Post-Hospital Syndrome and Hyponatremia

Introduction: Post-hospital syndrome (PHS) is defined as a period of vulnerability during the first 30 days after a patient is discharged from hospital, in which multiple factors come into play. Hyponatremia is the most frequent hydroelectrolytic disorder in hospitalized patients and may be related to the appearance of PHS. Objective: The objective is to estimate the prevalence of PHS that is assessed as the rate of readmissions in the first 30 days after discharge, in patients with hyponatremia. Material and Methods: It is a descriptive observational study of patients with hyponatremia who were discharged from 1 September 2010 to 2 February 2020 at the Internal Medicine Service of the Hospital University of San Juan (Alicante, Spain). Results: Of the 25 included patients, 5 (20%) were readmitted within a month of discharge, after a mean of 11.4 days (standard deviation [SD] 5.1). The overall mortality of the study was 20% (n = 5), with one case of death in the first 30 days post-hospitalization (4%). In 12 patients (48%) the origin of the hyponatremia was undetermined. The most frequently recorded etiology for the condition was pharmacological (n = 7, 28%), and there was pronounced variability in its clinical and laboratory study. The most widely used corrective measure was drug withdrawal, in 16 patients (64%). Water intake restriction was the most common treatment after discharge (5 patients, 20%), followed by urea (2 patients, 8%), while tolvaptan was not used. Conclusion: Hyponatremia may be the cause of PHS, which could increase the rate of early readmission. Hyponatremia is an underdiagnosed and undertreated entity, so it is necessary to apply an appropriate system to optimize its management and, in future studies, to assess its impact on PHS

Nutritional and Functional Impact of Acute SARS-CoV-2 Infection in Hospitalized Patients

Aim: To assess the prevalence of malnutrition, frailty, and sarcopenia and the relationships between them in patients hospitalized for COVID-19. Methods: This was a cross-sectional study of the prevalence, determinants, and associations between malnutrition (GLIM 2019 criteria), sarcopenia (SARC-F scale, dynamometry, and calf circumference), and frailty (FRAIL scale) upon discharge following hospitalization for COVID 19. Results: A total of 101 patients (67.3% men, mean age 66.3 years) were recruited. Malnutrition was diagnosed in 49.5%, sarcopenia in 32.7%, and frailty in 28.7% of patients. Of the patients with malnutrition, 48% were also sarcopenic, and 42% were frail. There was a significant association between malnutrition and the severity of pneumonia according to the CURB-65 scale (odds ratio [OR] 2.61, p = 0.036), between sarcopenia and a Barthel score lower than 60 points (OR 29.52, p < 0.001), and between frailty and both a Barthel score lower than 60 points (OR 32.27, p < 0.001) and a length of hospital stay of over 30 days (OR 9.11, p = 0.008). Conclusions: Malnutrition, sarcopenia, and frailty are prevalent and interrelated entities in patients hospitalized for acute SARS CoV-2 infection, especially in patients with greater baseline functional impairment prior to admission and a higher infection severity

First measurement of the top quark pair production cross section in proton-proton collisions at s\sqrt{s} = 13.6 TeV

The first measurement of the top quark pair ($\mathrm{t\bar{t}}$) production cross section in proton-proton collisions at $\sqrt{s}$ = 13.6 TeV is presented. Data recorded with the CMS detector at the CERN LHC in Summer 2022, corresponding to an integrated luminosity of 1.21 fb$^{-1}$, are analyzed. Events are selected with one or two charged leptons (electrons or muons) and additional jets. A maximum likelihood fit is performed in event categories defined by the number and flavors of the leptons, the number of jets, and the number of jets identified as originating from b quarks. An inclusive $\mathrm{t\bar{t}}$ production cross section of 882 $\pm$ 23 (stat+syst) $\pm$ 20 (lumi) pb is measured, in agreement with the standard model prediction of 921$^{+29}_{-37}$ pb

Multiplicity and transverse momentum dependence of charge-balance functions in pPb and PbPb collisions at LHC energies

