Holographic Bosonic Technicolor

We consider a technicolor model in which the expectation value of an additional, possibly composite, scalar field is responsible for the generation of fermion masses. We define the dynamics of the strongly coupled sector by constructing its holographic dual. Using the AdS/CFT correspondence, we study the S parameter and the phenomenology of the light technihadrons. We find that the S parameter is small over a significant region of the model's parameter space. The particle spectrum is distinctive and includes a nonstandard Higgs boson as well as heavier hadronic resonances. Technihadron masses and decay rates are calculated holographically, as a function of the model's parameters.Comment: 20 Pages, 4 eps figures, REVTex. Minor corrections and comments adde

Seiberg-Witten Description of the Deconstructed 6D (0,2) Theory

It has recently been suggested that, in a large N limit, a particular four dimensional gauge theory is indistinguishable from the six dimensional CFT with (0,2) supersymmetry compactified on a torus. We give further evidence for this correspondence by studying the Seiberg-Witten curve for the "deconstructed" theory and demonstrating that along the reduced Coulomb branch of moduli space (on the intersection of the Higgs and Coulomb branches) it describes the low energy physics on a stack of M5-branes on a torus, which is the (0,2) theory on a torus as claimed. The M-theory construction helps to clarify the enhancement of supersymmetry in the deconstructed theory at low energies, and demonstrates its stability to radiative and instanton corrections. We demonstrate the role of the theta vacuum in the deconstructed theory. We point out that by varying the theta parameters and gauge couplings in the deconstructed theory, the complex structure of the torus can be chosen arbitrarily, and the torus is not metrically S^1 x S^1 in general.Comment: 13 pages, 2 figure

Conformal Symmetry and the Three Point Function for the Gravitational Axial Anomaly

This work presents a first study of a radiative calculation for the gravitational axial anomaly in the massless Abelian Higgs model. The two loop contribution to the anomalous correlation function of one axial current and two energy-momentum tensors, , is computed at an order that involves only internal matter fields. Conformal properties of massless field theories are used in order to perform the Feynman diagram calculations in the coordinate space representation. The two loop contribution is found not to vanish, due to the presence of two independent tensor structures in the anomalous correlator.Comment: 34 pages, 5 figures, RevTex, Minor changes, Final version for Phys. Rev.

Deficits in Beam-Walking After Neonatal Motor Cortical Lesions are not Spared by Fetal Cortical Transplants in Rats

Adult rats that sustained unilateral motor cortical lesions at birth demonstrated deficits in traversing an elevated narrow beam. These deficits, manifested by hindlimb slips off the edge of the beam, were not spared in animals that received fetal cortical transplants into the lesion cavity immediately after lesion placement

Expression of factor V by resident macrophages boosts host defense in the peritoneal cavity

Macrophages resident in different organs express distinct genes, but understanding how this diversity fits into tissue-specific features is limited. Here, we show that selective expression of coagulation factor V (FV) by resident peritoneal macrophages in mice promotes bacterial clearance in the peritoneal cavity and serves to facilitate the well-known but poorly understood macrophage disappearance reaction. Intravital imaging revealed that resident macrophages were nonadherent in peritoneal fluid during homeostasis. Bacterial entry into the peritoneum acutely induced macrophage adherence and associated bacterial phagocytosis. However, optimal control of bacterial expansion in the peritoneum also required expression of FV by the macrophages to form local clots that effectively brought macrophages and bacteria in proximity and out of the fluid phase. Thus, acute cellular adhesion and resident macrophage-induced coagulation operate independently and cooperatively to meet the challenges of a unique, open tissue environment. These events collectively account for the macrophage disappearance reaction in the peritoneal cavity

A tubo-ovarian abscess mimicking an appendiceal abscess: a rare presentation of Streptococcus agalactiae.

A tubo-ovarian abscess (TOA) is a relatively rare medical complication that results from an untreated/unrecognized ascending pelvic infection of the female genital tract. In a right-sided TOA, this clinical entity may mimic appendicitis on computed tomography (CT). In addition, both disease processes can present with pelvic pain, leukocytosis and fever. We present the case of a 47-year-old female with mid right-sided abdominal pain that was diagnosed on CT scan with an appendiceal abscess. She underwent CT-guided percutaneous drainage with interventional radiology. On Day 8, a CT limited study involving a contrast injection was performed to evaluate for abscess resolution. The contrast within the drain filled the fallopian tube, endometrial cavity and contralateral fallopian tube. These findings demonstrated that the initial diagnosis actually represented a TOA. To the authors\u27 knowledge, this is the only reported case involving a TOA secondary to Streptococcus agalactiae (GBS) mimicking an appendicitis with abscess formation

Clustering and Alignment of Polymorphic Sequences for HLA-DRB1 Genotyping

Located on Chromosome 6p21, classical human leukocyte antigen genes are highly polymorphic. HLA alleles associate with a variety of phenotypes, such as narcolepsy, autoimmunity, as well as immunologic response to infectious disease. Moreover, high resolution genotyping of these loci is critical to achieving long-term survival of allogeneic transplants. Development of methods to obtain high resolution analysis of HLA genotypes will lead to improved understanding of how select alleles contribute to human health and disease risk. Genomic DNAs were obtained from a cohort of n = 383 subjects recruited as part of an Ulcerative Colitis study and analyzed for HLA-DRB1. HLA genotypes were determined using sequence specific oligonucleotide probes and by next-generation sequencing using the Roche/454 GSFLX instrument. The Clustering and Alignment of Polymorphic Sequences (CAPSeq) software application was developed to analyze next-generation sequencing data. The application generates HLA sequence specific 6-digit genotype information from next-generation sequencing data using MUMmer to align sequences and the R package diffusionMap to classify sequences into their respective allelic groups. The incorporation of Bootstrap Aggregating, Bagging to aid in sorting of sequences into allele classes resulted in improved genotyping accuracy. Using Bagging iterations equal to 60, the genotyping results obtained using CAPSeq when compared with sequence specific oligonucleotide probe characterized 4-digit genotypes exhibited high rates of concordance, matching at 759 out of 766 (99.1%) alleles. © 2013 Ringquist et al

Virtual Compton Scattering off a Spinless Target in AdS/QCD

We study the doubly virtual Compton scattering off a spinless target $\gamma^*P\to\gamma^*P'$ within the Anti-de Sitter(AdS)/QCD formalism. We find that the general structure allowed by the Lorentz invariance and gauge invariance of the Compton amplitude is not easily reproduced with the standard recipes of the AdS/QCD correspondence. In the soft-photon regime, where the semi-classical approximation is supposed to apply best, we show that the measurements of the electric and magnetic polarizabilities of a target like the charged pion in real Compton scattering, can already serve as stringent tests.Comment: 21 pages, version to be published in JHEP