Gaia Data Release 2: Validation of the classification of RR Lyrae and Cepheid variables with the Kepler and K2 missions

The second data release of the Gaia mission includes an advance catalog of variable stars. The classification of these stars are based on sparse photometry from the first 22 months of the mission. We set out to investigate the purity and completeness of the all-sky Gaia classification results with the help of the continuous light curves of the observed targets from the Kepler and K2 missions, focusing specifically on RR Lyrae and Cepheid pulsators, outside the Galactic Bulge region. We crossmatched the Gaia identifications with the observations collected by the Kepler space telescope. We inspected the light curves visually, then calculated the relative Fourier coefficients and period ratios for the single- and double-mode K2 RR Lyrae stars to further classify them. We identified 1443 and 41 stars classified as RR Lyrae or Cepheid variables in Gaia DR2 in the targeted observations of the two missions and 263 more RR Lyre targets in the Full-Frame Images (FFI) of the original mission. We provide the crossmatch of these sources. We conclude that the RR Lyrae catalog has a completeness between 70-78%, and provide a purity estimate between 92-98% (targeted observations) with lower limits of 75% (FFI stars) and 51% (K2 worst-case scenario). The low number of Cepheids prevents us from drawing detailed conclusions but the purity of the DR2 sample is estimated to be around 66%.Comment: 15 pages, 12 figures, 10 tables, accepted into the Gaia DR2 Special Issue in A&A. V1: submitted version, v2: accepted version. Lists available at http://konkoly.hu/~lmolnar/gaiakepler_datafiles_R1.zi

SIGNIFICANCE OF YEASTS IN BLOODSTREAM INFECTION: EPIDEMIOLOGY AND PREDISPOSING FACTORS OF CANDIDAEMIA IN ADULT PATIENTS AT A UNIVERSITY HOSPITAL (2010-2014)

The incidence of Candida bloodstream infection (BSI) has increased during the past decades. Species distribution is changing worldwide, and non-albicans Candida spp. are becoming more prevalent. Acquired resistance to antifungal agents has been documented in several reports. The aim of our study was to assess the epidemiology and antifungal susceptibility of Candida isolates from BSI at our institute. The incidence of Candida BSI increased during the first four years of our investigation, from 1.7 to 3.5 episodes / 10 000 admissions, then dropped to 2.66 episodes / 10 000 admissions in the last year. The most frequently isolated species was C. albicans (63%), followed by C. glabrata (13%), C. parapsilosis (10.2%), C. tropicalis (9.3%), and C. krusei (3.7%). One isolate each of C. kefyr, C. fabianii and C. inconspicua were detected. The percentage of C. albicans remained stable throughout the study period. The most frequent risk factors of Candida BSI in our patient population were intensive care treatment (60.4%), abdominal surgery (52.5%), and solid malignancy (30.7%). All isolates were wild-type organisms, no acquired antifungal resistance was detected

A fekélybetegség és a stressz

The discovery that Helicobacter pylori infection is the major cause of peptic ulcer disease revolutionised our views on the etiology and treatment of the disease. This discovery has tempted many experts to conclude that psychological factors and, specifically, stress are unimportant. However, Helicobacter pylori infection alone does not explain fully the incidence and prevalence of peptic ulcer disease. It has been demonstrated that stress can cause peptic ulcer disease even in the absence of Helicobacter pylori infection, supporting a multicausal model of peptic ulcer etiology. Psychological stress among other risk factors can function as a cofactor with Helicobacter pylori infection. Orv. Hetil., 2015, 156(35), 1426-1429

ANTIBIOTIC SUSCEPTIBILITY OF SULFAMETHOXAZOLE-TRIMETHOPRIM RESISTANT STENOTROPHOMONAS MALTOPHILIA STRAINS ISOLATED AT A TERTIARY CARE CENTRE IN HUNGARY

Sulfamethoxazole-trimethoprim (SXT) is the drug-of-choice in Stenotrophomonas maltophilia caused infections. There has been an increase in resistance to SXT of S. maltophilia over recent years. In this study 30 S. maltophilia clinical isolates resistant to SXT were investigated. Antibiotic susceptibilities for ciprofloxacin, moxifloxacin, levofloxacin, doxycycline, tigecycline, ceftazidime, colistin and chloramphenicol were determined by broth microdilution method. None of the strains were susceptible to ciprofloxacin, tigecycline, ceftazidime or colistin. Only 37% of the isolates were susceptible to levofloxacin or moxifloxacin. Two isolates resistant to all tested antibiotic agents and two others susceptible only to doxycycline were further investigated: susceptibility for combinations of antibiotics was analyzed by checkerboard technique. According to the fractional inhibitory concentration indices calculated, moxifloxacin plus ceftazidime combination was found to be synergistic in each case. Genetic testing revealed the predominance of sul1 gene. Our study concluded that the range of effective antibiotic agents is even more limited in infections caused by SXT-resistant S. maltophilia. In these cases, in vitro synergistic antibiotic combinations could be potential therapeutic options

