Investigating the Distinctions in Physical Well-being and Life Satisfaction between Women with Hypothyroidism and Healthy Individuals: A Focus on Rehabilitation School Attendees

Introduction: Hypothyroidism, characterized by an underactive thyroid, is a prevalent condition often accompanied by metabolic changes and goiter. Despite successful treatment, previous research suggests that the quality of life for many patients may be reduced. This study aims to investigate the quality of life in women with hypothyroidism, specifically those treated with levothyroxine, by comparing them to a control group. Materials and Methods: A case-control study involving 61 women aged 18 to 65 with hypothyroidism treated with levothyroxine was conducted. The World Health Organization Quality of Life-26 questionnaire (WHO/QOL-BREF) was used to assess health-related quality of life (HRQOL). The collected data from the WHO/QOL-BREF questionnaires were compared between the patient group and a healthy control group. Serum T4 and TSH levels were also measured in both groups. Results: The average WHO/QOL-BREF score for the patient group was 84.7±10.9, while the healthy control group scored 88.3±12.1. Although there was no significant difference in overall HRQOL, significant differences were observed between the two groups in the physical health (13.75±2.54 for patients and 14.9±2.1 for healthy individuals) and psychological health domains (11.84±2.69 for patients and 13.2±2.3 for healthy individuals). No significant differences were found in the social and environmental health domains (social: patients 12.51±3.15, healthy individuals 12.1±3.4; environmental: patients 13.62±1.75, healthy individuals 13.3±2.2) (P-value=0.74). Conclusion: In this study, significant differences were observed only in the physical and psychological health domains of women with treated hypothyroidism, with their average scores being lower than those of healthy individuals. However, no significant differences were found in the social and environmental health domains between the two groups

Hereditary Sensory and Autonomic Neuropathy Type IV in 9 Year Old Boy: A Case Report

How to Cite This Article: Azadvari M, Emami Razavi SZ, Kazemi Sh. Hereditary Sensory and Autonomic Neuropathy Type IV in 9 Year Old Boy: A Case Report. Iran J Child Neurol. Spring 2016; 10(2):83-85.AbstractObjectiveThe Hereditary Sensory and Autonomic neuropathy (HSAN) is a rare group of neuropathies that affects the Sensory and Autonomic nervous system. The patients do not have the ability of sensing different sensations such as pain and temperature, which tends to lead to different injuries. In addition, due to autonomic involvement, the patients suffer from fluctuation in body temperature periodically and lack of precipitation. HSAN is divided into 5 types according to the age of onset, clinical features, and inheritance. Our case was a 9-yr old boy from cousin parents. He had some developmental delay and history of recurrent fever and convulsion in the first year of his life. Gradually, other symptoms added to patient’ feature such as multiple painless skin ulcers, tooth loss, destruction of toes and fingers. In electrodiagnostic study, we found decreased amplitude of sensory nerves, while the other studies were normal. Laboratory test and imaging studies were also normal. All clinical and paraclinical findings were in favor of HSAN type IV. There is no cure for such patients; as a result, these patients and their families need receiving appropriate education and timely rehabilitation services.References Labib S, AdnaneBerdai M, Abourazzak S, Hida M, Harandou M. Congenitalinsensitivity to pain with anhydrosis: report of a family case. Pan Afr Med J 2011;9:33.Amato A, Dumitru D. Hereditary Neuropathies. In: Dumitru D, Amato A, Zwarts M, Electrodiagnostic Medicine. 2nd ed. Philadelphia; Hanely&Belfus 2002: 911-914.Yuan J, Matsuura E, Higuchi Y, Hashiguchi A, Nakamura T, Nozuma S, Sakiyama Y, Yoshimura A, Izumo S, Takashima H. Hereditary sensory and autonomic neuropathy type IID caused by an SCN9A mutation. Neurology 2013 Apr 30;80(18):1641-9.Edvardson S, Cinnamon Y, Jalas C, et al. Hereditary sensory autonomic neuropathy caused by a mutation in dystonin. Ann Neurol 2012;71:569–572.Verhoeven K, Timmerman V, Mauko B, Pieber TR, De Jonghe P, Auer-GrumbachM.Recent advances in hereditary sensory and autonomic neuropathies. CurrOpinNeurol 2006;19(5):474-80.Axelrod FB, Gold-von Simson G. Hereditary sensory and autonomic neuropathies: types II, III, and IV. Orphanet J Rare Dis 2007;2:39. Review.Sany-Soo Lee, Sung-H Lee, Seol-H Han. Terminal changes in hereditary sensory and autonomic neuropathy. A long term follow-up of a sporadic case. Clinical Neurology and Neurosurgery 2003;105(3): 175-179.Kim W, Guinot A, Marleix S, Chapuis M, Fraisse B, Violas P. Hereditary sensory and autonomic neuropathy type IV and orthopaedic complications. OrthopTraumatolSurg Res 2013;99(7):881-5.Safari A, Khaledi AA, &Vojdani M. Congenital Insensitivity to Pain withAnhidrosis (CIPA): A Case Report. Iran Red Crescent Med J 2011;13(2):134-8.Gharagozlou M, Zandieh F, Tabatabaei P,&ZamaniGh. Congenital Sensory Neuropathy as a differential diagnosis for phagocytic Immunodeficiency. Iran J Allergy Asthma 2006; 5(1): 35-37.Baghdadi T ,Sadeghifar A , Mortazavi S.M.J, &Espandar R . Indifference to pain syndrome in a twelve-year-old boy (case report). Tehran Univ Med J 2007; 65 (4) :87-91

