661 research outputs found
An actin-related protein in Drosophila colocalizes with heterochromatin protein 1 in pericentric heterochromatin
The actin-related proteins have been identified by virtue of their sequence similarity to actin. While their structures are thought to be closely homologous to actin, they exhibit a far greater range of functional diversity. We have localized the Drosophila actin-related protein, Arp4, to the nucleus. It is most abundant during embryogenesis but is expressed at all developmental stages. Within the nucleus Arp4 is primarily localized to the centric heterochromatin. Polytene chromosome spreads indicate it is also present at much lower levels in numerous euchromatic bands. The only other protein in Drosophila reported to be primarily localized to centric heterochromatin in polytene nuclei is heterochromatin protein 1 (HP1), which genetic evidence has linked to heterochromatin-mediated gene silencing and alterations in chromatin structure. The relationship between Arp4 and heterochromatin protein 1 (HP1) was investigated by labeling embryos and larval tissues with antibodies to Arp4 and HP1. Arp4 and HP1 exhibit almost superimposable heterochromatin localization patterns, remain associated with the heterochromatin throughout prepupal development, and exhibit similar changes in localization during the cell cycle. Polytene chromosome spreads indicate that the set of euchromatic bands labeled by each antibody overlap but are not identical. Arp4 and HP1 in parallel undergo several shifts in their nuclear localization patterns during embryogenesis, shifts that correlate with developmental changes in nuclear functions. The significance of their colocalization was further tested by examining nuclei that express mutant forms of HP1. In these nuclei the localization patterns of HP1 and Arp4 are altered in parallel fashion. The morphological, developmental and genetic data suggest that, like HP1, Arp4 may have a role in heterochromatin functions. Keywords: Chromatin, Actin-related protein, Drosophila, Heterochromatin-protein 1, Position effect variegatio
Stability of stationary states in the cubic nonlinear Schroedinger equation: applications to the Bose-Einstein condensate
The stability properties and perturbation-induced dynamics of the full set of
stationary states of the nonlinear Schroedinger equation are investigated
numerically in two physical contexts: periodic solutions on a ring and
confinement by a harmonic potential. Our comprehensive studies emphasize
physical interpretations useful to experimentalists. Perturbation by stochastic
white noise, phase engineering, and higher order nonlinearity are considered.
We treat both attractive and repulsive nonlinearity and illustrate the
soliton-train nature of the stationary states.Comment: 9 pages, 11 figure
INVERSE SCATTERING TRANSFORM ANALYSIS OF STOKES-ANTI-STOKES STIMULATED RAMAN SCATTERING
Zakharov-Shabat--Ablowitz-Kaup-Newel-Segur representation for
Stokes-anti-Stokes stimulated Raman scattering is proposed. Periodical waves,
solitons and self-similarity solutions are derived. Transient and bright
threshold solitons are discussed.Comment: 16 pages, LaTeX, no figure
Quantum virial expansion approach to thermodynamics of He adsorbates in carbon nanotube materials: Interacting Bose gas in one dimension
I demonstrate that He adsorbates in carbon nanotube materials can be
treated as one-dimensional interacting gas of spinless bosons for temperatures
below 8 K and for coverages such that all the adsorbates are in the groove
positions of the carbon nanotube bundles. The effects of adsorbate-adsorbate
interactions are studied within the scheme of virial expansion approach. The
theoretical predictions for the specific heat of the interacting adsorbed gas
are given.Comment: 5 PS figure
Anisotropic Condensation of Helium in Nanotube Bundles
Helium atoms are strongly attracted to the interstitial channels within a
bundle of carbon nanotubes. The strong corrugation of the axial potential
within a channel can produce a lattice gas system where the weak mutual
attraction between atoms in neighboring channels of a bundle induces
condensation into a remarkably anisotropic phase with very low binding energy.
We estimate the binding energy and critical temperature for 4He in this novel
quasi-one-dimensional condensed state. At low temperatures, the specific heat
of the adsorbate phase (fewer than 2% of the total number of atoms) greatly
exceeds that of the host material.Comment: 8 pages, 3 figures, submitted to PRL (corrected typo in abstract
The turn of the valve: representing with material models
Many scientific models are representations. Building on Goodman and Elgin’s notion of representation-as we analyse what this claim involves by providing a general definition of what makes something a scientific model, and formulating a novel account of how they represent. We call the result the DEKI account of representation, which offers a complex kind of representation involving an interplay of, denotation, exemplification, keying up of properties, and imputation. Throughout we focus on material models, and we illustrate our claims with the Phillips-Newlyn machine. In the conclusion we suggest that, mutatis mutandis, the DEKI account can be carried over to other kinds of models, notably fictional and mathematical models
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