Congenital cardiac malformations in Iceland from 1990 through 1999

To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldINTRODUCTION AND BACKGROUND: About 1% of live-born children have congenital malformations of the heart. The aim of our study was to investigate the incidence of such defects in children born in Iceland during a period of 10 years, extending from 1990 through 1999. MATERIALS AND METHODS: Information about the patients was obtained from medical records from two hospitals that cover the whole country, a private clinic of pediatric cardiologists, an echocardiography database, autopsy reports, and death certificates. We investigated the distribution of specific malformations, the age at diagnosis, the symptoms leading to the diagnosis, the source of referral, and treatment and quality of life. RESULTS: Between 1990 and 1999, there were 44,013 live births in Iceland, of which 740 patients were diagnosed with congenital cardiac malformations, accounting for 1.7% of the live-born children. The distribution was made up of 338 patients with ventricular septal defect (45.7%), 90 with atrial septal defect (12.2%), 85 with patency of the arterial duct (11.5%), 48 with pulmonary valvar stenosis (6.5%), 38 with a bicuspid aortic valve (5.1%), 28 with aortic coarctation (3.8%), 22 with tetralogy of Fallot (3.0%), 14 with transposed great arteries (1.9%), 11 with aortic stenosis (1.5%), 10 with atrioventricular septal defect and common atrioventricular orifice (1.4%), 9 with mitral valvar regurgitation (1.2%), 7 with sub-aortic stenosis (0.9%), and 5 with hypoplasia of the left heart (0.7%). Extracardiac anomalies were seen in 89 patients (12.0%). Chromosomal defects were seen in 36 patients, of whom 28 had Down's syndrome. DISCUSSION: The annual incidence of diagnosis of patients with congenital cardiac malformations increased during the period of study. This was noted for minor defects, but the incidence of the major anomalies did not alter. Our observed yearly incidence, at 1.7%, was higher than noted in a previous study covering the years 1985 through 1989, and is also higher than in other population-based studies. The most likely explanation is the fact that access to pediatric cardiologists in Iceland is very good. Diagnosis, registration, and follow-up are conducted by only a few cardiologists, and take place at a single center for pediatric cardiology

Solar forcing of Holocene summer sea-surface temperatures in the northern North Atlantic

Mounting evidence from proxy records suggests that variations in solar activity have played a significant role in triggering past climate changes. However, the mechanisms for sun-climate links remain a topic of debate. Here we present a high-resolution summer sea-surface temperature (SST) record covering the past 9300 yr from a site located at the present-day boundary between polar and Atlantic surface-water masses. The record is age constrained via the identification of 15 independently dated tephra markers from terrestrial archives, circumventing marine reservoir age variability problems. Our results indicate a close link between solar activity and SSTs in the northern North Atlantic during the past 4000 yr; they suggest that the climate system in this area is more susceptible to the influence of solar variations during cool periods with less vigorous ocean circulation. Furthermore, the high-resolution SST record indicates that climate in the North Atlantic regions follows solar activity variations on multidecadal to centennial time scales

Variability of the North Atlantic Current during the last 2000 years based on shelf bottom water and sea surface temperatures along an open ocean/shallow marine transect in western Europe

Marine localities on the west European shelf have been studied to reconstruct the nearshore palaeoceanography of the last two millennia. The sites form a transect from the Iberian margin northeastward via Scotland to western Norway and Iceland. Proxies used for palaeoclimatic reconstructions include stable isotopes, benthic and planktonic foraminfera, diatoms, dinoflagellates, as well as geochemical and sedimentological parameters. Major changes as well as long-term trends in oceanographic conditions are observed in the records, including a general cooling trend through much of the last millennium. There is a clear linkage between the atmospheric processes and the oceanic circulation, and the ocean temperature variability in the records can be correlated with the so-called 'Mediaeval Warm Period' and 'Little Ice Age'. These oscillations are, however, by no means unique within the last two millennia. As an example, sea surface temperatures to the north of Iceland and on the Iberian margin were higher in the Roman Warm Period than at any time during the 'Mediaeval Warm Period'. However, the palaeoceanographic record generally supports a distinct cooling at the transition between the 'Mediaeval Warm Period' and the 'Little Ice Age'. While a number of records indicate a warming of coastal and shelf waters during the last 200 years, the twentieth century does not appear to be unusual when the proxy records spanning the last two millennia are examined.</p

Reconstructions of surface ocean conditions from the northeast Atlantic and Nordic seas during the last millennium

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