The Effect of Passive and Active Smoking on Nasal Mucociliary Clerarance Time

SIMSEK, GOKCE/0000-0001-5281-0986WOS: 000376566600001Aim: The aim of this study was to investigate the effect of passive and active smoking on NMC by comparing the results of age and sex matched healthy individuals, passive and active smokers. Material and Method: A total of 75 subjects met the criteria and were divided into three groups: control group (nonsmokers, group 1, n = 25), passive smokers group(group 2, n = 25), active smokers group (group 3, n = 25). NMC of these subjects were measured and compared. Moreover, the amount of cigarette consumption of active smokers group were calculated as package to year and the correlation between NMC and the amount of cigarette consumption. in active smokers group were evaluated. Results: The mean NMC in passive smokers group and active smokers group were significantly longer than the control group (p= 0,0001) The comparison of NMC values between the passive smokers group and the active smokers group revealed no statistically significant differences (p >= 0,05). There was positive correlation between the increase in NMC and amount of cigarette consumption in the active smokers group (p= 0,0001, r= 0.433). Discussion: Both active and passive smoking prolonged nasal mucociliary clearance time when they were compared with healthy controls. Tobacco exposure is associated diseases such as asthma, chronic rhinosinusitis, and lower airway infections. It may be related to the direct effect of prolonged NMC

Effects of valproic acid on hearing in epileptic patients

WOS: 000245418000016PubMed ID: 17270285Objective: Since some case reports about the ototoxicity of valproic acid have been published, probable adverse effects of valproic acid on hearing in the epileptic patients became a subject of interest. We wanted to investigate if ototoxicity occurs in pediatric epileptic patients using VPA for long terms. Methods: Twenty-one epileptic patients who have been using valproic acid at least for 6 months as monotherapy and 21 age-sex matched controls were included in the study. Audiometric tests were performed to all patients between the frequencies of 125 and 16,000 Hz. The effects of dosage, duration of therapy and serum levels of the VPA, on the audiometric results were investigated and the audiometric results were compared between the groups. Results: There was no difference in hearing thresholds of the groups between 125 and 16,000 Hz frequencies. Relation could not be established between the duration of VPA therapy, dosage of the drug, blood level of drug, age and sex of the patients and the auditory signs. Conclusions: Although we could not find any deleterious effect of VPA on hearing thresholds in our patient series, we think it is useful to perform audiometric tests at intervals while VPA is being used for tong periods, considering the presented case reports about sensorineural hearing loss. (c) 2007 Elsevier Ireland Ltd. All rights reserved

Dimensions of internal jugular veins in Turkish children aged between 0 and 6 years in resting state and during Valsalva maneuver

Objective: We aimed to establish the values of the internal jugular vein (IJV) sizes in Turkish children aged between 0 and 6 years

Evaluation of the turbinate hypertrophy by computed tomography in patients with deviated nasal septum

OBJECTIVES/HYPOTHESIS: To determine the dimensions of the compensatory hypertrophic inferior turbinate and investigate the radiological changes in the morphology of the conchal bone in patients with septal deviation

Plexiform neurofibroma of the tongue: a case report of a child

A three-year-old girl with a lingual plexiform neurofibroma treated by total excision is presented. Despite their occurrence in the head and neck region, neural sheath tumors are rarely encountered in the oral cavity. It is reported that 4-7% of patients affected by neurofibromatosis display oral manifestations. Neurofibromatosis is characterized by cafe-au-lait spots and cutaneous neurofibromas. Plexiform neurofibroma is said to be indicative of von Recklinghausen's disease (VRD) even though it may be the only manifestation of the disease. Generally, surgical resection represents the treatment of choice and the diagnosis can only be confirmed after histological examination. Affected patients need regular follow-up to detect malignant degeneration, an early recurrence or appearance of other manifestations of VRD

Evaluation of the turbinate hypertrophy by computed tomography in patients with deviated nasal septum

OBJECTIVES/HYPOTHESIS: To determine the dimensions of the compensatory hypertrophic inferior turbinate and investigate the radiological changes in the morphology of the conchal bone in patients with septal deviation

An unexpected diagnosis during laryngeal intubation: osseous polypoid lesion of the tongue: osteoma or choristoma?

Soft tissue osteoma is a rare entity having a strong predilection for the head and neck region, mainly posterior region of the tongue. The so-called lingual osteoma is mostly manifested as an asymptomatic exophytic lesion. It can be diagnosed by physical or radiological examinations

The Score For Allergic Rhinitis study in Turkey

WOS: 000295541500016PubMed ID: 22186248Background: The clinical definition of allergic rhinitis (AR) is difficult to use in epidemiological settings of large populations where it is impossible to obtain the laboratory evidence of each immune response. However, the standardization of the definition of AR in epidemiological studies is of crucial importance. This study was designed to estimate the prevalence of AR in an adult general population with respect to seven distinct geographical regions in Turkey. Methods: Individuals were evaluated with the Score for Allergic Rhinitis (SFAR) questionnaire for a national cross-sectional study. The Turkish version of the SFAR questionnaire was tested for clarity and sensitivity in a small sample of the general population. Results: Among the 3967 interviewed subjects, the overall prevalence of AR was 29.6%, with regional variations (from 21.0% in the southeastern Anatolia region to 36.1% in the Marmara region). The prevalence was higher in women and in urban area of residence. Conclusion: This national survey confirmed the elevated prevalence of AR in Turkey. Our findings may contribute to the formulation of the public health policy and development of preventive and therapeutic strategies for AR in eastern Europe. (Am J Rhinol Allergy 25, 333-337, 2011; doi: 10.2500/ajra.2011.25.3665