255 research outputs found

    Sentiment Sentence Extraction Using a Hierarchical Directed Acyclic graph Structure and Bootstrap Approach

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    PACLIC / The University of the Philippines Visayas Cebu College Cebu City, Philippines / November 20-22, 200

    Multi-aspects Review Summarization Based on Identification of Important Opinions and their Similarity

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    Combination of 3 Types of Speech Recognizers for Anaphora Resolution

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    An Effective Speech Understanding Method with a Multiple Speech Recognizer based on Output Selection using Edit Distance

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    PACLIC / The University of the Philippines Visayas Cebu College Cebu City, Philippines / November 20-22, 200

    Split Generation in the SUSY Mass Spectrum and B_s-{\bar B}_s Mixing

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    We show that the like-sign di-muon anomaly reported recently by the D0 Collaboration can be explained in the supersymmetric standard model (SM) if the squarks and the sleptons in the first two generations have relatively small, but degenerate mass spectrum, and those in the third generation are larger as O(1-10)TeV. This split generation model provides large contributions to the B_s-{\bar B}_s mixing, although most of the FCNC's are suppressed due to the large masses of the third generation squarks or the GIM mechanism partially acting on the first and second generations.Comment: 15 pages, 1 figur

    An azoospermic factor gene, Ddx3y and its paralog, Ddx3x are dispensable in germ cells for male fertility

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    Takafumi MATSUMURA, Tsutomu ENDO, Ayako ISOTANI, Masaki OGAWA, Masahito IKAWA, An azoospermic factor gene, Ddx3y and its paralog, Ddx3x are dispensable in germ cells for male fertility, Journal of Reproduction and Development, 2019, Volume 65, Issue 2, Pages 121-128, Released April 12, 2019, [Advance publication] Released January 07, 2019, Online ISSN 1348-4400, Print ISSN 0916-8818, https://doi.org/10.1262/jrd.2018-145, https://www.jstage.jst.go.jp/article/jrd/65/2/65_2018-145/_article/-char/e

    Periodic production of retinoic acid by meiotic and somatic cells coordinates four transitions in mouse spermatogenesis

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    Mammalian spermatogenesis is an elaborately organized differentiation process, starting with diploid spermatogonia, which include germ-line stem cells, and ending with haploid spermatozoa. The process involves four pivotal transitions occurring in physical proximity: spermatogonial differentiation, meiotic initiation, initiation of spermatid elongation, and release of spermatozoa. We report how the four transitions are coordinated in mice. Two premeiotic transitions, spermatogonial differentiation and meiotic initiation, were known to be coregulated by an extrinsic signal, retinoic acid (RA). Our chemical manipulations of RA levels in mouse testes now reveal that RA also regulates the two postmeiotic transitions: initiation of spermatid elongation and spermatozoa release. We measured RA concentrations and found that they changed periodically, as also reflected in the expression patterns of an RA-responsive gene, STRA8; RA levels were low before the four transitions, increased when the transitions occurred, and remained elevated thereafter. We found that pachytene spermatocytes, which express an RA-synthesizing enzyme, Aldh1a2, contribute directly and significantly to RA production in testes. Indeed, chemical and genetic depletion of pachytene spermatocytes revealed that RA from pachytene spermatocytes was required for the two postmeiotic transitions, but not for the two premeiotic transitions. We conclude that the premeiotic transitions are coordinated by RA from Sertoli (somatic) cells. Once germ cells enter meiosis, pachytene spermatocytes produce RA to coordinate the two postmeiotic transitions. In combination, these elements underpin the spatiotemporal coordination of spermatogenesis and ensure its prodigious output in adult males

    Eluding the Gravitino Overproduction in Inflaton Decay

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    It is known that gravitinos are non-thermally produced in inflaton decay processes, which excludes many inflation models for a wide range of the gravitino mass. We find that the constraints from the gravitino overproduction can be greatly relaxed if the supersymmetry breaking field is much lighter than the inflaton, and if the dynamical scale of the supersymmetry breaking is higher than the inflaton mass. In particular, we show that many inflation models then become consistent with the pure gravity mediation with O(100)TeV gravitino which naturally explains the recently observed Higgs boson mass of about 125GeV.Comment: 19 pages, 2 figures; to appear in Phys.Lett.
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