Mindfulness Training Encourages Self-Transcendent States via Decentering

Self-transcendence is theorized to be a core, mechanism of mindfulness. Yet, no known empirical study has investigated the process by which self-transcendent experiences emerge in novice practitioners. To address this gap, this study explored whether changes in decentering in response to mindfulness training translated into increases in self-transcendence over the course of five mindfulness training sessions. Participants (N=26) were randomly allocated to either a mindfulness training condition or an active listening condition. Results indicated that mindfulness training increased both decentering (p=.023) and self-transcendence (p=.001) relative to the active listening condition. Furthermore, greater decentering at the mid-point of training predicted greater self-transcendence at the training’s end, suggesting that those participants that become better able to non-reactively observe their thoughts, feelings and physical sensations while meditating were also more likely to experience self-transcendence. This study provides the first empirical evidence that mindfulness training can cultivate self- transcendent experiences through the process of decentering from internal phenomena

Biopsychosocial Assessment of a Mindfulness-Oriented Cognitive Intervention for Alcohol Dependent Adults

A biopsychosocial approach is needed to comprehend the complex pathogenic processes implicated in alcohol dependence. The following three papers employ such an approach to explore key research questions: (a) How might stress precipitate alcohol misuse, dependence, and relapse, and (b) How can targeted psychosocial interventions influence this process? The first paper presents a novel conceptual framework integrating formerly discrete theories of stress appraisal, neurobiological allostasis, automatic cognitive processing, and addictive behavior to explain how alcohol misuse and dependence is maintained and re-activated by stress. This theoretical framework underpins the measurement model and intervention that are the focus of the second and third papers. The second paper explores relationships between baseline dispositional mindfulness and alcohol attentional bias among a sample of recovering alcohol dependent adults, relationships that are critical to our argument in support of mindfulness training as a treatment for alcohol dependence. The third paper in this series is a report of a randomized controlled pilot trial comparing the effects of a mindfulness-oriented intervention to those of an alcohol dependence support group. Results from this study provide tentative support for the proposed theoretical framework and for the use of mindfulness as a treatment for alcohol dependence

Random Encounter and Staying Time Model Testing with Human Volunteers

Ecology and management programs designed to track population trends over time increasingly are using passive monitoring methods to estimate terrestrial mammal densities. Researchers use motion‐sensing cameras in mammal studies because they are cost‐effective and advances in statistical methods incorporate motion‐sensing camera data to estimate mammal densities. Density estimation involving unmarked individuals, however, remains challenging and empirical tests of statistical models are relatively rare. We tested the random encounter and staying time model (REST), a new means of estimating the density of an unmarked population, using human volunteers and simulated camera surveys. The REST method produced unbiased estimates of density, regardless of changes in human abundance, movement rates, home range sizes, or simulated camera effort. These advances in statistical methods when applied to motion‐sensing camera data provide innovative avenues of large‐mammal monitoring that have the potential to be applied to a broad spectrum of conservation and management studies, provided assumptions for the REST method are rigorously tested and met

Mindful Lawyering: a Pilot Study on Mindfulness Training for Law Students

Many US law schools are now offering elective courses in mindfulness training to alleviate disproportionately high levels of anxiety, depression, stress, and disordered alcohol use among law students. To date, empirical evidence on the effectiveness of these courses has been lacking. The aim of this pilot study was to explore the feasibility and impact of a 13-week mindfulness course, Mindful Lawyering, specifically tailored to law students. The primary hypothesis was that mindfulness training would be significantly correlated with improvements in well-being and mindfulness

An Integrated Mechanistic Model of Mindfulness-Oriented Recovery Enhancement for Opioid-Exposed Mother–Infant Dyads

A growing body of neurobiological and psychological research sheds light on the mechanisms underlying the development and maintenance of opioid use disorder and its relation to parenting behavior. Perinatal opioid use is associated with risks for women and children, including increased risk of child maltreatment. Drawing from extant data, here we provide an integrated mechanistic model of perinatal opioid use, parenting behavior, infant attachment, and child well-being to inform the development and adaptation of behavioral interventions for opioid-exposed mother–infant dyads. The model posits that recurrent perinatal opioid use may lead to increased stress sensitivity and reward dysregulation for some mothers, resulting in decreased perceived salience of infant cues, disengaged parenting behavior, disrupted infant attachment, and decreased child well-being. We conclude with a discussion of Mindfulness-Oriented Recovery Enhancement as a means of addressing mechanisms undergirding perinatal opioid use, parenting, and attachment, presenting evidence on the efficacy and therapeutic mechanisms of mindfulness. As perinatal opioid use increases in the United States, empirically informed models can be used to guide treatment development research and address this growing concern

