Anesthetic Management of a 9-Years-Old Child Affected by Al-Raqad Syndrome Scheduled for Cataract Surgery: A Case Report

Al-Raqad syndrome (ARS) is a novel and extremely rare autosomal recessive disorder. This syndrome affects many organs, mainly the central nervous and musculoskeletal systems. Al-Raqad syndrome’s manifestations include neurodevelopmental delays and a characteristic phenotype including craniofacial anomalies. This disorder, which is the result of a mutation in the Decapping Enzyme, Scavenger (DCPS) gene, was first described in 2015. We present a 9-year-old child affected with this syndrome, who suffers from severe neurodevelopmental delays, scheduled for cataract surgery. The anesthesia management focused on neurodevelopmental defects and craniofacial and musculoskeletal abnormalities. The reports of this syndrome are scarce, and to our knowledge, the present case is the first report of anesthesia management of this syndrome

Garaget- A second living room

This thesis examines the use of a participatory approach to develop a marginalized urban area in the city of Malmö, Sweden. By setting up an innovative, participatory and dialogue oriented meeting place called Garaget, the municipality hopes to strengthen the local community and increase the level of inclusion of the residents into a more sustainable society. Garaget is situated in a place with a history of more than a decade of social projects through the EU URBAN initiative, and has “inherited” the extreme participatory approach of that program. Garaget has also been designed to create a fruitful encounter between the urban social research and the community and as a laboratory for dialogue between community and authorities. Today Garaget functions not only as a community oriented space, but also as a library, café, meeting place and creative workshop, all with the intention to feel as a “second living room”. Although there is no doubt that this living room has been widely used by the local community, especially for holding functions, weddings and other events of social nature, the question whether this participatory approach and dualistic design of public and private space will increase the inclusion of the residents into mainstream society, or if it will just add comfort to the isolation and marginalized position they already inhabit today, is left open and needs further research

The Relationship between Social and Venture Capital in Uppstart Malmo

Today’s the concept of social entrepreneurship; social capital and venture capital are defined by several experts. This case study sets out to gain an understanding of the relation between social capital and venture capital in Uppstart Malmö, a new social entrepreneurial organization which focuses on creating job opportunities in the city of Malmö, where unemployment rate is comparatively high. Analyzing empirical data from interview and other documentation, the results show that Uppstart Malmö is concentrating in the social dimension of enterprise and emphasizing on social capital more than venture capital. While by some means, the foundation is going toward achieving social goal. Uppstart Malmö is not yet an ideal model for completely social organization and commercial signs can be seen in their plans

بررسی مقایسه‌ای تأثیر پخش آوای قرآن با صدای سفید بر نیاز به داروی بیهوشی حین عمل جراحی ویترکتومی

................................Background & Objective: Previous studies have shown that reciting the Quran can reduce anxiety, pain and sympathetic activity. One of the criticisms of these studies was the lack of an appropriate control group. In this study, white sound consisting of all wavelengths audible to humans was used as a control group. Methods: Fifty patients who were candidates for vitrectomy under general anesthesia included in the study. These patients were randomly divided into two groups: Quran Group and White Noise Group. After obtaining informed consent, the associated sound was played to the patients after induction of anesthesia. The two groups were compared in terms of propofol use as an anesthetic to maintain a BIS of about 50, as well as pain, nausea and vomiting. Results: The average consumption of propofol in the Quran group was significantly lower than the white voice group (P-value = 0.05). Also, the rate of nausea and vomiting was lower in the Quran group, but the amount of pain was not significantly different between these two groups. Conclusion: The reciting of the Quran can reduce the need for anesthesia and reduce postoperative nausea and vomiting.سابقه و هدف: مطالعات پیشین نشان داده است که آوای قرآن می‌تواند موجب کاهش اضطراب، درد و فعالیت سمپاتیک گردد؛ ولی نبود گروه کنترل مناسب از مهم‌ترین ایرادهای این نوع از مطالعات است. در پژوهش حاضر اثرات شنیدن آوای قرآن در حین بیهوشی بر عمق بیهوشی بررسی؛ و برای گروه کنترل از صدای سفید که از مجموعۀ تمام طول موج‌های قابل‌شنیدن تشکیل می‌شود، استفاده شد.   روش کار: پژوهش حاضر از نوع کارآزمایی بالینی آینده‌نگر دوسوکور است که برای ۵۰ بیمار داوطلب جراحی ویترکتومی تحت بیهوشی عمومی در اتاق عمل بیمارستان امام حسین (ع) صورت گرفت. بیماران به‌صورت تصادفی به دو گروه قرآن و صدای سفید تقسیم شدند و بعد از القای بیهوشی آوای مرتبط برای بیماران پخش شد. این دو گروه از نظر مصرف پروپوفول به‌عنوان داروی بیهوشی برای حفظ شاخص دو طیفی حدود عدد ۵۰ و همچنین شدت درد، تهوع و استفراغ پس از عمل با یکدیگر مقایسه شدند. در این پژوهش همۀ موارد اخلاقی رعایت شده است و مؤلفان تضاد منافعی گزارش نکردند. یافته‌ها: نتایج نشان می‌دهد که متوسط مصرف پروپوفول در گروه قرآن به‌طور معناداری کمتر از گروه صدای سفید بود (037/0P=). همچنین میزان تهوع و استفراغ در گروه قرآن کمتر بود ولی شدت درد بین این دو گروه اختلاف معنی‌داری نداشت. نتیجه‌گیری: بر اساس یافته‌های به‌دست‌آمده، شنیدن آوای قرآن توسط بیمار تحت بیهوشی عمومی می‌تواند موجب کاهش نیاز به داروی بیهوشی و کاهش بروز تهوع و استفراغ گردد