Gaia Data Release 2. Validating the classification of RR Lyrae and Cepheid variables with the Kepler and K2 missions

Context. The second data release of the Gaia mission (DR2) includes an advance catalogue of variable stars. The classifications of these stars are based on sparse photometry from the first 22 months of the mission. Aims: We set out to investigate the purity and completeness of the all-sky Gaia classification results with the help of the continuous light curves of the observed targets from the Kepler and K2 missions, focusing specifically on RR Lyrae and Cepheid pulsators, outside the Galactic bulge region. Methods: We cross-matched the Gaia identifications with the observations collected by the Kepler space telescope. We inspected the light curves visually, then calculated the relative Fourier coefficients and period ratios for the single- and double-mode K2 RR Lyrae stars to further classify them. Results: We identified 1443 and 41 stars classified as RR Lyrae or Cepheid variables in Gaia DR2 in the targeted observations of the two missions and 263 more RR Lyre targets in the full-frame images (FFI) of the original mission. We provide the cross-match of these sources. We conclude that the RR Lyrae catalogue has a completeness between 70-78%, and provide a purity estimate of between 92 and 98% (targeted observations) with lower limits of 75% (FFI stars) and 51% (K2 worst- case scenario). The low number of Cepheids prevents us from drawing detailed conclusions, but the purity of the DR2 sample is estimated to be about 66%. Full Tables A1, A4, and A5 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz- bin/qcat?J/A+A/620/A12

Gastritisek es gastropathiak.

Alterations of the stomach mucosa in response to different adverse effects result in various morphological and clinical symptoms. Gastric mucosa alterations can be classified on the bases of diverse viewpoints. It makes this overview difficult, that identical toxic effects may cause different mucosal changes and different toxic agents may produce similar mucosal appearance. The more accurate understanding of the pathological processes which develop in the stomach mucosa needs reconsideration. The authors make an attempt to define gastritis and gastropathy in order to classify and present their features. Gastritis is a histological definition indicating mucosal inflammation. Acute gastritis is caused by infections. The two most important forms of chronic gastritis are metaplastic atrophic gastritis with an autoimmune origin and Helicobacter pylori inflammation. Gastropathy is the name of different structural alterations of the mucosa. Its most important feature is the paucity of inflammatory signs. Gastropathies can be divided into 4 categories based on the nature of the underlying pathological effect, on its morphological appearance and the way of the development. Differential diagnosis is an important pathological and clinical task because different treatment methods and prognosis. Orv. Hetil., 2014, 155(2), 43-61

Does Staphylococcus saprophyticus cause acute cystitis only in young females, or is there more to the story? A one-year comprehensive study done in Budapest, Hungary

Staphylococcus saprophyticus is a well-known urinary pathogen in acute cystitis in young females. We completed a retrospective overview of the distribution of urinary tract infections (UTIs) occurring in 2014, at Semmelweis University hospitals and at Heim Pál Children's Hospital. Six age-groups (ages 0-100) were examined, with the frequency of S. saprophyticus in females being: 0.1% (0-4), 0.7%, (5-15), 7.4% (16-24), 1.2% (25-39), 0.4% (40-59) and 0.1% (60-100), and S. saprophyticus being the 3rd most common pathogen in females aged 16-24. In males, S. saprophyticus was only isolated from those aged 5-15. Seasonal distribution of UTIs caused by S. saprophyticus showed that most infections occurred during the months of January, June, August and November. Antibiotic-resistance rates of amoxicillin, clindamycin, doxycycline, erythromycin, gentamicin and sulfamethoxazole- trimethoprim varied as follows: 0.9%, 32.7%, 19.6%, 34.6%, 0.9% and 0.9%, respectively. Thirty randomly selected samples were analysed by pulsed-field gelelectrophoresis, and 28 different genotypes were identified. S. saprophyticus is involved in the pathogenesis of acute cystitis not only in young females, but also in other age-groups, and in young males as well. We did not find any significant seasonal occurrence in S. saprophyticus-caused UTIs. The infective strains were genetically diverse. Antibiotic-resistance does not pose any issue as of yet. © 2016 Akadémiai Kiadó, Budapest

Contribution to the hungarian caddisfly (Trichoptera) fauna, based on the nationwide surveys in 2007

In the frame of countrywide level projects altogether 77 Trichoptera species were collected in Hungary in 2007. This is 37 percent of the Hungarian Trichoptera fauna. The collected species belong to 11 families. There are 7 identified species with the greatest faunistical importance: Silo nigricornis, Silo piceus, Anabolia brevipennis, Phryganea bipunctata, Ylodes simulans and Cheumatopsyche lepida