Protons Interaction with Nomex Target: Secondary Radiation from a Monte Carlo Simulation with Geant4

The study of suitable materials to shield astronauts from Galactic Cosmic Rays (GCR) is a topic of fundamental importance. The choice of the material must take into account both the secondary radiation produced by the interaction between primary radiation and material and its shielding ability. The physics case presented here deals with the interaction of a proton beam with a Nomex shield, namely, a target material with a mass thickness of 20 g cm−2. The study was conducted with the simulation code DOSE based on the well-known simulation package Geant4. This article shows the properties of secondary radiations produced in the target by the interaction of a proton beam in an energy range characterizing the GCR spectrum. We observed the production of ions of masses and charges lower than the chemical elements that make up Nomex, and also a significant production of neutrons, protons, and particles

Arachnoiditis ossificans, isthmic spondylolisthesis and pseudomeningocele. A rare clinical scenario

The combination of arachnoiditis ossificans, isthmic spondylolisthesis and calcific pseudomeningocele is an extremely unusual condition. In the current literature, there is no previous report of this intricate clinical scenario, and therefore there are no clear indications on the best treatment. In the reported surgical case, the excision of calcific pseudomeningocele, L4 bilateral laminectomy and foraminotomy and posterolateral fusion were performed. L4L5 interbody fusion was aborted for impossibility of neural elements mobilization and a consequent intraoperative dural tear. The aims of the adopted surgical procedure are the decompression of neural elements and the stability due to bone fusion

Original Surgical Treatment and Long-term Follow-up for Chronic Inflammatory Demyelinating Polyradiculoneuropathy Causing a Compressive Cervical Myelopathy: Review of the Literature

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a chronic relapsing disease of unknown aetiology. The diagnosis of this disease is still very complicated. The treatment is medical but, in some cases, a surgical decompression might be required. In rare cases it develops a radicular hypertrophy that can cause a cervical myelopathy; this pathology should be put in differential diagnosis with neurofibromatosis 1 and Charcot-Marie-Tooth (CMT) syndromes. The cases of CIDP cervical myelopathy reported in the literature are rare and even more rarely a surgical decompression was described. Here we report a first and unique case of CIDP cervical myelopathy treated with an open-door laminoplasty technique with 10-year postoperative follow-up (FU). The surgical decompression revealed to be effective in stopping the progression of myelopathy without destabilizing the spine. The patient that before surgery presented a severe tetraparesis could return to walk and gain back his self-care autonomy. At 10-year FU he did not complain of neck pain and did not develop a cervical kyphosis. In case of cervical myelopathy caused by radicular hypertrophy, CIDP should be kept in mind in the differential diagnosis and an open-door laminoplasty is indicated to stop myelopathy progression

Cervical Inclination Angle: Normative Values in an Adult Multiethnic Asymptomatic Population

Objective The role of the craniocervical complex in spinal sagittal alignment has rarely been analyzed but it may play a fundamental role in postoperative mechanical complications. The aim of the study is to analyze the normative value of the cervical inclination angle (CIA) in an adult asymptomatic multiethnic population. Methods Standing full-spine EOS of adult asymptomatic volunteers from 5 different countries were analyzed. The CIA was analyzed globally and then in each decade of life. Different ethnicities were compared. Comparisons between different groups was performed using a t-test and statistical significance was considered with a p-value < 0.05. Results EOS of 468 volunteers were analyzed. The global mean CIA was 80.2° with a maximum difference of 9° between T1 and T12 (p < 0.001). The CIA remains constant until 60 years old then decreases significantly passing from a mean value before 20 years old of 82.25° to 73.65° after 70 years old. A statistically significant difference was found between the Arabics and other ethnicities with the formers having an inferior CIA: this was related to a mean older age (p < 0.05) and higher body mass index (p < 0.05) in the Arabics. Conclusion The CIA remains constant until 60 years old and then reduces slightly but never under 70°. This angle is helpful to evaluate the lever arm at the upper instrumented vertebra after an adult spinal deformity surgery and could predict the occurrence of a proximal junctional kyphosis when its value is lower than normal. Further clinical studies must confirm this theory

Influenza vaccination coverage among medical residents: An Italian multicenter survey