Chronic Back Pain Diagnosed as Giant Osteoid Osteoma of the Thoracic Vertebra: A Case Report

Introduction: Diagnosing an osteoid osteoma as a benign tumor can be challenging owing to its different presentation patterns, ambiguous radiological findings and unusual sites of involvement. The present case report involves a 30-year-old female patient with a large osteoid osteoma of the thoracic vertebrae as an uncommon site of its presentation. Case Presentation: The patient presented with a one-year history of progressive right-sided upper back and interscapular pains. She was identified as a candidate for surgery using the whole body bone scan and a multiple detector computed tomography (MDCT) scan. A large 25-mm osteoid osteoma of the lamina of the third thoracic vertebra (T3) was also diagnosed through histopathology. Conclusion: As a potential cause of persistent back pain in young adults, an osteoid osteoma may be easily missed by routine radiographs. The CT scan is an effective tool in the investigation of the size and location of this tumor. Surgical excision can also be used for treating spinal lesions

Chronic Back Pain Diagnosed as Giant Osteoid Osteoma of the Thoracic Vertebra: A Case Report

Introduction: Diagnosing an osteoid osteoma as a benign tumor can be challenging owing to its different presentation patterns, ambiguous radiological findings and unusual sites of involvement. The present case report involves a 30-year-old female patient with a large osteoid osteoma of the thoracic vertebrae as an uncommon site of its presentation. Case Presentation: The patient presented with a one-year history of progressive right-sided upper back and interscapular pains. She was identified as a candidate for surgery using the whole body bone scan and a multiple detector computed tomography (MDCT) scan. A large 25-mm osteoid osteoma of the lamina of the third thoracic vertebra (T3) was also diagnosed through histopathology. Conclusion: As a potential cause of persistent back pain in young adults, an osteoid osteoma may be easily missed by routine radiographs. The CT scan is an effective tool in the investigation of the size and location of this tumor. Surgical excision can also be used for treating spinal lesions

Mapping the Scientific Outputs in the Field of Physiotherapy: A Co-Word Analysis

Introduction: Evaluation and analysis of scientific outputs and between-keywords relationship could provide the investigators with useful information. The aim of this study was mapping of scientific outputs in the field of physiotherapy, with applying the co-word analysis in the ISI Web of Science database. Methods and Materials: This study was a scientometric approach using the co-word and network analyses in the field of physiotherapy. Published papers from 2000 to 2018 were reviewed and the results were analyzed by Excel, UCINET, Netdraw and VOSviewer. Results: Results showed an increasing trend of scientific outputs in the field of physiotherapy. United States of America (USA) achieved the first rank (7400 documents) followed by England and Australia. Among the Middle East countries, Turkish with 981 documents achieved the first rank while Iran with 235 documents owned the third rank. Regarding the frequently used subjects, the most scientific outputs in the field of physiotherapy were shared with Physical medicine and Rehabilitation, Orthopedic, Neuroscience, Sport medicine, Internal medicine, Surgery, Rheumatology, Health medicine, Pediatrics, and Pulmonology. Results revealed rehabilitation, physiotherapy, exercise, physical therapy, and management based on degree centrality and disability, therapy, physiotherapy, outcome based on both of the betweenness and closeness centrality had the most impact on the network. Conclusion: Regarding the trend of scientific outputs, physiotherapy is most related to orthopedic, neuroscience, and pediatric. Moreover, scientific interaction to increase scientific outputs in Iran and other Middle East countries seems to be essential. Additionally, mapping of co-word analyses could provide the policy makers with information regarding the research, key words, and the relationship between key words in the field of physiotherapy. Therefore, they can plan essential and appropriate programs to improve both the quality and quantity of the scientific outputs in this field

Social factors associated with infants’ mortality

One of the important health indices showing health status of a society is health index of mortality rate of children < 1 year. There are many negative parameters weakening potentiality of children in growth and development of which some can be categorized as social factors. This research has tried to investigate some factors as education level, parents’ jobs, maternal care, the times of child care, breast feeding and < 1 year children mortality. This is a descriptive comparative retrospective study in which there were 121 less then 1 year children (dead and live) referring to Isfahan health centers selected with all including criteria. The data were collected by questionnaires and categorized into two groups, to be investigated and compared. Content validity and standardized fixed forms were used for questionnaire validity and reliability respectively. The data were analyzed by descriptive inferential statistics (X2, T-test) . The findings showed that there was a significant association between parents’ education, fathers’ jobs. mothers’ jobs, manner of breast feeding, the times of child care, maternal care and mortality of children < 1 year. Regarding the results, it seems that government, organization, and authorities concerning health strategies as well as health provider staffs play a major role in prediction and control of social factors affecting infants’ mortality. These roles can be in forms of education, socio economic and cultural status promoting plans among men and women as well as enhancement of public knowledge