Mindfulness in Treatment Approaches for Addiction — Underlying Mechanisms and Future Directions

Purpose of Review: While the treatment of addictive disorders proves to be challenging, new treatment approaches that evolved around the concepts of mindfulness and acceptance have been utilized and investigated in recent years. Our goal is to summarize the efficacy and possible underlying mechanisms of mindfulness-based interventions (MBI) in addictive disorders. Recent Findings: Various meta-analyses have suggested that MBIs show clinical efficacy in the treatment of addictive disorders. Considering the factors that impact addictive disorders, MBIs have been indicated to augment responsiveness to natural rewards in contrast to addiction-related cues as well as to increase top-down cognitive control, decrease subjective and physiological stress perception, and enhance positive affect. Summary: In summary, MBIs hold promise in treating addictive disorders while larger randomized controlled trials with longitudinal study designs are needed to confirm their utility. Newest clinical endeavors strive to enhance the clinical utility of MBIs by augmentation or personalization

Mindfulness-Oriented Recovery Enhancement versus CBT for co-occurring substance dependence, traumatic stress, and psychiatric disorders: Proximal outcomes from a pragmatic randomized trial

In clinical settings, there is a high comorbidity between substance use disorders, psychiatric disorders, and traumatic stress. As such, transdiagnostic therapies are needed to address these co-occurring issues efficiently. The aim of the present study was to conduct a pragmatic randomized controlled trial comparing Mindfulness-Oriented Recovery Enhancement (MORE) to group Cognitive-Behavioral Therapy (CBT) and treatment-as-usual (TAU) for previously homeless men residing in a therapeutic community. Men with co-occurring substance use and psychiatric disorders, as well as extensive trauma histories, were randomly assigned to 10 weeks of group treatment with MORE (n=64), CBT (n=64), or TAU (n=52). Study findings indicated that from pre- to post-treatment MORE was associated with modest yet significantly greater improvements in substance craving, post-traumatic stress, and negative affect than CBT, and significantly greater improvements in post-traumatic stress and positive affect than TAU. A significant indirect effect of MORE on decreasing craving and post-traumatic stress by increasing dispositional mindfulness was observed, suggesting that MORE may target these issues via enhancing mindful awareness in everyday life. This pragmatic trial represents the first head-to-head comparison of MORE against an empirically-supported treatment for co-occurring disorders. Results suggest that MORE, as an integrative therapy designed to bolster self-regulatory capacity, may hold promise as a treatment for intersecting clinical conditions

Deficits in autonomic indices of emotion regulation and reward processing associated with prescription opioid use and misuse

Prescription opioid misuse and high dose opioid use may result in allostatic dysregulation of hedonic brain circuitry, leading to reduced emotion regulation capacity. In particular, opioid misuse may blunt the ability to experience and upregulate positive affect from natural rewards

Mindfulness-based treatment of addiction: current state of the field and envisioning the next wave of research

Abstract Contemporary advances in addiction neuroscience have paralleled increasing interest in the ancient mental training practice of mindfulness meditation as a potential therapy for addiction. In the past decade, mindfulness-based interventions (MBIs) have been studied as a treatment for an array addictive behaviors, including drinking, smoking, opioid misuse, and use of illicit substances like cocaine and heroin. This article reviews current research evaluating MBIs as a treatment for addiction, with a focus on findings pertaining to clinical outcomes and biobehavioral mechanisms. Studies indicate that MBIs reduce substance misuse and craving by modulating cognitive, affective, and psychophysiological processes integral to self-regulation and reward processing. This integrative review provides the basis for manifold recommendations regarding the next wave of research needed to firmly establish the efficacy of MBIs and elucidate the mechanistic pathways by which these therapies ameliorate addiction. Issues pertaining to MBI treatment optimization and sequencing, dissemination and implementation, dose–response relationships, and research rigor and reproducibility are discussed