International audienceMeasurements of the charge-dependent two-particle angular correlation function in proton-lead (pPb) collisions at a nucleon-nucleon center-of-mass energy of $\sqrt{s_\mathrm{NN}}$ = 8.16 TeV and lead-lead (PbPb) collisions at$\sqrt{s_\mathrm{NN}}$ = 5.02 TeV are reported. The pPb and PbPb datasets correspond to integrated luminosities of 186\nbinv and 0.607 nb$^{-1}$, respectively, and were collected using the CMS detector at the CERN LHC. The charge-dependent correlations are characterized by balance functions of same- and opposite-sign particle pairs. The balance functions, which contain information about the creation time of charged particle pairs and the development of collectivity, are studied as functions of relative pseudorapidity ($\Delta \eta$) and relative azimuthal angle ($\Delta \phi$), for various multiplicity and transverse momentum ($p_\mathrm{T}$) intervals. A multiplicity dependence of the balance function is observed in $\Delta \eta$ and $\Delta \phi$ for both systems. The width of the balance functions decreases towards high-multiplicity collisions in the momentum region $\lt$2 GeV, for pPb and PbPb results. No multiplicity dependence is observed at higher transverse momentum. The data are compared with HYDJET, HIJING and AMPT generator predictions, none of which capture completely the multiplicity dependence seen in the data

Multiplicity and transverse momentum dependence of charge-balance functions in pPb and PbPb collisions at LHC energies

International audienceMeasurements of the charge-dependent two-particle angular correlation function in proton-lead (pPb) collisions at a nucleon-nucleon center-of-mass energy of $\sqrt{s_\mathrm{NN}}$ = 8.16 TeV and lead-lead (PbPb) collisions at$\sqrt{s_\mathrm{NN}}$ = 5.02 TeV are reported. The pPb and PbPb datasets correspond to integrated luminosities of 186\nbinv and 0.607 nb$^{-1}$, respectively, and were collected using the CMS detector at the CERN LHC. The charge-dependent correlations are characterized by balance functions of same- and opposite-sign particle pairs. The balance functions, which contain information about the creation time of charged particle pairs and the development of collectivity, are studied as functions of relative pseudorapidity ($\Delta \eta$) and relative azimuthal angle ($\Delta \phi$), for various multiplicity and transverse momentum ($p_\mathrm{T}$) intervals. A multiplicity dependence of the balance function is observed in $\Delta \eta$ and $\Delta \phi$ for both systems. The width of the balance functions decreases towards high-multiplicity collisions in the momentum region $\lt$2 GeV, for pPb and PbPb results. No multiplicity dependence is observed at higher transverse momentum. The data are compared with HYDJET, HIJING and AMPT generator predictions, none of which capture completely the multiplicity dependence seen in the data

Probing small Bjorken-xx nuclear gluonic structure via coherent J/ψ\psi photoproduction in ultraperipheral PbPb collisions at sNN\sqrt{s_\mathrm{NN}} = 5.02 TeV

International audienceQuasi-real photons exchanged in relativistic heavy ion interactions are powerful probes of the gluonic structure of nuclei. The first measurement of the coherent J/$\psi$ photoproduction cross section in ultraperipheral lead-lead collisions is presented over a wide range of photon-nucleus center-of-mass energies per nucleon (W$^\text{Pb}_{\gamma\text{N}}$). Results are obtained using data at the nucleon-nucleon center-of-mass energy of 5.02 TeV collected by the CMS experiment at the CERN LHC, corresponding to an integrated luminosity of 1.52 nb$^{-1}$. The cross section is observed to rise rapidly at low W$^\text{Pb}_{\gamma\text{N}}$, and plateau above W$^\text{Pb}_{\gamma\text{N}}$$\approx$ 40 GeV, up to 400 GeV, a new regime of small Bjorken-$x$ ($\approx$ 6 $\times$ 10$^{-5}$) gluons being probed in a heavy nucleus. The observed energy dependence is not predicted by current quantum chromodynamic models

Probing small Bjorken-xx nuclear gluonic structure via coherent J/ψ\psi photoproduction in ultraperipheral PbPb collisions at sNN\sqrt{s_\mathrm{NN}} = 5.02 TeV

International audienceQuasi-real photons exchanged in relativistic heavy ion interactions are powerful probes of the gluonic structure of nuclei. The first measurement of the coherent J/$\psi$ photoproduction cross section in ultraperipheral lead-lead collisions is presented over a wide range of photon-nucleus center-of-mass energies per nucleon (W$^\text{Pb}_{\gamma\text{N}}$). Results are obtained using data at the nucleon-nucleon center-of-mass energy of 5.02 TeV collected by the CMS experiment at the CERN LHC, corresponding to an integrated luminosity of 1.52 nb$^{-1}$. The cross section is observed to rise rapidly at low W$^\text{Pb}_{\gamma\text{N}}$, and plateau above W$^\text{Pb}_{\gamma\text{N}}$$\approx$ 40 GeV, up to 400 GeV, a new regime of small Bjorken-$x$ ($\approx$ 6 $\times$ 10$^{-5}$) gluons being probed in a heavy nucleus. The observed energy dependence is not predicted by current quantum chromodynamic models

