13 research outputs found
Asian fertility transition
Katedra demografie a geodemografieDepartment of Demography and GeodemographyFaculty of SciencePĹ™ĂrodovÄ›decká fakult
Fertility decline below replacement fertility in Asian countries
Fertility has been declining very rast most countries orthe world over tbe past 40 years, and it continues to decline almost everywhere. As a result, rertility has reached quite unexpectedly low levels in many countries. Currently, about halr or tbe world's population is living in countries witb rertility at, or below replacement levels. The paper concentrates on tbe present rertility decline in some Asian countries, because it has largely c1ĂŤaracterized the Asian population transition over the later part or tbe last century. Beginning witb tbe initiation or Japan's transition in the 1930s, rertility declines in other Asian countries soon rollowed, with levels in Hong Kong, Taiwan and Singapore beginning to rall by the 1960s. The latter part orthe 1960s and the 1970s heralded the beginning or transitions in the major Chinese and Soutb Korean cities, as well as the Chinese populations in Southeast Asia.13513
Asian fertility transition
Katedra demografie a geodemografieDepartment of Demography and GeodemographyFaculty of SciencePĹ™ĂrodovÄ›decká fakult
Effect of <i>Mycoplasma hominis</i> and cytomegalovirus infection on pregnancy outcome: A prospective study of 200 Mongolian women and their newborns
<div><p>In Mongolia, diagnostic tests for the detection of the sexually transmitted mycoplasmas, ureaplasmas, Herpes simplex virus (HSV), and cytomegalovirus (CMV) are currently not routinely used in clinical settings and the frequency of these STIs are enigmatic. The prevalence of these STI pathogens were prospectively evaluated among 200 Mongolian pregnant women and their newborns and correlated with pregnancy outcome. TaqMan PCRs were used to detect bacterial and viral STI pathogens in pre-birth vaginal swabs of the pregnant women and in oral swabs of their newborns. A standardized questionnaire concerning former and present pregnancies was developed and linear regression analysis was used to correlate pathogen detection with pregnancy outcome. Ureaplasmas were the most prevalent of the tested pathogens (positive in 90.5% positive women and 47.5% newborns), followed by mycoplasmas (32.5% and 7.5%), chlamydia (14.5% and 7.5%), trichomonas (8.5% and 4.0%) and gonococcus (0.5% and 0%). CMV was found in 46.5% of the pregnant women and in 10.5% of their newborns, whereas HSV-2 was detected in only two mothers. Multiple regression analyses indicate that colonization of the mothers with <i>U</i>. <i>urealyticum</i>, <i>M</i>. <i>hominis</i>, <i>T</i>. <i>vaginalis</i> or CMV is associated with transmission to newborns and that transmission of <i>M</i>. <i>hominis</i> or CMV from Mongolian pregnant women to offspring is associated with reduced neonatal length and gestational age. Thus, diagnostic tests for their detection should be implemented in the clinical settings in Mongolia.</p></div
Characteristics of 200 pregnant women from Mongolia, Ulaanbaatar.
<p>Characteristics of 200 pregnant women from Mongolia, Ulaanbaatar.</p
STI-pathogen load in mothers and their newborns.
<p>Quantities of each pathogen were normalized to human cells (pathogen-GE /10<sup>6</sup> GAPDH-GE) and the mean (+/- standard deviation) of the 200 values of mothers (_M) and newborns (_N) depicted as (x+1) to visualize even the negative detections in column scatter plot.</p
Co-localizing STI pathogens.
<p>Stacked bar charts indicate the decreasing number of specimens (with respect to the maternal colonization; from left) with detected pathogens and pathogen-communities in the 200 maternal vaginal specimens (Mothers) and 200 neonatal oral specimens (Newborns). Abbreviations indicate the respective microorganisms: Up, <i>U</i>. <i>parvum</i>, Uu, <i>U</i>. <i>urealyticum</i>; Mh, <i>M</i>. <i>hominis</i>; Mg, <i>M</i>. <i>genitalium</i>; Ct, <i>C</i>. <i>trachomatis</i>, Tv, <i>T</i>.<i>vaginalis</i>; and CM, CMV.</p
Quantities of <i>M</i>. <i>hominis</i>, CMV and <i>U</i>. <i>parvum</i> with respect to gestational age.
<p>Column scatter plots indicate the mean genome equivalents of <i>M</i>. <i>hominis</i>, CMV and <i>U</i>. <i>parvum</i> in maternal and neonatal specimens, normalized to 10<sup>6</sup> GAPDH genome equivalents, in 2 GA -weeks intervals from 35–36 to 39–40. Statistically significant differences were assessed by Kruskal-Wallis test between GA-groups 35–36 and 38–39 or 39–40, respectively (p-values < 0,05).</p
Correlation of pathogen load and pregnancy outcome.
<p>Correlation of pathogen load and pregnancy outcome.</p