Management of Post COVID 19 Mucormycosis with Osteomyelitis in The Maxilla, New Combined Consequences of The Pandemic. (Case Report).

ABSTRACT: Aim: This case report aims to demonstrate among health providers the importance of timely surgical and prosthetic management procedures of patients who suffered from the newly combined clinical entity of post COVID 19 mucormycosis and osteomyelitis of the palate. Materials and methods: Elaborate advanced diagnosis of the patients including CBCT, MRI, CT, Pathology examination, 3Ds printing reconstruction of the whole skull and digital design of reconstructive mesh that support the prosthesis were carried out. The patients undergone modified infrastructure maxillectomy and immediate prosthetic obturation of the palatal defect that was replaced later by a delayed obturator. Results: Surgical eradication of the necrotic bone and subsequent immediate obturation of the defect minimized morbidly and helped in improving the quality of life of these patients. Conclusion: Early diagnosis of this potentially fatal disease and reach-out a treatment plan immediately, is of prime importance in reducing the morbidly and mortality rate and enhance speech and eating in the two patients reported. It also decreases the psychological impact of this radical surgery

Plants Secondary Metabolites: The Key Drivers of the Pharmacological Actions of Medicinal Plants

The vast and versatile pharmacological effects of medicinal plants are basically dependent on their phytochemical constituents. Generally, the phytochemical constituents of plants fall into two categories based on their role in basic metabolic processes, namely primary and secondary metabolites. Primary plant metabolites are involved in basic life functions; therefore, they are more or less similar in all living cells. On the other hand, secondary plant metabolites are products of subsidiary pathways as the shikimic acid pathway. In the course of studying, the medicinal effect of herbals is oriented towards the secondary plant metabolites. Secondary plant metabolites played an important role in alleviating several aliments in the traditional medicine and folk uses. In modern medicine, they provided lead compounds for the production of medications for treating various diseases from migraine up to cancer. Secondary plant metabolites are classified according to their chemical structures into various classes. In this chapter, we will be presenting various classes of secondary plant metabolites, their distribution in different plant families and their important medicinal uses

Synteny (co-linearity) in some cereal crops genomes as revealed by amplified fragment length polymorphisms (AFLP), simple sequence repeats (SSR) and inter simple sequence repeats (ISSR) markers

Genomes of barley, maize, rice, wheat and sorghum were characterized based on three different mole-cular markers based on DNA sequence namely; Amplified Fragment Length Polymorphisms (AFLP), Simple  Sequence Repeats (SSR) and Inter Simple Sequence Repeats (ISSR) markers. Five AFLP primer combinations were used for fingerprinting six cultivars which belongs to barley, rice and wheat cultivars leading to the  production of numerous AFLP bands, 300 of them were polymorphic. Thirty SSR markers were obtained from  fingerprinting eight cultivars belonging to the five studied species using 11 SSR primers, whereas 91 ISSR  markers were obtained from fingerprinting the same cultivars using 10 ISSR primers. All data were analyzed  using Numerical Taxonomy System of Multivariate Statistical (NTSYS-pc) software packages to address the relationship and studying the synteny between the genomes of the five cereal species. The resulted  dendrogram revealed that rice, barley and wheat genomes are more related to each other than sorghum and maize genomes that appeared close relatedness to each other but distant from other cereal's genomes under study. Barley and wheat genomes revealed close relatedness to each other compared to rice genome.Key words: Amplified fragment length polymorphisms (AFLP), simple sequence repeats (SSR), inter simple sequence repeats (ISSR), wheat, barley, rice, synteny

Interaction of 160 GeV- Muon with Emulsion Nuclei

In this work we present some results of the interaction of high energy muons with emulsion nuclei. The interaction results in emission of a number of fragments as a consequence of electromagnetic dissociation of the excited target nuclei. This excitation is attributed to absorption of photons by the target nuclei due to the intense electric field of the very fast incident muon particles. The interactions take place at impact parameters that allows ultra-peripheral collisions to take place, leading to giant resonances and hence multi-fragmentation of emulsion targets. Charge identification, range, energy spectra, angular distribution and topological cross-section of the produced fragments are measured and evaluatedComment: 13 pages, 4 figures, 4 tables. Accepted for publication in IJMP