RETRACTED: Social cognitive theory of gender development and differentiation

AbstractThis article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).This article has been retracted at the request of the Editor.The authors have plagiarized part of a paper that had already appeared in Psychological Review, 106 (1999) 676 – 713. http://dx.doi.org/10.1037/0033-295X.106.4.676. One of the conditions of submission of a paper for publication is that authors declare explicitly that their work is original and has not appeared in a publication elsewhere. Re-use of any data should be appropriately cited. As such this article represents a severe abuse of the scientific publishing system. The scientific community takes a very strong view on this matter and apologies are offered to readers of the journal that this was not detected during the submission process

Behavioral Problems in Juvenile Idiopathic Arthritis: A Controlled Study to Examine the Risk of Psychopathology in a Chronic Pediatric Disorder

Children with juvenile idiopathic arthritis (JIA) are prone to the problems that can delay their psychosocial development; however, the existing literature has not reached a consensus on the psychological problems related to JIA. A total of 51 children and adolescents with JIA and 75 healthy controls aged 6 to 18 years were examined using the Child Behavioral Checklist (CBCL). Our results represented that 70 percent of JIA group reached “borderline clinical” range or “clinical” range in internalizing problems, while this percentage in the control group was 18 percent. In addition, our results indicated that JIA group has gotten significantly higher scores (more than twofold) in externalizing behaviors compared to control group. Furthermore, children with JIA showed higher rate of anxiety/depression, withdrawal/depression, somatic complaints, rule breaking behaviors, and aggressive behaviors as well as thought and social problems compared to control group (p<0.001). As a conclusion, children and adolescents with JIA compared to healthy controls may show higher rate of both internalizing and externalizing problems. Furthermore, our novel findings on externalizing, social, and thought problems in JIA warrant further investigation on affected children who may be at greater risk of future psychopathologies

Survival and outcomes following cardiopulmonary resuscitation; a descriptive study in Iran

Objective: Cardiopulmonary resuscitation (CPR) has been known in its present form since 1960. Different studies have reported variable outcomes among different countries. Therefore, the purpose of this study was to assess the rate of CPR success and the survival rate in managing cardiac arrest among patients in an educational medical center. Methods: This cross-sectional study was performed at Imam Hosein hospital, Tehran, Iran. All patients, admitted to the emergency department with cardiac arrest between March 2007 and January 2008 were included. We used a formerly designed registration form and hospital documentation to retrieve the data of included patients. The main outcomes were the rate of CPR success and the survival rate of these patients. Results: Totally 855 patients were included, from which 510 (59.64%) were males. The mean age of included patients was 63 ± 17.6. The CPR process was successful among 364 (42.58%) patients. A total number of 101 (11.82%) patients were discharged from the hospital. Different factors as the cause of cardiac arrest and past medical problems affected the probability of CPR success and the survival of patients with cardiac arrest. Conclusion: Survival rate at hospital discharge was less than one-third of patients and nearly half of the patients received successful CPR. More intensive care unit (ICU) facilities and educational interventions for the emergency staff and the community can enhance the survival of cardiac arrest patients in our health system

Biological function and molecular mechanism of piRNA in cancer

Cancer is the second leading cause of death globally. piRNAs, which are a novel type of identified small noncoding RNA (ncRNA), play a crucial role in cancer genomics. In recent years, a relatively large number of studies have demonstrated that several piRNA are aberrantly expressed in various kinds of cancers including gastric cancer, bladder cancer, breast cancer, colorectal cancer and Lung cancer and may probably serve as a novel therapeutic target and biomarker for cancer treatment. The present review summarized current advances in our knowledge of the roles of piRNAs in cancer. Keywords: Cancer, PiRNA, Noncoding RNA, Gene silencing, RNA