Bronşektazide Hava Yolu Kolonizasyonu Sistemik Inflamasyona Neden Olur Mu?

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Smooth Muscle Hyperplasia In An Asthmatic Patient: Do We Know It All?

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Pulmonary Embolism Due To Metal Coil: Case Report

Radiological studies may sometimes reveal unexpected findings. A 42-year-old male patient was referred to our center because of metallic opacities observed on the chest X-ray. Physical examination was unremarkable except for macular lesions on both lower extremities. A detailed medical history revealed that the patient had a varicocele in the right testis which was obliterated with coil embolization 12 years ago. The metallic opacities observed on the chest X-ray were considered to result from the migration of the coils from testis to the lungs. Coil embolization is an effective and safe procedure in the treatment of varicocele. However, as presented in the case, the procedure may cause complications in a certain subgroup of patients. Migration of coils from the varicose testicular veins to the pulmonary vessels may be clinically insignificant; however, when found incidentally, it may pose a diagnostic problem that needs to be solved by the clinician.WoSScopu

Endobronchial lipoma in a patient with Churg-Strauss syndrome

Churg-Strauss syndrome (CSS) is a disorder characterized by hypereosinophilia and systemic vasculitis complicating a preexisting asthma. We report here a case of CSS with an endobronchial lesion, initially considered to be an endobronchial granuloma of CSS, which was finally diagnosed as a lipoma, a very rare benign tumor of the tracheobronchial tree. To our knowledge, this is the first case in the literature presenting with these two rare entities

Splenic Artery Embolization: An Alternative Approach In A Critically Ill Patient With Autoimmune Hemolytic Anemia

Assessment of general health status and hematological parameters usually precedes the use of invasive diagnostic and therapeutic procedures in critically ill patients. Angiography can be effective and safe as a substitute for major surgical procedures, or as a bridging therapy in such cases. We present a critically ill patient with hemolytic anemia that underwent splenic artery embolization as a bridging therapy. We aimed to emphasize that minimally invasive approaches and multidisciplinary care can be utilized in the treatment of critically ill patients with accompanying hematological disease. (Turk J Hematol 2011; 28: 135-8)WoSScopu

Respiratory symptoms and functions in tea workers

Respiratory symptoms and function tests were studied in tea workers and in a control group. The prevalance of acute and chronic respiratory symptoms were not different in two groups except for an acute burning sensation of eye-nose-throat and a chronic cough. Also the comparison of the respiratory function tests between tea workers (both smokers and nonsmokers) and the controls were not different at preshift and postshift 30th minute and 8th hour. When preshift and postshift results were compared in tea workers ( both in smokers and nonsmokers); statistically significant reductions of FEV1, FEV1/FVC, FEF25-75 and FEF25 were seen at the postshift values. However statistically significant reductions were not observed in controls. Thus we conclude acute tea dust exposure may cause bronchial obstruction particularly in small airways

Hyponatremic Encephalopathy After Excessive Water Ingestion Prior To Pelvic Ultrasound: Neuroimaging Findings

We report two patients with acute hyponatremic encephalopathy which developed after massive water ingestion for pelvic ultrasound and emphasize the findings of magnetic resonance (MR) imaging including diffusion-weighted imaging (DWI). Both subjects had completely recovered within 24 hours following fluid restriction and salt replacement. MR imaging revealed cortical sulcal narrowing, restricted diffusion and sulcal T2 hyperintensity along with diffuse pial enhancement suggesting diffuse cerebral cortical cytotoxic edema and blood-brain barrier breakdown. In addition to the first illustration of multimodality MR imaging features of water-intoxication, these two cases also highlight the need for standardized practice on the quantity of water intake recommended to distend the bladder for pelvic ultrasound, especially in patients at risk for serum inappropriate ADH syndrome-related hyponatremia.WoSScopu

Childhood Onset Analgesic Intolerance: A Marker For Bronchial-Asthma In Adulthood?

Analgesic intolerance (AI) which is classically known as a disease of the middle-aged adults, not uncommonly starts in childhood. In this study we sought to identify the characteristics of childhood onset Al and evaluated its association with the development of asthma. Among 729 analgesic intolerant patients followed in our institution between January 1991 and July 2004, 50 (16 mate, 34 female, 6.8% of the total Al population) had history of Al starting before the age of 18. The prevalence of asthma was 24% in childhood and increased to 40% during adulthood. Atopy was more common in patients with bronchial asthma (p < 0.05). The mean (+/- SD) age of onset for asthma (18.6 +/- 9.7years) was significantly greater than the onset of both rhinitis and Al (13.0 +/- 6.5 and 13.2 +/- 4.0 years, respectively). This finding is different than the chronology of events reported in the literature for adult onset Al patients, in which rhinitis and asthma usually precede the development of Al. The presence of such a difference in the sequence of disease patterns may be a clue for the pathophysiologic differences underlying childhood and adult onset Al. The role of childhood onset Al as a risk factor for developing for asthma in adulthood should be further assessed in prospective patient cohorts. (c) 2008 Elsevier Ltd. All rights reserved

Non-Steroidal Anti-Inflammatory Drug Hypersensitivity In Adults And The Factors Associated With Asthma

Background: Characteristics of non-steroidal anti-inflammatory drug (NSAID)-hypersensitivity (NH) associated with underlying/accompanying diseases has not been studied in Turkey. In addition, the factors associated with asthma in NH patients are not well known. The present study aimed to investigate the relationship between NH and chronic urticaria, rhinitis/rhinosinusitis, and asthma in an effort to identify NH phenotypes. The study's secondary aim was to identify the factors associated with asthma in NH patients and the NSAID reaction pattern in asthmatics. Methods: Data for 1137 NH patients in our hospital's allergy clinic database were retrospectively analyzed. Patients were divided into 5 groups based on their accompanying diseases (chronic urticaria, asthma, rhinitis/rhinosinusitis). Asthmatic patients were compared to non-asthmatic patients to identify the factors associated with asthma. Results: Reaction patterns and patient characteristics in each group differed from those in the reference group (NH only group). Asthma in patients with NH was associated with female gender, sinonasal polyposis/polyp surgery, rhinitis/rhinosinusitis, NSAID-induced rhinitis/asthma or a blended reaction pattern, immediate reaction following NSAID intake, self-reported history of food allergy, and family history of asthma; the odds ratios and 95% CIs were 1.35 (1.02-1.78), 13.52 (8.74-20.9)/10.94 (6.73-17.77), 12.06 (9-16.17), 15.28 (10.45-22.36)/2.43 (1.70-3.45), 1.76 (1.31-2.35), 1.49 (1.04-2.14), and 3.1 (2.35-4.08), respectively. The characteristics of the asthmatic patients that had urticaria/angioedema-type reactions to NSAID intake (pseudo Samter's syndrome) differed from those in the asthmatics with rhinitis/asthma-type reactions. Conclusions: Chronic urticaria, rhinitis, and asthma commonly accompany NH. NSAID response patterns in NH patients may help differentiate groups of patients. The present study identified factors associated with asthma in NH patients and observed that there seems to be different phenotypes of Samter's syndrome, for which a new classification scheme was proposed. (C) 2013 Elsevier Ltd. All rights reserved.WoSScopu