198 research outputs found
The temporal evolution of life satisfaction in institutionalized elderly: A longitudinal study
Diversidade de formigas (Hym., Formicidae) em dois sistemas distintos de cultivos de dendĂȘ Elaeis guineensis no Nordeste Paraense.
Atividade inseticida de extratos de nim (Azadirachta indica) sobre imaturos de Tenebrio molitor (Col., Curculionadae) em laboratĂłrio.
CondiçÔes topobioclimĂĄtica associadas Ă ocorrĂȘncia de taxi-branco (Sclerebium panuculatum Vogel) e paricĂĄ (Schzolobium parahyba var. amazonicum (huber ex Ducke) Barbeby) preferencias para implantação de plantios florestais no Estado do ParĂĄ.
Rare Primary Dyslipidaemias Associated with Low LDL and HDL Cholesterol Values in Portugal
Background: Dyslipidaemia represents a group of disorders of lipid metabolism, characterized by either an increase or decrease in lipid particles, usually associated with triglycerides, LDL cholesterol (LDL-C) and/or HDL cholesterol (HDL-C). Most hyperlipidaemias and HDL deficiencies confer an increased cardiovascular risk, while hypolipidaemia, such as abeta or hypobetalipoproteinemia, may present different manifestations ranging from poor weight progression to neurological manifestations. The aim of this study is to present 7 cases with rare dyslipidaemias associated with low LDL or low HDL cholesterol values, referred to our laboratory for the genetic identification of the cause of the dyslipidaemia. Methods: Lipid profile was determined for each individual in an automated equipment Integra Cobas (Roche). Molecular analysis was performed by NGS with a target panel of 57 genes involved in lipid metabolism (Sure select QXT, Agilent) and samples were run in a NextSEQ Sequencer (Illumina). Only genes associated to rare forms of low HDL-c or LDL-c were analysed for this work, namely: ABCA1, APOA1, LCAT, SCARB1, APOB, PCSK9, MTTP, SAR1B, and ANGPTL3. All rare variants (MAFA) and the other is a possible compound heterozygous for APOB variants c.2604+1G>A and c.4651C>T/p.(Gln1551*). In two patients only a variant in heterozygosity (c.3365delG/p.(Gly1122Vfs*62) and c.11095A>T/p.(Arg3699*)). In the remaining patient, no variants were identified. NGS proved to be a fundamental key for genetic testing of rare lipid disorders, allowing us to find the genetic cause of disease in 6/7 patients with low HDL-c and LDL-c. Patients with these rare conditions should be identified as early as possible in order to minimize or prevent clinical manifestations. The unsolved case is still under investigation.info:eu-repo/semantics/publishedVersio
Uso de ferramentas de automação e gerĂȘncia de dados de tempo e clima para subsidiar estudos agrometeorolĂłgicos na Embrapa AmazĂŽnia Oriental.
Zanthoxylum ekmanii espĂ©cie florestal promissora: estudo de caso em uma floresta explorada, no municĂpio de Dom Eliseu, ParĂĄ.
Plant communities as a tool in temporary ponds conservation in SW Portugal
Pond conservationTemporary ponds are seasonal wetlands
annually subjected to extreme and unstable ecological
conditions, neither truly aquatic nor truly terrestrial.
This habitat and its flora have been poorly
studied and documented because of the ephemeral
character of the flora, the changeable annual weather
that has a great effect on the small, herbaceous taxa
and the declining abundance of temporary ponds. The
objectives of this study are: (a) to define plant
community diversity in terms of floristic composition of ephemeral wetlands in SW Portugal, (b) to identify
temporary pond types according to their vegetation
composition and (c) to identify those ponds that
configure the European community priority habitat
(3170* â Mediterranean temporary ponds).
Vegetation sampling was conducted in 29 ponds,
identifying 168 species grouped among 15 plant
communities. Soil texture, pH, organic C and N
content were measured, but only N and percent of
clay appear to be related with the distribution of each
community type. The results showed that ephemeral
wetlands could be classified into four type: vernal
pools, marshlands, deep ponds and disturbed wetlands.
Vernal pools correspond to the Mediterranean
temporary ponds (3170*), protected as priority habitat
under the EU Habitats Directive. Submersed
Isoetes species (Isoetes setaceum and Isoetes velatum)
represents, together with Eryngium corniculatum,
the indicator species for vernal pools. We
identify also indicator plant communities of this
priority habitat, namely I. setaceum and E. corniculatumâ
Baldellia ranunculoides plant communities. In
this region, the conservation of temporary ponds has
so far been compatible with traditional agricultural
activities, but today these ponds are endangered by
the intensification of agriculture and the loss of
traditional land use practices and by the development
of touris
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