Intersphincteric Resection and Coloanal Anastomosis in Treatment of Distal Rectal Cancer

In the treatment of distal rectal cancer, abdominoperineal resection is traditionally performed. However, the recognition of shorter safe distal resection line, intersphincteric resection technique has given a chance of sphincter-saving surgery for patients with distal rectal cancer during last two decades and still is being performed as an alternative choice of abdominoperineal resection. The first aim of this study is to assess the morbidity, mortality, oncological, and functional outcomes of intersphincteric resection. The second aim is to compare outcomes of patients who underwent intersphincteric resection with the outcomes of patients who underwent abdominoperineal resection

Interaction of Gut Flora and Bacterial Pathogens of Cultured Common Dentex (Dentex dentex)

This study was carried out to determine the population of gut flora and investigate the source of the pathogenic bacteria recovered from moribund dentex (Dentex dentex). Transmission electron microscopy (TEM) was used to monitor the translocation of bacterial pathogens which can enter the host through the gut. A total of 260 samples from larvae at different feeding stages were examined, 15 healthy and 50 moribund juvenile dentex were sampled over a 2-year period. Bacterial isolates (n=433) from healthy and moribund fish and their environments were identified by biochemical methods; 75% of them were identified as Gram-negative (mainly Vibrio spp.) and 25% as Gram-positive. Vibrio scophthalmi and other Vibrio species were recovered from moribund fish samples. Some bacteria were recovered from diseased fish reared in hatcheries, introduced mainly from sea water. Among anaerobic bacteria, Eubacterium tarantellae was recovered from larval gut flora while Clostridium botulinum was recovered from juvenile gut flora. TEM also showed that bacterial endocytosis first occurs when fish are fed granulated dry feeds and becomes more prevalent in the juvenile stages when many bacteria are present in the microvilli. TEM also revealed that the bacteria enter the larvae via the mouth and gills before the granulated feeding stage, after which they begin to penetrate the gut and finally also contaminate the marine rearing stage. The results of this study showed that the granulated feeding stage is critical for pathogen invasion in common dentex

Review Article Intersphincteric Resection and Coloanal Anastomosis in Treatment of Distal Rectal Cancer

In the treatment of distal rectal cancer, abdominoperineal resection is traditionally performed. However, the recognition of shorter safe distal resection line, intersphincteric resection technique has given a chance of sphincter-saving surgery for patients with distal rectal cancer during last two decades and still is being performed as an alternative choice of abdominoperineal resection. The first aim of this study is to assess the morbidity, mortality, oncological, and functional outcomes of intersphincteric resection. The second aim is to compare outcomes of patients who underwent intersphincteric resection with the outcomes of patients who underwent abdominoperineal resection

Ileocecal Intussusception due to a Lipoma in an Adult

While intestinal tumors are rare, small intestinal lipomas are even more uncommon benign neoplasms. They are usually asymptomatic, but lipomas larger than 2 cm may become symptomatic due to obstruction, bleeding, or intussusception. In this paper, US and CT findings of a lipoma located in the terminal ileum and causing ileocecal intussusception were discussed. We report a case of small bowel lipoma that became symptomatic due to intermittent obstruction episodes and ileocecal intussuception. If the diagnosis of intestinal lipoma had been made absolutely as in our case, they should be removed surgically in elective conditions

Interaction of Gut Flora and Bacterial Pathogens of Cultured Common Dentex (Dentex dentex)

This study was carried out to determine the population of gut flora and investigate the source of the pathogenic bacteria recovered from moribund dentex (Dentex dentex). Transmission electron microscopy (TEM) was used to monitor the translocation of bacterial pathogens which can enter the host through the gut. A total of 260 samples from larvae at different feeding stages were examined, 15 healthy and 50 moribund juvenile dentex were sampled over a 2- year period. Bacterial isolates (n=433) from healthy and moribund fish and their environments were identified by biochemical methods; 75% of them were identified as Gram- negative (mainly Vibrio spp.) and 25% as Gram- positive. Vibrio scophthalmi and other Vibrio species were recovered from moribund fish samples. Some bacteria were recovered from diseased fish reared in hatcheries, introduced mainly from sea water. Among anaerobic bacteria, Eubacterium tarantellae was recovered from larval gut flora while Clostridium botulinum was recovered from juvenile gut flora. TEM also showed that bacterial endocytosis first occurs when fish are fed granulated dry feeds and becomes more prevalent in the juvenile stages when many bacteria are present in the microvilli. TEM also revealed that the bacteria enter the larvae via the mouth and gills before the granulated feeding stage, after which they begin to penetrate the gut and finally also contaminate the marine rearing stage. The results of this study showed that the granulated feeding stage is critical for pathogen invasion in common dentex

Role of contrast-enhanced F-18-FDG PET/CT imaging in the diagnosis and staging of renal tumors

WOS: 000451811700015PubMed: 30234688Purpose the objectives of this prospective study are to compare intravenous contrast-enhanced (CE) fluorine-18-fluorodeoxyglucose (F-18-FDG) PET/computed tomography (CE F-18-FDG PET/CT) with conventional methods (CT/MRI) and to evaluate the relationship of maximum standardized uptake value (SUVmax) with Fuhrman grade in patients with renal tumors. Patients and methods A total of 62 patients [35 males and 27 females; mean age 55.8 +/- 12.7 (range: 27-81) years] were enrolled in the study. CE F-18-FDG PET/CT scanning included whole-body (early) and abdominal imaging (late) 1 and 2 h after intravenous F-18-FDG administration, respectively. SUVmax was calculated for primary tumors. CE F-18-FDG PET/CT and CT/MRI findings were compared with respect to primary tumors and staging. Results the sensitivity of CE F-18-FDG PET/CT in primary tumor detection was 98%, which was very close to that of CT/MRI (100%). CE F-18-FDG PET/CT resulted in correct staging in 84% of the cases, compared with 68% of the cases with conventional methods (52 vs. 42 patients). SUVmax values of early PET for the primary tumors were significantly correlated with the Fuhrman grades (P<0.001). CE F-18-FDG PET/CT enabled the detection of synchronous tumors in four patients, one of which was incorrectly diagnosed as having metastasis by CT. Distant metastases were detected in 16 patients with CE F-18-FDG PET/CT and in 13 patients with routine conventional methods. Conclusion CE F-18-FDG PET/CT showed similar results compared with CT/MRI in the detection of primary tumors, but it was superior to conventional methods in the detection of metastasis and staging. Given the highly significant correlation between SUVmax values and the Fuhrman grading, CE F-18-FDG PET/CT may play a significant role in the evaluation of patient prognosis