2,063 research outputs found

    1964 Grain Sorghum Performance Trials

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    The 1964 Grain Sorghum Performance Trials were conducted at ten locations in South Dakota. Varieties presently grown by farmers, new varieties not yet widely used and new strains being considered for release were eligible for entry in the 1964 trials. The trials were under the supervision of the Crop Performance Testing Activity of the Agricultural Experiment Station. Grain yields, test weights and other agronomic data are reported

    Breast Cancer in the Personal Genomics Era

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    Breast cancer is a heterogeneous disease with a complex etiology that develops from different cellular lineages, progresses along multiple molecular pathways, and demonstrates wide variability in response to treatment. The “standard of care” approach to breast cancer treatment in which all patients receive similar interventions is rapidly being replaced by personalized medicine, based on molecular characteristics of individual patients. Both inherited and somatic genomic variation is providing useful information for customizing treatment regimens for breast cancer to maximize efficacy and minimize adverse side effects. In this article, we review (1) hereditary breast cancer and current use of inherited susceptibility genes in patient management; (2) the potential of newly-identified breast cancer-susceptibility variants for improving risk assessment; (3) advantages and disadvantages of direct-to-consumer testing; (4) molecular characterization of sporadic breast cancer through immunohistochemistry and gene expression profiling and opportunities for personalized prognostics; and (5) pharmacogenomic influences on the effectiveness of current breast cancer treatments. Molecular genomics has the potential to revolutionize clinical practice and improve the lives of women with breast cancer

    The Bolocam Galactic Plane Survey. XII. Distance Catalog Expansion Using Kinematic Isolation of Dense Molecular Cloud Structures With 13CO(1-0)

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    We present an expanded distance catalog for 1,710 molecular cloud structures identified in the Bolocam Galactic Plane Survey (BGPS) version 2, representing a nearly threefold increase over the previous BGPS distance catalog. We additionally present a new method for incorporating extant data sets into our Bayesian distance probability density function (DPDF) methodology. To augment the dense-gas tracers (e.g., HCO+(3-2), NH3(1,1)) used to derive line-of-sight velocities for kinematic distances, we utilize the Galactic Ring Survey 13CO(1-0) data to morphologically extract velocities for BGPS sources. The outline of a BGPS source is used to select a region of the GRS 13CO data, along with a reference region to subtract enveloping diffuse emission, to produce a line profile of 13CO matched to the BGPS source. For objects with a HCO+(3-2) velocity, \approx 95% of the new 13CO(1-0) velocities agree with that of the dense gas. A new prior DPDF for kinematic distance ambiguity (KDA) resolution, based on a validated formalism for associating molecular cloud structures with known objects from the literature, is presented. We demonstrate this prior using catalogs of masers with trigonometric parallaxes and HII regions with robust KDA resolutions. The distance catalog presented here contains well-constrained distance estimates for 20% of BGPS V2 sources, with typical distance uncertainties \lesssim 0.5 kpc. Approximately 75% of the well-constrained sources lie within 6 kpc of the Sun, concentrated in the Scutum-Centarus arm. Galactocentric positions of objects additionally trace out portions of the Sagittarius, Perseus, and Outer arms in the first and second Galactic quadrants, and we also find evidence for significant regions of interarm dense gas.Comment: 28 pages, 19 figures. Accepted for publication in ApJ. Distance-Omnibus code available at https://github.com/BGPS/distance-omnibu

    The Bolocam Galactic Plane Survey. XIII. Physical Properties and Mass Functions of Dense Molecular Cloud Structures

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    We use the distance probability density function (DPDF) formalism of Ellsworth-Bowers et al. (2013, 2015) to derive physical properties for the collection of 1,710 Bolocam Galactic Plane Survey (BGPS) version 2 sources with well-constrained distance estimates. To account for Malmquist bias, we estimate that the present sample of BGPS sources is 90% complete above 400 MM_\odot and 50% complete above 70 MM_\odot. The mass distributions for the entire sample and astrophysically motivated subsets are generally fitted well by a lognormal function, with approximately power-law distributions at high mass. Power-law behavior emerges more clearly when the sample population is narrowed in heliocentric distance (power-law index α=2.0±0.1\alpha = 2.0\pm0.1 for sources nearer than 6.5 kpc and α=1.9±0.1\alpha = 1.9\pm0.1 for objects between 2 kpc and 10 kpc). The high-mass power-law indices are generally 1.85α2.051.85 \leq \alpha \leq 2.05 for various subsamples of sources, intermediate between that of giant molecular clouds and the stellar initial mass function. The fit to the entire sample yields a high-mass power-law α^=1.940.10+0.34\hat{\alpha} = 1.94_{-0.10}^{+0.34}. Physical properties of BGPS sources are consistent with large molecular cloud clumps or small molecular clouds, but the fractal nature of the dense interstellar medium makes difficult the mapping of observational categories to the dominant physical processes driving the observed structure. The face-on map of the Galactic disk's mass surface density based on BGPS dense molecular cloud structures reveals the high-mass star-forming regions W43, W49, and W51 as prominent mass concentrations in the first quadrant. Furthermore, we present a 0.25-kpc resolution map of the dense gas mass fraction across the Galactic disk that peaks around 5%.Comment: Accepted for publication in ApJ; 32 pages, 21 figure

    The NASA Micro Pulse Lidar Network (MPLNET): Introduction of the New Version 3 Release

