329 research outputs found
Extended Lower Limb Venous Ultrasound for the Diagnosis of Proximal and Distal Vein Thrombosis in Asymptomatic Patients after Total Hip Replacement
AbstractObjective. To assess the performance of extended lower limb venous ultrasound (US) for the diagnosis of asymptomatic deep vein thrombosis (DVT) and to estimate a 3-month DVT incidence on repeated US after total hip replacement.Design. Diagnostic performance study and prospective cohort study.Materials and methods. US was compared to phlebography in 70 consecutive patients and interobserver agreement was assessed in the last 48 patients at day 8. US was repeated in these 48 patients at day 13 and day 90.Results. Phlebography demonstrated a DVT in 18/70 (26%) patients, with five proximal and 13 distal and US in 23/70 (33%) patients, with eight proximal and 15 distal. Sensitivity and specificity of US with 95% CI were 94% (73–100) and 89% (76–96), respectively. Sensitivity in isolated distal vein thrombosis was 92% (67–99). The Kappa coefficient for agreement between observers was 0.84 (0.66–1.00). Follow-up showed a DVT in 15/48 (31%) patients on day 8, in 20/48 patients (42%) on day 13. DVT recurred in two patients during follow-up.Conclusions. The incidence of asymptomatic DVT is still significant despite prophylaxis but most DVTs remain distal and occur in the first 2 weeks. Extended US could replace phlebography for systematic screening in clinical trials using surrogate endpoints in view of its high accuracy and reliability
Narrow-band photodetection based on M-plane GaN films
Rapid identification of a range of hazardous airborne biological and chemical agents requires simultaneous detection at several specific wavelengths, and consequently a set of photodetectors with very narrow-band spectral responsivity. We demonstrate two ultraviolet photodetection configurations based on strained M-plane GaN films on LiAlO2(100) substrates grown by molecular-beam epitaxy with a detection bandwidth below 8 nm. The optical band gap of the film depends on the orientation of the linear polarization of the incident light relative to the c-axis of GaN, which lies in the film plane. The first configuration consists of a polarizationsensitive planar Schottky photodetector and a filter. An orthogonal alignment of the c-axis of the photodetector and the filter produces a detection system with a peak responsivity at 360 nm and a bandwidth of 6 nm. The second one consists of two planar Schottky photodetectors with their c-axes oriented perpendicular to each other. The difference signal between the two photodetectors produces a peak responsivity at 358 nm and a bandwidth of 7.3 nm
Detection of Pathogenic Leptospires in Water and Soil in Areas Endemic to Leptospirosis in Nicaragua
In Nicaragua, there are ideal environmental conditions for leptospirosis. The objective of this investigation was to detect pathogenic and saprophytic leptospires in water and soil samples from leptospirosis-endemic areas in Nicaragua. Seventy-eight water and 42 soil samples were collected from houses and rivers close to confirmed human cases.Leptospiraspp was isolated in Ellinghausen-McCullough-Johnson-Harris (EMJH) culture medium with 5-fluororacil and positive samples were analyzed through PCR for theLipL32gene, specific for pathogenic leptospires (P1 clade). There were 73 positive cultures from 120 samples, however only six of these (5% of all collected samples) were confirmed to be pathogenic, based on the presence of theLipL32gene (P1 clade). Of these six pathogenic isolates, four were from Leon and two from Chinandega. Four pathogenic isolates were obtained from water and two from soil. This study proved the contamination of water and soil with pathogenic leptospires, which represents a potential risk for public health
Predicting the deleterious effects of mutation load in fragmented populations.
