Potensi Daun Pacar Air (Impatiens balsamina L.) dalam Menghambat Pertumbuhan Jamur Rhizopus oryzae L.

Pacar air (Impatiens balsamina L.) plant belongs to the Balsaminaceae family and is used as an indigenous medicine in Asia for fingernail inflammation, fractures, and rheumatism treatments. Moreover, the antipruritic, antianaphylactic, antifungal, antibacterial, and antitumor activities of some compounds, especially phenolics and quinones from this plant have been studied extensively. Therefore, this study aims to determine the antifungal activity of Pacar air leaves (Impatiens balsamina L.) methanol extract against Rhizopus oryzae L. and the IC50 value. The results showed that an increase in the concentrations of I. balsamina L. leaves methanol extract significantly raised the fungal growth. Furthermore, the extract inhibition against R. oryzae L. at various concentrations of 0.5; 0.7; 0.9; 1.1; and 1.3% w/v were 10, 21.9, 58.06, 68.06, and 79.72%, respectively, while the IC50 value was 0.896%. Hence, the presence of naphthoquinones and other secondary metabolites are responsible for its antifungal activity. Based on these results, the antifungal potential of I. balsamina L. leaves against soft-rot fungi is useful in the future

AKTIVITAS ANTIJAMUR PELAPUK KAYU NANOPARTIKEL KITOSAN-EKSTRAK N-HEKSAN DAGING BUAH KAYU GADIS (Cinnamomum parthenoxylon)

This study aims to synthesize chitosan nanoparticles - n-hexane extract of Cinnamomum parthenoxylon (CP) fruit using the ionic gelation method, to characterize them, and to determine their antifungal activity against the wood-rotting fungi Trametes versicolor and Fomitopsis palustris. Chitosan-CP extract nanoparticles were formulated with chitosan:Na-TPP:CP extract ratio of 1:1:0.5. Particle size and polydispersity index were determined using a particle size analyzer (PSA), and particles morphology was observed using a scanning electron microscope (SEM), and antifungal activity was measured using agar media. The results revealed that the average size of chitosan nanoparticles (base) was 276.9 nm, while the average size of chitosan-CP extract nanoparticles was 807.6 nm. The polydispersity index (PI) of both nanoparticles was greater than 0.7. Observations of the nanoparticles' morphology revealed that aggregation/agglomeration formed in the resulting particles. Both nanoparticles chitosan (base) and chitosan-CP extract inhibited the growth of white rot fungi (T. versicolor) more than brown rot fungi (F. palustris), as measured by the inhibitory zone

UJI AKTIVITAS ANTI JAMUR EKSTRAK METANOL DAUN PACAR AIR (Impatiens balsamina L.) TERHADAP JAMUR Rhizopus oryzae L.

Penelitian bertujuan untuk menentukan aktivitas anti jamur dari ekstrak metanoldaun pacar air (Impatiens balsamina L.) terhadap pertumbuhan jamur Rhizopusoryzae L dan menentukan nilai IC nya. Pengujian aktivitas anti jamur dilakukandengan variasi konsentrasi ekstrak 0% (kontrol); 0,5%; 0,7%; 0,9%; 1,1%; dan1,3%. Aktivitas anti jamur ekstrak metanol daun pacar air memperlihatkansemakin tinggi konsentrasi ekstrak metanol daun pacar air yang digunakan, makapersentase daya hambat pertumbuhan jamur Rhizopus oryzae L. semakin besar.Berdasarkan hasil analisis uji one way ANOVA diperoleh hasil H 50 0 ditolak dan H diterima yang berarti pemberian ekstrak metanol daun pacar air berpengaruhnyata terhadap persentase daya hambat pertumbuhan jamur Rhizopus oryzae L., sehingga analisis dilanjutkan dengan uji lanjut Duncan. Dari uji lanjut Duncan diperoleh kontrol dan variasi konsentrasi yang digunakan berbeda nyata antarperlakuan dan didapatkan persentase daya hambat terbesar pada konsentrasi 1,3% dengan daya hambat sebesar 79,72%. Dari persamaan regresi linear diperolehnilai IC pada konsentrasi 0,87%. 50