Assessment of phacoaspiration techniques in clear lens extraction for correction of high myopia

Mostafa A El-Helw, Ahmed M EmarahDepartment of Ophthalmology, Cairo University, EgyptPurpose: To evaluate various phacoaspiration techniques in clear lens extraction for the incidence of intraoperative difficulties and complications.Patients and methods: This was a prospective study in which bilateral clear lens extraction was performed on 40 eyes of 20 patients, to correct high myopia. The patients were divided into 2 groups: group A underwent supracapsular phacoaspiration; group B were the contralateral eyes of the same patient. These patients were operated on with endocapsular phacoaspiration with the divide and conquer (D and C) technique. Preoperative ocular examination data were recorded and tested for significance. Intraoperative difficulties and complications such as nucleus cracking, capsule rupture and vitreous loss, and repeated chamber collapse were recorded. Postoperative examination data were recorded.Results: Mean age was 35.65 ± 5.85 years. Mean follow-up time was 17.1 ± 8.56 months. In group A mean myopia was -17.3 ± 5.07 diopters; in group B myopia was -17.9 ± 4.20 diopters. Mean preoperative uncorrected visual acuity (UCVA) was 0.04 ± 0.0167, while the mean postoperative UCVA was 0.435 ± 0.1442. There was a significant difference in pre and postoperative BCVA within both groups, but not between the two groups. In both groups endothelial cell count (ECC) showed a significant difference between pre- and postoperative data; however, there was no statistically significant difference between both groups in postoperative ECC. The effective phacoaspiration time for group A was 4.6 ± 1.6 seconds, and for group B 9.90 ± 2.27 seconds (P < 0.005). No cases of capsule rupture occurred in group A, but 3 cases occurred in group B (15 %) (not significant, P = 0.231). Nucleus cracking did not occur in group A, but in group B 13 cases occurred (65%). Chamber collapse occurred in 4 cases (20%) in group A and 5 cases (25%) in group B (not significant, P = 1.000). Three cases of moderate postoperative iritis were recorded in group B in (15%), in which posterior capsular rupture also occurred. No cases of iritis were recorded in group A (not significant, P = 0.231). Two cases of cystoid macular edema were recorded in group B (10%) and none in group A (not significant, P = 0.487).Conclusions: Supracapsular phacoaspiration for clear lens extraction in correction of high myopia seems to present no risk for the posterior capsule, although there is a marginal risk to the ECC.Keywords: clear lens extraction, correction of high myopia, supracapsular phacoaspiratio

Query Optimization in Dynamic Environments

Most modern applications deal with very large amounts of data. Having to deal with such huge amounts of data is in itself a challenge. This challenge is complicated even more by the fact that, in many cases, this data is constantly changing and evolving. For instance, relational databases that handle the data of day-to-day transactional applications often have tables with very high data change rates. It is not uncommon to even have temporary or volatile tables that get created from scratch and completely dropped over the course of one query workload. This dissertation focuses on optimizing structured queries over dynamic and constantly changing data sets. Our work address this issue, and some of the challenges related to it. We address the issue of database statistics becoming stale and inaccurate due to constantly changing data. We introduce ways to automatically analyze the existing statistics and recommend and collect the necessary statistics to optimize a single query or a query workload. We introduce a mechanism to automate the recommendation and collection of statistical views for a given query workload. We also compare two methods of using these statistical views in selectivity estimation. We evaluate our methods and techniques with experimental studies using prototypes that we built into commercial database systems

Predictability and stability of refraction with increasing optical zone diameter in hyperopic LASIK

Mostafa A El-Helw, Ahmed M EmarahCairo University, Cairo, EgyptObjective: We undertook a prospective nonrandomized study to assess refractive outcome and patient satisfaction with hyperopic laser in situ keratomileusis (LASIK) using variable optical zone diameters in correction of hyperopia of more than 4.00 diopters.Methods: Fourteen adults (comprising 28 hyperopic eyes) underwent hyperopic LASIK correction for hyperopia of more than 4.00 diopters. The sample was divided into two groups. Group 1 included the right eyes of the 14 patients who underwent hyperopic LASIK using a 6.5 mm optical zone diameter. Group 2 comprised the left eyes of the same patients with the only difference being that the optical zone diameter was 6.0 mm.Results: The mean age of the patients was 36.42 ± 5.10 years. Group 1 eyes had a median (range) preoperative uncorrected visual acuity (UCVA) of 0.79 (0.52) and best-corrected visual acuity (BCVA) of 0.15 (0.08). Group 2 had a median preoperative UCVA of 0.79 (0.60) and BCVA of 0.15 (0.08). The median postoperative UCVA in Group 1 was 0.17 (0.21) and BCVA was 0.15 (0.13). In Group 2, the median postoperative UCVA was 0.30 (0.32) and BCVA was 0.15 (0.26). Group 1 had a median preoperative refraction of +5.37 (1.75) diopters and the median postoperative refraction at one week was −0.23 (1.25) diopters, at three months was +0.75 (0.75) diopters, and at six months was +0.75 (1.00) diopters. Group 2 had a median preoperative refraction of +5.00 (1.75) diopters, and the median postoperative refraction at one week was +0.13 (1.5) diopters, at three months was +1.00 (0.75) diopters and at six months +1.25 (1.25) diopters. The difference was statistically significant between groups 1 and 2. The difference within each group was also significant. Group 1 eyes were stabilizing after the three-month period in contrast with Group 2 in which the refractive changes continued throughout the follow-up period.Conclusion: Larger optical zone diameter in correction of hyperopia of more than 4.00 diopters was more predictable, stable and safe.Keywords: hyperopia, LASIK, optical zone, refractio

