene (C18 H12 ) - via an unconventional hydrogen abstraction-vinylacetylene addition (HAVA) mechanism operational at temperatures as low as 10 K. The barrier-less, exoergic nature of the reaction reveals HAVA as a versatile reaction mechanism that may drive molecular mass growth processes to PAHs and even two-dimensional, graphene-type nanostructures in cold environments in deep space thus leading to a better understanding of the carbon chemistry in our universe through the untangling of elementary reactions on the most fundamental level

Transcriptional Modulation of Intestinal Innate Defense/Inflammation Genes by Preterm Infant Microbiota in a Humanized Gnotobiotic Mouse Model

Background and Aims: It is known that postnatal functional maturation of the small intestine is facilitated by microbial colonization of the gut. Preterm infants exhibit defects in gut maturation, weak innate immunity against intestinal infection and increased susceptibility to inflammatory disorders, all of which may be related to the inappropriate microbial colonization of their immature intestines. The earliest microbes to colonize the preterm infant gut encounter a naïve, immature intestine. Thus this earliest microbiota potentially has the greatest opportunity to fundamentally influence intestinal development and immune function. The aim of this study was to characterize the effect of early microbial colonization on global gene expression in the distal small intestine during postnatal gut development.Methods: Gnotobiotic mouse models with experimental colonization by early (prior to two weeks of life) intestinal microbiota from preterm human infants were utilized. Microarray analysis was used to assess global gene expression in the intestinal epithelium.Results and Conclusion: Multiple intestinal genes involved in metabolism, cell cycle regulation, cell-cell or cell-extracellular matrix communication, and immune function are developmental- and intestinal microbiota- regulated. Using a humanized gnotobiotic mouse model, we demonstrate that certain early preterm infant microbiota from prior to 2 weeks of life specifically induce increased NF-κB activation and a phenotype of increased inflammation whereas other preterm microbiota specifically induce decreased NF-κB activation. These fundamental differences correlate with altered clinical outcomes and suggest the existence of optimal early microbial communities to improve health outcomes.</p

Regulation of TrkB receptor tyrosine kinase and its internalization by neuronal activity and Ca2+ influx

Internalization of the neurotrophin–Trk receptor complex is critical for many aspects of neurotrophin functions. The mechanisms governing the internalization process are unknown. Here, we report that neuronal activity facilitates the internalization of the receptor for brain-derived neurotrophic factor, TrkB, by potentiating its tyrosine kinase activity. Using three independent approaches, we show that electric stimulation of hippocampal neurons markedly enhances TrkB internalization. Electric stimulation also potentiates TrkB tyrosine kinase activity. The activity-dependent enhancement of TrkB internalization and its tyrosine kinase requires Ca2+ influx through N-methyl-d-aspartate receptors and Ca2+ channels. Inhibition of internalization had no effect on TrkB kinase, but inhibition of TrkB kinase prevents the modulation of TrkB internalization, suggesting a critical role of the tyrosine kinase in the activity-dependent receptor endocytosis. These results demonstrate an activity- and Ca2+-dependent modulation of TrkB tyrosine kinase and its internalization, and they provide new insights into the cell biology of tyrosine kinase receptors

Observation of Floquet Chern insulators of light

The field of topological photonics studies unique and robust photonic systems that are immune to defects and disorders due to the protection of their underlying topological phases. Mostly implemented in static systems, the studied topological phases are often defined in linear photonic band structures. In this study, we experimentally demonstrate Floquet Chern insulators in periodically driven nonlinear photonic crystals, where the topological phase is controlled by the polarization and the frequency of the driving field. Mediated by strong material nonlinearity, our system enters what we call the 'strong Floquet coupling regime', where the photonic Floquet bands cross and open new energy gaps with non-trivial topology as observed in our transient sum-frequency generation measurements. Our work offers new opportunities to explore the role of classical optical nonlinearity in topological phases and their applications in nonlinear optoelectronics.Comment: 24 pages, 5 figure