Investigations on Recycling Methods of Gypsum Plaster Waste (Review)‎

يحتاج الإنسان إلى الحفاظ على البيئة التي يعيش فيها من أجل أن تبقى مناسبة للحياة للأجيال القادمة. حيث تتسبب الصناعات المختلفة التي يشكلها الإنسان في تلوث البيئة من خلال الطمر بالمخلفات التي تنتج عنها وتتسبب في استهلاك مواد أولية جديدة. من هذه الصناعات، صناعة البورك. حيث يتم إنتاج كمية كبيرة من مخلفات البورك من مجالات مختلفة يتم فيها استخدام البورك. لذلك من الضروري العمل على الحد من هذه النفايات عن طريق إعادة استخدامها أو إعادة تدويرها بأقل التكاليف والإجراءات. تهدف هذه الدراسة إلى مراجعة الطرق المستخدمة لتقليل كمية مخلفات البورك ومعرفة أفضلها. يمكن الاستنتاج أن أفضل الطرق لتقليل كمية مخلفات البورك بإعادة تدويرها بأقل التكاليف أو إعادة استخدامها بدون أي إجراءات مضافة.Humans need to keep on the clean environment in order to refine suitable life for the next generators. Where, the different industries formed by human, cause the environmental pollution by landfill with wastes produced from it and cause the consumption of fresh raw materials. One of these industries, is gypsum plaster industry. Where, a large amount of gypsum plaster waste is produced from different fields that use the gypsum plaster. Therefore, it is necessary to work on reduction of these wastes by reusing or recycling them with the least costs and procedures. This study aims to review the ways used to reduce gypsum waste amount and to figure ant the best among them. It can be concluded that the best ways to reduce the gypsum waste amount are by recycling it with the least costs or reusing it without any additional procedures

Biochemical effects of Resveratrol and Curcumin combination on obese diabetic rats

Abstract Obesity is a global health problem associated with various metabolic disorders as type-2 diabetes, cardiovascular diseases, and oxidative stress. Therefore, utilization of nontoxic natural products represents a logical preventive and/or therapeutic approach for it. The aim of the present article is to evaluate anti-obesity and antioxidant effects of curcumin (50 mg/kg.b.w) and resveratrol (25 mg/kg.b.w) and their combinatorial formulation in obese diabetic rats feed high fat diet (HFD) for 8 consecutive weeks prior. The results of this study also showed that curcumin and resveratrol, both individually and in combination showed antioxidant and anti-obesity actions in experimental diabetic rats for 8 consecutive weeks prior. Indeed, them combination was significantly prevented the increase in the levels of body weight gain, blood glucose, triacylglycerols, total cholesterol, LDL-C, HDL-C, free fatty acids, atherogenic index, thiobarbituric acid reactive substances (TBARS) in the liver tissue and improved the insulin resistance index, reduced glutathione (GSH), glutathione peroxidase (GPx), glutathione reductase (GR) and superoxide dismutase (SOD) when compared to the high fat diet (HFD) control than either agent alone. The results clearly suggest that the combination of dietary curcumin and resveratrol produced a higher anti-obesity, anti-atherogenic, anti-diabetic and antioxidant activities on experimental obese diabetic rats than their individual influences

Follow-up of 50 children after posterior urethral valve management in Al-Azhar University Hospitals

Objective: This study was performed to assess the various clinical presentations, complications, and surgical management, as well as follow-up, of patients with posterior urethral valve (PUV).Patients and methods: This is a prospective descriptive analysis of the data of 50 patients with PUVs of different age reviewed. Serum creatinine levels, clinical examination, abdominopelvic ultrasound, and magnetic resonance urography were performed, and the diagnosis was confirmedby voiding cystourethrography. The patients were divided into two categories: primary intervention and surgical intervention.Results: A total of 50 boys with a mean age at diagnosis of 100 ±15 days were included in this work. The most common presentation in patients managed by valve ablation was difficult micturition (60%), whereas in patients managed by initial vesicostomy the most common presentation was febrile urinary tract infection (67%). Vesicoureteral reflux presented in 61.2% and hydronephrosis in 82.6%, whereas complications occurred in three (6%) children. Mortality occurred in five (10%) patients. Postoperative improvement of hydronephrosis grade in both categories is not appreciably different.Conclusion: Urinary drainage using small catheters or nasogastric tube in the early days of infancy followed by valve ablation is the best treatment modality in PUV.Keywords: children, outcome, posterior urethral valve, urinary drainage valve ablation, vesicostom

Human Impacts on Coral Reef Ecosystem

Healthy, Coral reefs are the most spectacular, diverse and economically valuable marine ecosystems on the planet, Complex and productive, coral reefs are extremely important for biodiversity, providing a home to 35,000–60,000 species of plants and animals (over 25% of all marine life), many of which are not described by science. They are also vital for people and business. They provide nurseries for many species of commercially important fish, protection of coastal areas from storm waves. They are providing hundreds of billions of dollars in food, jobs and significant attraction for the tourism industry. Yet coral reef ecosystems have undergone phase shifts to alternate, degraded assemblages because of the combined human activates of unsustainable overfishing, intensive tourism, urbanization, sedimentation, declining water quality, pollution and primarily from the direct and indirect impacts of climate change. Most coral ecologists confirm that coral reef degradation has increased dramatically during the last three decades due to enhanced anthropogenic disturbances and their interaction with natural stressors. So, it is necessary to recognize the threats facing coral reefs from anthropogenic activities and try to minimize and mitigate these impacts