Perspective in signed discourse: the privileged status of the signer’s locus and gaze

In gesture studies character viewpoint and observer viewpoint (McNeill 1992) characterize co-speech gestures depending on whether the gesturer’s hand and body imitate a referent’s hand and body or the hand represents a referent in its entirety. In sign languages, handling handshapes and entity handshapes are used in depicting predicates. Narratives in Danish Sign Language (DTS) elicited to make signers describe an event from either the agent’s or the patient’s perspective demonstrate that discourse perspective is expressed by which referent, the agent or the patient, the signers represent at their own locus. This is reflected in the orientation and movement direction of the manual articulator, not by the type of representation in the articulator. Signers may also imitate the gaze direction of the referent represented at their locus or have eye contact with the addressees. When they represent a referent by their own locus and simultaneously have eye contact with the addressee, the construction mixes referent perspective and narrator perspective. This description accords with an understanding of linguistic perspective as grounded in bodily perspective within a physical scene (Sweetser 2012) and relates the deictic and attitudinal means for expressing perspective in sign languages to the way perspective is expressed in spoken languages

A Database for the Future

The Demographic Data Base (DDB) at the Centre for Demographic and Ageing Research (CEDAR) at Umeå University has since the 1970s been building longitudinal population databases and disseminating data for research. The databases were built to serve as national research infrastructures, useful for addressing an indefinite number of research questions within a broad range of scientific fields, and open to all academic researchers who wanted to use the data. A countless number of customised datasets have been prepared and distributed to researchers in Sweden and abroad and to date, the research has resulted in more than a thousand published scientific reports, books, and articles within a broad range of academic fields. While there has long been a clear predominance of research within the humanities and social sciences, it has always been used for research in other fields as well, for example medicine. In this article, we first give a brief presentation of the DDB and its history, characteristics, and development from the 1970s to the present. It includes an overview of the research based on the DDB databases, with a focus on the databases POPUM and POPLINK with individual-level data. A number of major traits of the research from 1973 to now have been outlined, showing the breadth of the research and highlighting some major contributions, with a focus on work that would have been very difficult to perform without data from the DDB

Intergenerational Transfers of Infant Mortality in 19th-Century Northern Sweden

This contribution is part of an international comparative initiative with the aim to assess the analytical power of the Intermediate Data Structure (IDS) in a study of possible intergenerational transmissions of death in infancy. An evaluation of the data in applied research will be useful for further development of the IDS structure and for its future use in comparative research. An additional methodological aim for this part of the study is to evaluate and compare different models for statistical analysis of intergenerational transfers. The analysis is based on a cohort of mothers born 1826-1854, whose experiences of infant mortality are compared to the ones of the previous generation, the grandmothers. Data are collected from Swedish parish records, available in the database POPUM at the Demographic Data Base in Umeå. The analysis shows a clear association between infant mortality among mothers and grandmothers. The probability of an infant death for a woman is increased if her mother also had experienced an infant death. Having tested for different approaches of analysis, we found that simple models with few restrictive assumptions gave similar results as more complicated models. Since it is easy to feel confident in the models with the weakest assumptions, we argue that such models are preferred for this type of analysis

Ny forskning i grammatik

Many Danish cognition verbs take both indicative and infinitive complements. We examine what the contrast between the two complement types codes. The literature offers two answers. One is that the contrast has to do with coreferentiality: if the cognition verb’s primary argument is coreferential with the primary argument of the complement, the complement tends to be infinitive; if not, the complement must be indicative. The other answer concerns the contrast between propositions and states-of-affairs: the indicative complement designates a proposition, the infinitive complement a state-of-affairs. Corpus studies support both answers. They also support an analysis of indicatives as proposition markers. But infinitives cannot – straightforwardly – be analysed as state-of-affairs markers

Kognitionsverber og kontrasten mellem indikativ- og infinitivkomplement

Many Danish cognition verbs take both indicative and infinitive complements. We examine what the contrast between the two complement types codes. The literature offers two answers. One is that the contrast has to do with coreferentiality: if the cognition verb’s primary argument is coreferential with the primary argument of the complement, the complement tends to be infinitive; if not, the complement must be indicative. The other answer concerns the contrast between propositions and states-of-affairs: the indicative complement designates a proposition, the infinitive complement a state-of-affairs. Corpus studies support both answers. They also support an analysis of indicatives as proposition markers. But infinitives cannot – straightforwardly – be analysed as state-of-affairs markers

The Demographic Database — History of Technical and Methodological Achievements

The Demographic Data Base (DDB) at the Centre for Demographic and Ageing Research (CEDAR) at Umeå University has since the 1970s been building longitudinal population databases and disseminating data for research. The databases were built to serve as national research infrastructures, useful for addressing an indefinite number of research questions within a broad range of scientific fields, and open to all academic researchers who wanted to use the data. A countless number of customized datasets have been prepared and distributed to researchers in Sweden and abroad and to date, the research has resulted in more than a thousand published scientific reports, books, and articles within a broad range of academic fields. This article will focus on the development of techniques and methods used to store and structure the data at DDB from the beginning in 1973 until today. This includes digitization methods, database design and methods for linkage. The different systems developed for implementing these methods are also described and to some extent, the hardware used

Cerebrospinal fluid kynurenine and kynurenic acid concentrations are associated with coma duration and long-term neurocognitive impairment in Ugandan children with cerebral malaria

Background: One-fourth of children with cerebral malaria (CM) retain cognitive sequelae up to 2 years after acute disease. The kynurenine pathway of the brain, forming neuroactive metabolites, e.g. the NMDA-receptor antagonist kynurenic acid (KYNA), has been implicated in long-term cognitive dysfunction in other CNS infections. In the present study, the association between the kynurenine pathway and neurologic/cognitive complications in children with CM was investigated. Methods: Cerebrospinal fuid (CSF) concentrations of KYNA and its precursor kynurenine in 69 Ugandan children admitted for CM to Mulago Hospital, Kampala, Uganda, between 2008 and 2013 were assessed. CSF kynurenine and KYNA were compared to CSF cytokine levels, acute and long-term neurologic complications, and long-term cogni‑ tive impairments. CSF kynurenine and KYNA from eight Swedish children without neurological or infectious disease admitted to Astrid Lindgren’s Children’s Hospital were quantifed and used for comparison. Results: Children with CM had signifcantly higher CSF concentration of kynurenine and KYNA than Swedish children (P \u3c 0.0001 for both), and CSF kynurenine and KYNA were positively correlated. In children with CM, CSF kynurenine and KYNA concentrations were associated with coma duration in children of all ages (P = 0.003 and 0.04, respec‑ tively), and CSF kynurenine concentrations were associated with worse overall cognition (P = 0.056) and attention (P = 0.003) at 12-month follow-up in children ≥5 years old. Conclusions: CSF KYNA and kynurenine are elevated in children with CM, indicating an inhibition of glutamatergic and cholinergic signaling. This inhibition may lead acutely to prolonged coma and long-term to impairment of atten‑ tion and cognition