Quality of effluent from drains in an aquifer containing saline water

CER64DELM-MWB17.May 1964

Proceedings of the symposium on transient ground water hydraulics

CER63DEM-MWB70.December 1963.Issued with supplements.Errata included.Includes bibliographical references.The symposium was held at Colorado State University in Fort Collins, Colorado on July 25-27, 1963

The structure of EAS at E 0.1 EeV

The ratio of extensive air showers (EAS) total shower energy in the electromagnetic channel (E em) to the size of the shower at maximum development (N max) from a direct measurement of shower longitudinal development using the air fluorescence technique was calculated. The values are not inconsistent with values based upon track length integrals of the Gaisser-Hillas formula for shower development or the known relation between shower energy and size at maximum for pure electromagnetic cascades. Using Linsley's estimates for undetected shower energy based on an analysis of a wide variety of cosmic ray data, the following relation for total shower energy E vs N max is obtained. The Gaisser Hillas implied undetected shower energy fractions

Quasiparticle Relaxation Across a Spin Gap in the Itinerant Antiferromagnet UNiGa5

Ultrafast time-resolved photoinduced reflectivity is measured for the itinerant antiferromagnet UNiGa$_{5}$ ($T_{N} \approx$85 K) from room temperature to 10 K. The relaxation time $\tau$ shows a sharp increase at $T_{N}$ consistent with the opening of a spin gap. In addition, the temperature dependence of $\tau$ below $T_{N}$ is consistent with the opening of a spin gap leading to a quasiparticle recombination bottleneck as revealed by the Rothwarf-Taylor model. This contrasts with canonical heavy fermions such as CeCoIn$_{5}$ where the recombination bottleneck arises from the hybridization gap.Comment: 5 pages, 5 figure

500 TeV gamma rays from Hercules X-1

A signal (chance probability = .0002) with the 1.24 s period of Hercules X-1 has been observed using the Utah Fly's Eye. The signal's relatively long period and high shower energy conflict with some popular models of particle acceleration by pulsars. Optical and X-ray data suggest a picture in which energetic particles produce multi-TeV gamma rays by collisions with Hercules X-1's accretion disk

Dual effect of CTCF loss on neuroprogenitor differentiation and survival

An increasing number of proteins involved in genome organization have been implicated in neurodevelopmental disorders, highlighting the importance of chromatin architecture in the developing CNS. The CCCTC-binding factor (CTCF) is a zinc finger DNA binding protein involved in higher-order chromatin organization, and mutations in the human CTCF gene cause an intellectual disability syndrome associated with microcephaly. However, information on CTCF function in vivo in the developing brain is lacking. To address this gap, we conditionally inactivated the Ctcf gene at early stages of mouse brain development. Cre-mediated Ctcf deletion in the telencephalon and anterior retina at embryonic day 8.5 triggered upregulation of the p53 effector PUMA (p53 upregulated modulator of apoptosis), resulting in massive apoptosis and profound ablation of telencephalic structures. Inactivation of Ctcf several days later at E11 also resulted in PUMA upregulation and increased apoptotic cell death, and the Ctcf-null forebrain was hypocellular and disorganized at birth. Although deletion of both Ctcf and Puma in the embryonic brain efficiently rescued Ctcf-null progenitor cell apoptosis, it failed to improve neonatal hypocellularity due to decreased proliferative capacity of rescued apical and outer radial glia progenitor cells. This was exacerbated by an independent effect of CTCF loss that resulted in depletion of the progenitor pool due to premature neurogenesis earlier in development. Our findings demonstrate that CTCF activities are required for two distinct events in early cortex formation: first, to correctly regulate the balance between neuroprogenitor cell proliferation and differentiation, and second, for the survival of neuroprogenitor cells, providing new clues regarding the contributions of CTCF in microcephaly/intellectual disability syndrome pathologies. © 2014 the authors

Impact of 2009 American Recovery and Reinvestment Act (ARRA) health center investments on disadvantaged neighborhoods after recession

Background: Federally qualified health centers (FQHCs) are integral to the U.S. healthcare safety net and uniquely situated in disadvantaged neighborhoods. The 2009 American Recovery and Reinvestment Act (ARRA) invested $2 billion in FQHC stimulus during the Great Recession; but it remains unknown whether this investment was associated with extended benefits for disadvantaged neighborhoods. Methods: We used a propensity-score matched longitudinal design (2008-2012) to examine whether the 2009 ARRA FQHC investment was associated with local jobs and establishments recovery in FQHC neighborhoods. Job change data were obtained from the Longitudinal Employer-Household Dynamics (LEHD) survey and calculated as an annual rate per 1,000 population. Establishment change data were obtained from the National Neighborhood Data Archive (NaNDA) and calculated as an annual rate per 10,000 population. Establishment data included 4 establishment types: healthcare services, eating/drinking places, retail establishments, and grocery stores. Fixed effects were used to compare annual rates of jobs and establishments recovery between ARRA-funded FQHC census tracts and a matched control group. Results: Of 50,381 tracts, 2,223 contained ≥ 1 FQHC that received ARRA funding. A higher proportion of FQHC tracts had an extreme poverty designation (11.6% vs. 5.4%), high unemployment rate (45.4% vs. 30.3%), and > 50% minority racial/ethnic composition (48.1% vs. 36.3%). On average, jobs grew at an annual rate of 3.84 jobs per 1,000 population (95% CI: 3.62,4.06). In propensity-score weighted models, jobs in ARRA-funded tracts grew at a higher annual rate of 4.34 per 1,000 (95% CI: 2.56,6.12) relative to those with similar social vulnerability. We observed persistent decline in non-healthcare establishments (-1.35 per 10,000; 95% CI: -1.68,-1.02); but did not observe decline in healthcare establishments. Conclusions: Direct funding to HCs may be an effective strategy to support healthcare establishments and some jobs recovery in disadvantaged neighborhoods during recession, reinforcing the important multidimensional roles HCs play in these communities. However, HCs may benefit from additional investments that target upstream determinants of health to mitigate uneven recovery and neighborhood decline.</p