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    The NASA Micro-Pulse Lidar Network (MPLNET) is a global federated network of polarized Micro-Pulse Lidar (MPL) systems running continuously. MPLNET began in 2000, and there have been over 70 sites deployed worldwide, with 24 sites currently active and a few more planned over the next year. Seven of the long-term sites have 10+ years of data, and many more have 5+ years. Most sites are co-located with AERONET providing joint data on column and vertically resolved aerosol and cloud information. This presentation will introduce our new Version 3 MPLNET data. All sites in the network now feature eye-safe polarized backscatter MPL instruments, providing information on attenuated backscatter and particle shape. In addition to change with our signal data, we have an enhanced cloud product suite, a new PBL height product, and inclusion of the new AERONET lunar aerosol optical depth into MPLNET aerosol retrievals. A new quality flag process will be used to better describe all data products. Finally, a new data portal will provide near-real-time (NRT) access to all data products, including new quality assured NRT L1.5 products. Custom products developed for model specific applications will also be provided

    The Bolocam Galactic Plane Survey. XIV. Physical Properties of Massive Starless and Star Forming Clumps

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    We sort 46834683 molecular clouds between 10<<6510^\circ< \ell <65^\circ from the Bolocam Galactic Plane Survey based on observational diagnostics of star formation activity: compact 7070 μm\mu{\rm m} sources, mid-IR color-selected YSOs, H2O{\rm H_2O} and CH3OH{\rm CH_3OH} masers, and UCHII regions. We also present a combined NH3{\rm NH_3}-derived gas kinetic temperature and H2O{\rm H_2O} maser catalog for 17881788 clumps from our own GBT 100m observations and from the literature. We identify a subsample of 22232223 (47.5%47.5\%) starless clump candidates, the largest and most robust sample identified from a blind survey to date. Distributions of flux density, flux concentration, solid angle, kinetic temperature, column density, radius, and mass show strong (>1>1 dex) progressions when sorted by star formation indicator. The median starless clump candidate is marginally sub-virial (α0.7\alpha \sim 0.7) with >75%>75\% of clumps with known distance being gravitationally bound (α<2\alpha < 2). These samples show a statistically significant increase in the median clump mass of ΔM170370\Delta M \sim 170-370 M_\odot from the starless candidates to clumps associated with protostars. This trend could be due to (i) mass growth of the clumps at M˙200440\dot{M}\sim200-440 Msun Myr1^{-1} for an average free-fall 0.80.8 Myr time-scale, (ii) a systematic factor of two increase in dust opacity from starless to protostellar phases, (iii) and/or a variation in the ratio of starless to protostellar clump lifetime that scales as M0.4\sim M^{-0.4}. By comparing to the observed number of CH3OH{\rm CH_3OH} maser containing clumps we estimate the phase-lifetime of massive (M>103M>10^3 M_\odot) starless clumps to be 0.37±0.08 Myr (M/103 M)10.37 \pm 0.08 \ {\rm Myr} \ (M/10^3 \ {\rm M}_\odot)^{-1}; the majority (M<450M<450 M_\odot) have phase-lifetimes longer than their average free-fall time.Comment: Accepted for publication in ApJ; 33 pages; 22 figures; 7 table

    Remote sensing data from CLARET: A prototype CART data set

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    The data set containing radiation, meteorological , and cloud sensor observations is documented. It was prepared for use by the Department of Energy's Atmospheric Radiation Measurement (ARM) Program and other interested scientists. These data are a precursor of the types of data that ARM Cloud And Radiation Testbed (CART) sites will provide. The data are from the Cloud Lidar And Radar Exploratory Test (CLARET) conducted by the Wave Propagation Laboratory during autumn 1989 in the Denver-Boulder area of Colorado primarily for the purpose of developing new cloud-sensing techniques on cirrus. After becoming aware of the experiment, ARM scientists requested archival of subsets of the data to assist in the developing ARM program. Five CLARET cases were selected: two with cirrus, one with stratus, one with mixed-phase clouds, and one with clear skies. Satellite data from the stratus case and one cirrus case were analyzed for statistics on cloud cover and top height. The main body of the selected data are available on diskette from the Wave Propagation Laboratory or Los Alamos National Laboratory

    National Seismic System Science Plan

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    Recent developments in digital communication and seismometry are allowing seismologists to propose revolutionary new ways to reduce vulnerability from earthquakes, volcanoes, and tsunamis, and to better understand these phenomena as well as the basic structure and dynamics of the Earth. This document provides a brief description of some of the critical new problems that can be addressed using modem digital seismic networks. It also provides an overview of existing seismic networks and suggests ways to integrate these together into a National Seismic System. A National Seismic System will consist of a number of interconnected regional networks (such as southern California, central and northern California, northeastern United States, northwestern United States, and so on) that are jointly operated by Federal, State, and private seismological research institutions. Regional networks will provide vital information concerning the hazards of specific regions. Parts of these networks will be linked to provide uniform rapid response on a national level (the National Seismic Network). A National Seismic System promises to significantly reduce societal risk to earthquake losses and to open new areas of fundamental basic research. The following is a list of some of the uses of a National Seismic System

    The Algorithm Theoretical Basis Document for the GLAS Atmospheric Data Products

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    The purpose of this document is to present a detailed description of the algorithm theoretical basis for each of the GLAS data products. This will be the final version of this document. The algorithms were initially designed and written based on the authors prior experience with high altitude lidar data on systems such as the Cloud and Aerosol Lidar System (CALS) and the Cloud Physics Lidar (CPL), both of which fly on the NASA ER-2 high altitude aircraft. These lidar systems have been employed in many field experiments around the world and algorithms have been developed to analyze these data for a number of atmospheric parameters. CALS data have been analyzed for cloud top height, thin cloud optical depth, cirrus cloud emittance (Spinhirne and Hart, 1990) and boundary layer depth (Palm and Spinhirne, 1987, 1998). The successor to CALS, the CPL, has also been extensively deployed in field missions since 2000 including the validation of GLAS and CALIPSO. The CALS and early CPL data sets also served as the basis for the construction of simulated GLAS data sets which were then used to develop and test the GLAS analysis algorithms
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