Human-induced habitat fragmentation constitutes a major threat to biodiversity. Both genetic and demographic factors combine to drive small and isolated populations into extinction vortices. Nevertheless, the deleterious effects of inbreeding and drift load may depend on population structure, migration patterns, and mating systems and are difficult to predict in the absence of crossing experiments. We performed stochastic individual-based simulations aimed at predicting the effects of deleterious mutations on population fitness (offspring viability and median time to extinction) under a variety of settings (landscape configurations, migration models, and mating systems) on the basis of easy-to-collect demographic and genetic information. Pooling all simulations, a large part (70%) of variance in offspring viability was explained by a combination of genetic structure (F(ST)) and within-deme heterozygosity (H(S)). A similar part of variance in median time to extinction was explained by a combination of local population size (N) and heterozygosity (H(S)). In both cases the predictive power increased above 80% when information on mating systems was available. These results provide robust predictive models to evaluate the viability prospects of fragmented populations
Estimating sigma-meson couplings from D \to 3\pi decays
Using recent experimental evidence from E791 on the sigma meson in D \to 3\pi
decays, we study the relevant couplings in D \to \sigma \pi and \sigma \to \pi\
pi within the accepted theoretical framework for non leptonic D decays. We also
review the linear sigma model, finding that it gives a description which is
consistent with the experimental data.Comment: 6 pages, no figures. Final version accepted for publication as a
Brief Report in Physical Review
On the equivalence between Implicit Regularization and Constrained Differential Renormalization
Constrained Differential Renormalization (CDR) and the constrained version of
Implicit Regularization (IR) are two regularization independent techniques that
do not rely on dimensional continuation of the space-time. These two methods
which have rather distinct basis have been successfully applied to several
calculations which show that they can be trusted as practical, symmetry
invariant frameworks (gauge and supersymmetry included) in perturbative
computations even beyond one-loop order.
In this paper, we show the equivalence between these two methods at one-loop
order. We show that the configuration space rules of CDR can be mapped into the
momentum space procedures of Implicit Regularization, the major principle
behind this equivalence being the extension of the properties of regular
distributions to the regularized ones.Comment: 16 page
Neutron charge form factor at large
The neutron charge form factor is determined from an analysis of
the deuteron quadrupole form factor data. Recent calculations, based
on a variety of different model interactions and currents, indicate that the
contributions associated with the uncertain two-body operators of shorter range
are relatively small for , even at large momentum transfer . Hence,
can be extracted from at large without undue
systematic uncertainties from theory.Comment: 8 pages, 3 figure
Recent Results from PHOBOS at RHIC
The PHOBOS experiment at RHIC has recorded measurements for Au-Au collisions
spanning nucleon-nucleon center-of-mass energies from 19.6 GeV to 200 GeV.
Global observables such as elliptic flow and charged particle multiplicity
provide important constraints on model predictions that characterize the state
of matter produced in these collisions. The nearly 4 pi acceptance of the
PHOBOS experiment provides excellent coverage for complete flow and
multiplicity measurements. Results including beam energy and centrality
dependencies are presented and compared to elementary systems.Comment: 4 pages, 4 figures, proceedings from PANIC02 in Osaka, Japa
Global Observations from PHOBOS
Particle production in Au+Au collisions has been measured in the PHOBOS
experiment at RHIC for a range of collision energies. Three empirical
observations have emerged from this dataset which require theoretical
examination. First, there is clear evidence of limiting fragmentation. Namely,
particle production in central Au+Au collisions, when expressed as
(), becomes energy independent at high energy for a
broad region of around . This energy-independent region grows
with energy, allowing only a limited region (if any) of longitudinal
boost-invariance. Second, there is a striking similarity between particle
production in e+e- and Au+Au collisions (scaled by the number of participating
nucleon pairs). Both the total number of produced particles and the
longitudinal distribution of produced particles are approximately the same in
e+e- and in scaled Au+Au. This observation was not predicted and has not been
explained. Finally, particle production has been found to scale approximately
with the number of participating nucleon pairs for . This scaling
occurs both for the total multiplicity and for high \pT particles (3 <\pT<
4.5 GeV/c).Comment: QM2002 plenary talk, 10 pages, 11 figure
Approximating open quantum system dynamics in a controlled and efficient way: A microscopic approach to decoherence
We demonstrate that the dynamics of an open quantum system can be calculated
efficiently and with predefined error, provided a basis exists in which the
system-environment interactions are local and hence obey the Lieb-Robinson
bound. We show that this assumption can generally be made. Defining a dynamical
renormalization group transformation, we obtain an effective Hamiltonian for
the full system plus environment that comprises only those environmental
degrees of freedom that are within the effective light cone of the system. The
reduced system dynamics can therefore be simulated with a computational effort
that scales at most polynomially in the interaction time and the size of the
effective light cone. Our results hold for generic environments consisting of
either discrete or continuous degrees of freedom
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