Although influenza vaccination is recognized to be safe and effective, recent studies have confirmed that immunization coverage among health care workers remain generally low, especially among medical residents (MRs). Aim of the present multicenter study was to investigate attitudes and determinants associated with acceptance of influenza vaccination among Italian MRs. A survey was performed in 2012 on MRs attending post-graduate schools of 18 Italian Universities. Each participant was interviewed via an anonymous, self-administered, web-based questionnaire including questions on attitudes regarding influenza vaccination. A total of 2506 MRs were recruited in the survey and 299 (11.9%) of these stated they had accepted influenza vaccination in 2011-2012 season. Vaccinated MRs were older (P = 0.006), working in clinical settings (P = 0.048), and vaccinated in the 2 previous seasons (P < 0.001 in both seasons). Moreover, MRs who had recommended influenza vaccination to their patients were significantly more compliant with influenza vaccination uptake in 2011-2012 season (P < 0.001). "To avoid spreading influenza among patients" was recognized as the main reason for accepting vaccination by less than 15% of vaccinated MRs. Italian MRs seem to have a very low compliance with influenza vaccination and they seem to accept influenza vaccination as a habit that is unrelated to professional and ethical responsibility. Otherwise, residents who refuse vaccination in the previous seasons usually maintain their behaviors. Promoting correct attitudes and good practice in order to improve the influenza immunization rates of MRs could represent a decisive goal for increasing immunization coverage among health care workers of the future. © 2014 Landes Bioscience

Validation of electromagnetic and hadronic physical processes in the interaction of a proton beam with matter: A Solar Particle Events case study with an Al slab

n the study of the effectiveness of shielding materials against radiations, one of the main steps concerns with the validation of models describing the interaction processes of the radiation of interest with the material chosen for the shielding. This paper shows the results of the validation of electromagnetic and hadronic processes with the aim to contribute to the study of protection for astronauts against the radiations due to the Solar Particle Events, in particular to the selection of the optimal material for radiation shielding. The physics case deals with the interaction of a proton beam with an aluminum slab about 20 g/cm2 thick. Two specific applications, STP and DOSE, were developed by using Geant4 package. STP computes the radiations produced in the interaction and their stopping power; DOSE computes the absorbed dose from the stopping power calculated by STP. The validation process was performed in two steps. In the first one, the output of the STP code is compared to data available on NIST database; in the second one, the absorbed dose computed with DOSE is compared to the dose gathered during an experiment performed at the NASA Space Radiation Laboratory involving the bombardment of an aluminum slab with a 1 GeV proton beam. The computing model has allowed us to correlate the size of the impinging beam profile to the dose measured before and after an Al slab. The sharp increase of the dose in the position right after the slab might be due to the stochastic nature of the trajectories of charged ions in matter which makes the radiation to emerge with non-zero transverse linear momentum. From the case examined here, we conclude that aluminum is not an efficient material for Solar Particle Event shielding

Dosimetry in Space: The shielding effectiveness for the radioprotection of astronauts against 1 GeV protons

The study of materials suitable for radiation protection of astronauts in space missions is always a topic of fundamental importance. The main aim of any radiation protection program in space is to minimize the crew’s exposure to ionizing radiation. This work concerns the effectiveness of shielding materials against radiation in space conditions, in particular for the Galactic Cosmic Radiation. The study was conducted by developing a simulation tool based on the Geant4 framework. The physics case reported here deals with the interaction of a 1 GeV proton beam (protons represent about 87% of the GCR flux with the energy spectrum peak around 1 GeV) with a target added with boric acid or gadolinium (Gd) to deplete neutron escaping. Charge, mass and energy distributions of secondary particles generated by the interaction are computed on the basis of different interaction models. It is found that the particles escaping the shielding material and reaching an ionization chamber located in the opposite side of the shield are still mainly protons and neutrons. The added boric acid acts as an effective neutron mitigating material. However, the average dose does not change effectively because of the additional production of alpha particles from the reaction 10B(n, α)

Radioprotection for Astronauts’ Missions: Numerical Results on the Nomex Shielding Effectiveness

Space missions with humans expose the crews to ionizing radiation, mainly due to the galactic cosmic radiation (GCR). All radiation protection programs in space aim to minimize crews’ exposure to radiation. The radiation protection of astronauts can be achieved through the use of shields. The shields could serve as a suit to reduce GCR exposure and, in an emergency, as a radiation shelter to perform necessary interventions outside the space habitat in case of a solar proton event (SPE). A space radiation shielding that is suitable for exploration during space missions requires particular features and a proper knowledge of the radiation type. This study shows the results of numerical simulations performed with the Geant4 toolkit-based code DOSE. Calculations to evaluate the performance of Nomex, an aramidic fiber with high mechanical resistance, in terms of dose reduction to crews, were performed considering the interaction between protons with an energy spectrum ranging from 50 to 1100 MeV and a target slab of 20 g/cm2. This paper shows the properties of secondary products obtained as a result of the interaction between space radiation and a Nomex target and the properties of the secondary particles that come out the shield. The results of this study show that Nomex can be considered a good shield candidate material in terms of dose reductions. We also note that the secondary particles that provide the greatest contribution to the dose are protons, neutrons and, in a very small percentage, α-particles and Li ions