G03-1501 Prudent Use of Antibiotics in Companion Animals

This NebGuide explains why antibiotics must be used with care and how to prudently use antibiotics to treat companion animals. Antibiotics are used to improve animal health and performance. You, as the animal owner or caregiver, make important decisions about how antibiotics are finally used in companion animals. Antibiotics should be used prudently to ensure they are effective and will continue to benefit man and animals in the future. Are you prepared to make the best decisions about using antibiotics in animals

G03-1485 Guidelines for the Prudent Use of Antibiotics in Food Animals

This NebGuide explains why antibiotics must be used with care and how to prudently use antibiotics to treat food animals. Antibiotics are used to improve animal health and productivity. You, the animal caregiver, make important decisions about how antibiotics are finally used in food producing animals. Antibiotics should be used prudently to ensure they are effective, do not leave residues in food, and will continue to benefit man and animals in the future. Are you prepared to make the best decisions about using antibiotics in animals

The Effect of Bone and Analytical Methods on the Assessment of Bone Mineralization Response to Dietary Phosphorus, Phytase, and Vitamin D in Nursery Pigs

Three hundred-fifty pigs (initially 26.2 ± 1.23 lb) were used to evaluate the effects of bone and analytical methods on the assessment of bone mineralization response to dietary P and vitamin D in nursery pigs. Pens of pigs (5 or 6 pigs/pen) were randomized to 6 dietary treatments in a randomized complete block design with 10 pens per treatment. Treatments were formulated to have varying levels of P, phytase, and vitamin D to provide differences in bone characteristics. After feeding diets for 28 d, eight pigs per treatment were euthanized for bone, blood, and urine analysis. The response to treatment for bone density and ash was dependent upon the bone analyzed (density × bone interaction, P = 0.044; non-defatted bone ash × bone interaction, P = 0.060; defatted bone ash × bone interaction, P = 0.068). Pigs fed 0.19% STTD P had decreased (P \u3c 0.05) bone density and ash (non-defatted and defatted) for all bones compared to 0.44% STTD P, with 0.33% STTD P generally intermediate or similar to 0.44% STTD P. Pigs fed 0.44% STTD P with no vitamin D had greater (P \u3c 0.05) non-defatted fibula ash compared to all treatments other than 0.44% STTD P with added HyD. Pigs fed the three diets with 0.44% STTD P had greater (P \u3c 0.05) defatted 2nd rib ash compared to pigs fed 0.19% STTD P or 0.33% STTD P with no phytase. In summary, bone density and ash responses varied depending on the bone analyzed. Differences in bone density and ash in response to P and vitamin D were most apparent with fibulas and 2nd ribs. The difference between bone ash procedures was more apparent than the differences between treatments. For histopathology, 10th ribs were more sensitive than 2nd ribs or fibulas for detection of lesions

The Effect of Different Bone and Analytical Methods on the Assessment of Bone Mineralization to Dietary Phosphorus, Phytase, and Vitamin D in Finishing Pigs

Eight hundred eighty-two pigs (initially 73.2 ± 0.7 lb) were used to evaluate the effects of different bones and analytical methods on the assessment of bone mineralization response to dietary P and vitamin D in growing-finishing pigs. Pens of pigs (20 pigs per pen) were randomized to 1 of 5 dietary treatments in a completely randomized design with 9 pens per treatment. Treatments were formulated to have varying levels of P, phytase, and vitamin D to potentially provide wide differences in bone characteristics. After feeding diets for 112 d, nine pigs per treatment were euthanized for bone, blood, and urine analysis. There were no significant differences for final BW, ADG, ADFI, F/G (P \u3e 0.10), or bone ash (bone ash × bone interaction, P \u3e 0.10) regardless of the ashing method. The response to treatment for bone density and bone mineral content was dependent upon the bone (density interaction, P = 0.053; mineral interaction, P = 0.078). There were no treatment differences for bone density and bone mineral content for metacarpals, fibulas, and 2nd rib (P \u3e 0.05). For 10th rib bone density, pigs fed industry levels of P and vitamin D had increased (P \u3c 0.05) bone density compared to pigs fed NRC levels with phytase, with pigs fed deficient P, NRC levels of P with no phytase, and extra 25(OH)D3 vitamin D (HyD) intermediate. Pigs fed extra vitamin D from HyD had increased (P \u3c 0.05) 10th rib bone mineral content compared to pigs fed deficient P and NRC levels of P with phytase, with pigs fed industry P and vitamin D, and NRC P with monocalcium intermediate. In summary, bone density and bone mineral content responses varied depending on the bone. The difference between bone ash procedures was more apparent than the differences between diets. Differences in bone density and mineral content in response to P and vitamin D were most apparent with the 10th ribs

G03-1514 Use of Feed Contaminated with Fungal (Mold) Toxins (Mycotoxins)

Mycotoxins are chemicals produced by fungi (molds) under certain conditions. They are not essential for fungal growth or reproduction, and they are toxic to animals or humans. They are naturally occurring chemicals found in grains, food and feed consumed by humans and animals and cannot be completely avoided. Accordingly, we try to control the amount of such chemicals ingested by humans and animals. The purpose of this NebGuide is to provide guidelines on use of mycotoxin-contaminated feeds

Post Mortem Copper Concentrations in the Liver of Feedlot Steers Fed Condensed Corn Distillers Solubles

Condensed corn distillers solubles fed over an extended period may have some impact on liver tissue copper concentration due to the high sulfur content of this feedstuff. However, if the total ration concentration of sulfur is maintained below 0.30 percent of the diet as dry matter intake there does not seem to be any adverse effect in steers in terms of causing brain lesions.</p

Multilaboratory Survey To Evaluate Salmonella Prevalence in Diarrheic and Nondiarrheic Dogs and Cats in the United States between 2012 and 2014.

Eleven laboratories collaborated to determine the periodic prevalence of Salmonella in a population of dogs and cats in the United States visiting veterinary clinics. Fecal samples (2,965) solicited from 11 geographically dispersed veterinary testing laboratories were collected in 36 states between January 2012 and April 2014 and tested using a harmonized method. The overall study prevalence of Salmonella in cats (3 of 542) was &lt;1%. The prevalence in dogs (60 of 2,422) was 2.5%. Diarrhea was present in only 55% of positive dogs; however, 3.8% of the all diarrheic dogs were positive, compared with 1.8% of the nondiarrheic dogs. Salmonella-positive dogs were significantly more likely to have consumed raw food (P = 0.01), to have consumed probiotics (P = 0.002), or to have been given antibiotics (P = 0.01). Rural dogs were also more likely to be Salmonella positive than urban (P = 0.002) or suburban (P = 0.001) dogs. In the 67 isolates, 27 unique serovars were identified, with three dogs having two serovars present. Antimicrobial susceptibility testing of 66 isolates revealed that only four of the isolates were resistant to one or more antibiotics. Additional characterization of the 66 isolates was done using pulsed-field gel electrophoresis and whole-genome sequencing (WGS). Sequence data compared well to resistance phenotypic data and were submitted to the National Center for Biotechnology Information (NCBI). This study suggests an overall decline in prevalence of Salmonella-positive dogs and cats over the last decades and identifies consumption of raw food as a major risk factor for Salmonella infection. Of note is that almost half of the Salmonella-positive animals were clinically nondiarrheic