59 research outputs found

    Australian marsupials

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    6 p. ; 24 cm.Includes bibliographical references (p. 6).Planigale ingrami brunneus -- Parantechinus apicalis -- The type of Dasyurus gracilis -- The skull of the pig-footed bandicoot, Chaeropus ecaudatus -- The deciduous premolars of Macrotis lagotis -- Petaurus australis australis -- Protemnodon irma -- Onychogalea fraenata

    Convalescent troponin and cardiovascular death following acute coronary syndrome

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    Objectives: High-sensitivity cardiac troponin testing is used in the diagnosis of acute coronary syndromes but its role during convalescence is unknown. We investigated the long-term prognostic significance of serial convalescent high-sensitivity cardiac troponin concentrations following acute coronary syndrome. Methods: In a prospective multicentre observational cohort study of 2140 patients with acute coronary syndrome, cardiac troponin I concentrations were measured in 1776 patients at 4 and 12 months following the index event. Patients were stratified into three groups according to the troponin concentration at 4 months using the 99th centile (women>16 ng/L, men>34 ng/L) and median concentration of those within the reference range. The primary outcome was cardiovascular death. Results: Troponin concentrations at 4 months were measurable in 99.0% (1759/1776) of patients (67±12 years, 72% male), and were ≤5 ng/L (median) and >99th centile in 44.8% (795) and 9.3% (166), respectively. There were 202 (11.4%) cardiovascular deaths after a median of 4.8 years. After adjusting for the Global Registry of Acute Coronary Events score, troponin remained an independent predictor of cardiovascular death (HR 1.4, 95% CI 1.3 to 1.5 per doubling) with the highest risk observed in those with increasing concentrations at 12 months. Patients with 4-month troponin concentrations >99th centile were at increased risk of cardiovascular death compared with those ≤5 ng/L (29.5% (49/166) vs 4.3% (34/795); adjusted HR 4.9, 95% CI 3.8 to 23.7). Conclusions: Convalescent cardiac troponin concentrations predict long-term cardiovascular death following acute coronary syndrome. Recognising this risk by monitoring troponin may improve targeting of therapeutic interventions

    Genomic comparisons reveal biogeographic and anthropogenic impacts in the koala (Phascolarctos cinereus): a dietary-specialist species distributed across heterogeneous environments

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    The Australian koala is an iconic marsupial with highly specific dietary requirements distributed across heterogeneous environments, over a large geographic range. The distribution and genetic structure of koala populations has been heavily influenced by human actions, specifically habitat modification, hunting and translocation of koalas. There is currently limited information on population diversity and gene flow at a species-wide scale, or with consideration to the potential impacts of local adaptation. Using species-wide sampling across heterogeneous environments, and high-density genome-wide markers (SNPs and PAVs), we show that most koala populations display levels of diversity comparable to other outbred species, except for those populations impacted by population reductions. Genetic clustering analysis and phylogenetic reconstruction reveals a lack of support for current taxonomic classification of three koala subspecies, with only a single evolutionary significant unit supported. Furthermore, similar to 70% of genetic variance is accounted for at the individual level. The Sydney Basin region is highlighted as a unique reservoir of genetic diversity, having higher diversity levels (i.e., Blue Mountains region; AvHe(corr)-0.20, PL% = 68.6). Broad-scale population differentiation is primarily driven by an isolation by distance genetic structure model (49% of genetic variance), with clinal local adaptation corresponding to habitat bioregions. Signatures of selection were detected between bioregions, with no single region returning evidence of strong selection. The results of this study show that although the koala is widely considered to be a dietary-specialist species, this apparent specialisation has not limited the koala's ability to maintain gene flow and adapt across divergent environments as long as the required food source is available

    Notes on Australian mammals. No. 1

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    Volume: 13Start Page: 118End Page: 12

    A redescription of Solomys ("Mus") salamonis Ramsay

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    Volume: 61Start Page: 128End Page: 13

    The early history and relationships of the New Guinea highland dog (Canis hallstromi)

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    Volume: 96Start Page: 93End Page: 9

    A review of the marsupial genus Sminthopsis (Phascogalinae) and diagnoses of new forms

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    Volume: 89Start Page: 307End Page: 32

    Bilbies or Rabbit - Bandicoots

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    tag=1 data=Bilbies or Rabbit - Bandicoots tag=2 data=Troughton, Ellis tag=3 data=Furred Animals of Australia tag=6 data=^d ^m ^y1941 tag=8 data=ANIMALS tag=9 data=BILBIES%RABBIT%BANDICOOTS tag=15 data=BO

    Three new bats of the genera Pteropus, Nyctimene, and Chaerephon from Melanesia

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    Volume: 56Start Page: 204End Page: 20

    Six now Bats (Microchiroptera) from the Australasian Region

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    Volume: 8Start Page: 274End Page: 28
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