Effects of Incorporation of Sainfoin (\u3ci\u3eOnobrychis viciafolia\u3c/i\u3e Scop.) with Cool Season Grasses on \u3ci\u3ein vitro\u3c/i\u3e Digestibility and CH4 Emission

Sainfoin (Onobrychis viciafolia Scop.) is an important non-bloating perennial leguminous forage. The tannins in sainfoin alter protein metabolism in the rumen and have been implicated in altering both nitrous oxide and methane emissions. However, the effect of sainfoin when mixed with cool-season forages is unknown. Therefore, in this study, we evaluated the in-vitro fermentation of sainfoin hay mixed with two other perennial cool-season forages, meadow bromegrass and orchardgrass at five ratios (0:100, 25:75, 50:50, 75:50, and 100:0). Data on dry matter disappearance (DMD), neutral detergent fiber disappearance (NDFD), gas production (GP) methane (CH4) emissions, and ammonia production were collected 48 h post incubation. Ruminal fluid was sourced from three heifers fed with forage hay. Incubations were conducted with and without PEG (polyethylene glycol) as PEG negates the biological activity of tannins. Sainfoin had a higher nutritive value than the other two grass species as evidenced by the higher proportion of total nitrogen and lower proportion of ADF and NDF. The change in DMD, ammonia-N, NDFD, GP, and CH4 emissions between sainfoin and grass only hay were 3.1, 9.2, -36.8, -1.76, and -1.2% respectively with the intermediate results for the mixture. The inclusion of sainfoin with cool-season grasses has positive effects on ruminal fermentation and lowered in vitro methane emissions as compared to grass alon

Light-controlled reversible modulation of frontier molecular orbital energy levels in trifluoromethylated diarylethenes

Among bistable photochromic molecules, diarylethenes (DAEs) possess the distinct feature that upon photoisomerization they undergo a large modulation of their pelectronic system, accompanied by a marked shift of the HOMO/LUMO energies and hence oxidation/reduction potentials. The electronic modulation can be utilized to remote-control charge-as well as energy-transfer processes and it can be transduced to functional entities adjacent to the DAE core, thereby regulating their properties. In order to exploit such photoswitchable systems it is important to precisely adjust the absolute position of their HOMO and LUMO levels and to maximize the extent of the photoinduced shifts of these energy levels. Here, we present a comprehensive study detailing how variation of the substitution pattern of DAE compounds, in particular using strongly electron-accepting and chemically stable trifluoromethyl groups either in the periphery or at the reactive carbon atoms, allows for the precise tuning of frontier molecular orbital levels over a broad energy range and the generation of photoinduced shifts of more than 1 eV. Furthermore, the effect of different DAE architectures on the transduction of these shifts to an adjacent functional group is discussed. Whereas substitution in the periphery of the DAE motif has only minor implications on the photochemistry, trifluoromethylation at the reactive carbon atoms strongly disturbs the isomerization efficiency. However, this can be overcome by using a nonsymmetrical substitution pattern or by combination with donor groups, rendering the resulting photoswitches attractive candidates for the construction of remote-controlled functional systems

Integrated Water Resources Management in Cities in the World: Global Challenges

This is the final version. Available on open access from Springer via the DOI in this recordData Availability: The authors declare that all the data supporting the findings of this study are included in its Supplementary Information.Water scarcity and accessibility remain persistently amongst the most prominent global challenges. Although there is a wide agreement among international organizations that Integrated Water Resources Management (IWRM) and water governance are key to overcome water-related challenges, global assessments of the progress made by cities is lacking. This paper for the first time analyses the challenges of water, wastewater, municipal solid waste and climate change in cities. We used empirical studies (125 cities) based on the City Blueprint Approach and developed a statistical estimation model to estimate IWRM performances of another 75 cities. These 200 cities in total represent more than 95% of the global urban population. This comprehensive global picture enables us to evaluate the existing gaps in achieving water-related Sustainable Development Goals (SDGs), in particular SDG 6 (clean water and sanitation) and SDG 11 (sustainable cities and communities). The best performing cities were Amsterdam and Singapore. Unfortunately, most cities do not yet manage their water resources wisely and are far from achieving the SDGs. For instance, targets regarding drinking water supply are still a challenge for many cities in Africa and Asia and challenges regarding sanitation are high in cities in Africa, Asia and Latin America. The same holds for solid waste management, climate adaptation, and people living in informal settlements. In another paper we will address the solution pathways to these global challenges