Probing small Bjorken-xx nuclear gluonic structure via coherent J/ψ\psi photoproduction in ultraperipheral PbPb collisions at sNN\sqrt{s_\mathrm{NN}} = 5.02 TeV

Quasi-real photons exchanged in relativistic heavy ion interactions are powerful probes of the gluonic structure of nuclei. The first measurement of the coherent J/$\psi$ photoproduction cross section in ultraperipheral lead-lead collisions is presented over a wide range of photon-nucleus center-of-mass energies per nucleon (W$^\text{Pb}_{\gamma\text{N}}$). Results are obtained using data at the nucleon-nucleon center-of-mass energy of 5.02 TeV collected by the CMS experiment at the CERN LHC, corresponding to an integrated luminosity of 1.52 nb$^{-1}$. The cross section is observed to rise rapidly at low W$^\text{Pb}_{\gamma\text{N}}$, and plateau above W$^\text{Pb}_{\gamma\text{N}}$$\approx$ 40 GeV, up to 400 GeV, a new regime of small Bjorken-$x$ ($\approx$ 6 $\times$ 10$^{-5}$) gluons being probed in a heavy nucleus. The observed energy dependence is not predicted by current quantum chromodynamic models

Multiplicity and transverse momentum dependence of charge-balance functions in pPb and PbPb collisions at LHC energies

International audienceMeasurements of the charge-dependent two-particle angular correlation function in proton-lead (pPb) collisions at a nucleon-nucleon center-of-mass energy of $\sqrt{s_\mathrm{NN}}$ = 8.16 TeV and lead-lead (PbPb) collisions at$\sqrt{s_\mathrm{NN}}$ = 5.02 TeV are reported. The pPb and PbPb datasets correspond to integrated luminosities of 186\nbinv and 0.607 nb$^{-1}$, respectively, and were collected using the CMS detector at the CERN LHC. The charge-dependent correlations are characterized by balance functions of same- and opposite-sign particle pairs. The balance functions, which contain information about the creation time of charged particle pairs and the development of collectivity, are studied as functions of relative pseudorapidity ($\Delta \eta$) and relative azimuthal angle ($\Delta \phi$), for various multiplicity and transverse momentum ($p_\mathrm{T}$) intervals. A multiplicity dependence of the balance function is observed in $\Delta \eta$ and $\Delta \phi$ for both systems. The width of the balance functions decreases towards high-multiplicity collisions in the momentum region $\lt$2 GeV, for pPb and PbPb results. No multiplicity dependence is observed at higher transverse momentum. The data are compared with HYDJET, HIJING and AMPT generator predictions, none of which capture completely the multiplicity dependence seen in the data

Probing small Bjorken-xx nuclear gluonic structure via coherent J/ψ\psi photoproduction in ultraperipheral PbPb collisions at sNN\sqrt{s_\mathrm{NN}} = 5.02 TeV

International audienceQuasi-real photons exchanged in relativistic heavy ion interactions are powerful probes of the gluonic structure of nuclei. The first measurement of the coherent J/$\psi$ photoproduction cross section in ultraperipheral lead-lead collisions is presented over a wide range of photon-nucleus center-of-mass energies per nucleon (W$^\text{Pb}_{\gamma\text{N}}$). Results are obtained using data at the nucleon-nucleon center-of-mass energy of 5.02 TeV collected by the CMS experiment at the CERN LHC, corresponding to an integrated luminosity of 1.52 nb$^{-1}$. The cross section is observed to rise rapidly at low W$^\text{Pb}_{\gamma\text{N}}$, and plateau above W$^\text{Pb}_{\gamma\text{N}}$$\approx$ 40 GeV, up to 400 GeV, a new regime of small Bjorken-$x$ ($\approx$ 6 $\times$ 10$^{-5}$) gluons being probed in a heavy nucleus. The observed energy dependence is not predicted by current quantum chromodynamic models