Small-Cell Lung Cancer: 8 Years Experience of a Single Multidisciplinary Team

Aims. We have audited the changes in treatment practice for small-cell lung cancer (SCLC) presented to a single multidisciplinary team (MDT) at Doncaster and Bassetlaw Hospitals between January 1998 and December 2005. Materials and Methods. The MDT database was used to identify all patients with SCLC. Anonymised demographic, treatment, and outcome details were extracted from the database supplemented by patient records. Results. 235 patients were identified. 112 (48%) had limited disease at presentation. Chemotherapy was the initial treatment for 195 patients, 77% of whom had a documented radiological response with a complete response in 24%. Chemotherapy regimes evolved during the study period with the increasing use of platinum-based chemotherapy. Anthracycline-based chemotherapy was most used before 2004 and was given to 57% of all patients. 42% received consolidation thoracic radiotherapy and 24% prophylactic cranial irradiation. The median and 2-year survival were 8 months and 18%, respectively, for patients with limited disease and 5 months and 5%, respectively, for extensive disease. Conclusion. We have documented changes in treatment practice and service delivery of SCLC over the 8 years during which the MDT has been operating. However, there has not achieve any significant improvement in outcome for the population of patients with SCLC

COMPARISON OF MPPT ALGORITHMS FOR PHOTOVOLTAIC SYSTEMS UNDER UNIFORM IRRIADIANCE BETWEEN PSO AND P&O

This paper shows a Comparison between Conventional Method [P&O] and particle swarm optimization [PSO] Based on MPPT Algorithms for Photovoltaic Systems under uniform irradiance and temperature. The main idea is to show that PSO method has a very high tracking speed and has the ability to track MPP under different environmental conditions in addition to an easy hardware implementation using a low-cost microcontroller. MATLAB simulations are carried out under very challenging conditions, namely irradiance and temperature, which reflect a change in the load [KW]. The proposed PSO tracking method Results will be compared with conventional method called [P&O] through MATLAB/SIMULINK

A Hybrid Adaptive Compressive Sensing Model for Visual Tracking in Wireless Visual Sensor Networks

The employ of Wireless Visual Sensor Networks (WVSNs) has grown enormously in the last few years and have emerged in distinctive applications. WVSNs-based Surveillance applications are one of the important applications that requires high detection reliability and robust tracking, while minimizing the usage of energy to maximize the lifetime of sensor nodes as visual sensor nodes can be left for months without any human interaction. The constraints of WVSNs such as resource constraints due to limited battery power, memory space and communication bandwidth have brought new WVSNs implementation challenges. Hence, the aim of this paper is to investigate the impact of adaptive Compressive Sensing (CS) in designing efficient target detection and tracking techniques, to reduce the size of transmitted data without compromising the tracking performance as well as space and energy constraints. In this paper, a new hybrid adaptive compressive sensing scheme is introduced to dynamically achieve higher compression rates, as different datasets have different sparsity nature that affects the compression. Afterwards, a modified quantized clipped Least Mean square (LMS) adaptive filter is proposed for the tracking model. Experimental results showed that adaptive CS achieved high compression rates reaching 70%, while preserving the detection and tracking accuracy which is measured in terms of mean squared error, peak-signal-to-noise-ratio and tracking trajectory

Use of STATCOM in wind farms with fixed-speed generators for grid code compliance

The increasing penetration of wind energy into power systems has pushed grid operators to set new requirements for this kind of generating plants in order to keep acceptable and reliable operation of the system. In addition to the low voltage ride through capability, wind farms are required to participate in voltage support, stability enhancement and power quality improvement. This paper presents a solution for wind farms with fixed-speed generators based on the use of STATCOM with braking resistor and additional series impedances, with an adequate control strategy. The focus is put on guaranteeing the grid code compliance when the wind farm faces an extensive series of grid disturbances

High-dose chemotherapy and peripheral blood stem cell support in refractory gestational trophoblastic neoplasia

We present retrospectively our experience in the use of high-dose chemotherapy and haematopoietic stem cell support (HSCS) for refractory gestational trophoblastic neoplasia (GTN) in the largest series so far reported. In all, 11 patients have been treated at three Trophoblast Centres between 1993 and 2004. The conditioning regimens comprised either Carbop-EC-T (carboplatin, etoposide, cyclophosphamide, paclitaxel and prednisolone) or CEM (carboplatin, etoposide and melphalan) or ICE (ifosfamide, carboplatin, etoposide). Two patients had complete human chorionic gonadotrophin responses, one for 4 and the other for 12 months. Three patients had partial tumour marker responses for 1–2 months. High-dose chemotherapy and HSCS for GTN is still unproven. Further studies are needed, perhaps in high-risk patients who fail their first salvage treatment