One third of African rivers fail to meet the ’good ambient water quality’ nutrient targets

The ambition of Sustainable Development Goal (SDG) target 6.3 is to improve global water quality by 2030. SDG indicator 6.3.2 monitors progress towards this target by assessing water bodies against ‘good’ ambient water quality criteria, with nutrients (nitrogen and phosphorus) as part of the key metrics. However, large data gaps present a fundamental challenge, especially for Africa on how to assess the progress being made with respect to both the current and desired future situations. Here, a continental water quality model for Africa is presented to simulate river sediment load, Total Nitrogen (TN) and Total Phosphorus (TP) loads and concentrations. Furthermore, critical areas and hotspots of TN and TP pollution are mapped for the period 2017 – 2019, in relation to the United Nations Environment Programme (UNEP) target thresholds used for the assessment of SDG indicator 6.3.2. Utilizing the UNEP’s criteria, which designates a water body as having “good ambient water quality” if 80% or more of its monitored values meet their targets, it is estimated that 44 % and 15 % of African rivers fail to meet the set water quality thresholds for simulated TP and TN, respectively. When synthesizing data for both TP and TN, 34 % of the rivers do not qualify as having “good ambient water quality”. Geographically, the most pronounced nutrient pollution hotspots were in North Africa, Niger River Delta, Nile River basin, Congo River basin and specific zones in Southern Africa. These areas correlate with regions characterized by high inputs of fertilizers, manure and wastewater discharge

University of Minnesota aquifer thermal energy storage (ATES) project report on the third long-term cycle

The University of Minnesota aquifer thermal energy storage (ATES) system has been operated as a field test facility (FTF) since 1982. The objectives were to design, construct, and operate the facility to study the feasibility of high-temperature ATES in a confined aquifer. Four short-term and two long-term cycles were previously conducted, which provided a greatly increased understanding of the efficiency and geochemical effects of high-temperature aquifer thermal energy storage. The third long-term cycle (LT3) was conducted to operate the ATES system in conjunction with a real heating load and to further study the geochemical impact that heated water storage had on the aquifer. For LT3, the source and storage wells were modified so that only the most permeable portion, the Ironton-Galesville part, of the Franconia-Ironton-Galesville aquifer was used for storage. This was expected to improve storage efficiency by reducing the surface area of the heated volume and simplify analysis of water chemistry results by reducing the number of aquifer-related variables which need to be considered. During LT3, a total volume of 63.2 {times} 10{sup 3} m {sup 3} of water was injected at a rate of 54.95 m{sup 3}/hr into the storage well at a mean temperature of 104.7{degrees}C. Tie-in to the reheat system of the nearby Animal Sciences Veterinary Medicine (ASVM) building was completed after injection was completed. Approximately 66 percent (4.13 GWh) of the energy added to the aquifer was recovered. Approximately 15 percent (0.64 GWh) of the usable (10 building. Operations during heat recovery with the ASVM building`s reheat system were trouble-free. Integration into more of the ASVM (or other) building`s mechanical systems would have resulted in significantly increasing the proportion of energy used during heat recovery

Alternatively spliced tissue factor and full-length tissue factor protect cardiomyocytes against TNF-α-induced apoptosis

Tissue Factor (TF) is expressed in various cell types of the heart, such as cardiomyocytes. In addition to its role in the initiation of blood coagulation, the TF:FVIIa complex protects cells from apoptosis. There are two isoforms of Tissue Factor (TF): “full length” (fl)TF – an integral membrane protein; and alternatively spliced (as)TF – a protein that lacks a transmembrane domain and can thus be secreted in a soluble form. Whether asTF or flTF affect apoptosis of cardiomyocytes is unknown