A systematic literature review on the code smells datasets and validation mechanisms

The accuracy reported for code smell-detecting tools varies depending on the dataset used to evaluate the tools. Our survey of 45 existing datasets reveals that the adequacy of a dataset for detecting smells highly depends on relevant properties such as the size, severity level, project types, number of each type of smell, number of smells, and the ratio of smelly to non-smelly samples in the dataset. Most existing datasets support God Class, Long Method, and Feature Envy while six smells in Fowler and Beck's catalog are not supported by any datasets. We conclude that existing datasets suffer from imbalanced samples, lack of supporting severity level, and restriction to Java language.Comment: 34 pages, 10 figures, 12 tables, Accepte

MOLECULAR SURVEILLANCE OF Plasmodium vivax AND Plasmodium falciparum DHFR MUTATIONS IN ISOLATES FROM SOUTHERN IRAN

In Iran, both Plasmodium vivax and P. falciparum malaria have been detected, but P. vivax is the predominant species. Point mutations in dihydrofolate reductase (dhfr) gene in both Plasmodia are the major mechanisms of pyrimethamine resistance. From April 2007 to June 2009, a total of 134 blood samples in two endemic areas of southern Iran were collected from patients infected with P. vivax and P. falciparum. The isolates were analyzed for P. vivax dihydrofolate reductase (pvdhfr) and P. falciparum dihydrofolate reductase (pfdhfr) point mutations using various PCR-based methods. The majority of the isolates (72.9%) had wild type amino acids at five codons of pvdhfr. Amongst mutant isolates, the most common pvdhfr alleles were double mutant in 58 and 117 amino acids (58R-117N). Triple mutation in 57, 58, and 117 amino acids (57L/58R/117N) was identified for the first time in the pvdhfr gene of Iranian P. vivax isolates. All the P. falciparumsamples analyzed (n = 16) possessed a double mutant pfdhfrallele (59R/108N) and retained a wild-type mutation at position 51. This may be attributed to the fact that the falciparum malaria patients were treated using sulfadoxine-pyrimethamine (SP) in Iran. The presence of mutant haplotypes in P. vivax is worrying, but has not yet reached an alarming threshold regarding drugs such as SP. The results of this study reinforce the importance of performing a molecular surveillance by means of a continuous chemoresistance assessment

PANC Study (Pancreatitis: A National Cohort Study): national cohort study examining the first 30 days from presentation of acute pancreatitis in the UK

Abstract Background Acute pancreatitis is a common, yet complex, emergency surgical presentation. Multiple guidelines exist and management can vary significantly. The aim of this first UK, multicentre, prospective cohort study was to assess the variation in management of acute pancreatitis to guide resource planning and optimize treatment. Methods All patients aged greater than or equal to 18 years presenting with acute pancreatitis, as per the Atlanta criteria, from March to April 2021 were eligible for inclusion and followed up for 30 days. Anonymized data were uploaded to a secure electronic database in line with local governance approvals. Results A total of 113 hospitals contributed data on 2580 patients, with an equal sex distribution and a mean age of 57 years. The aetiology was gallstones in 50.6 per cent, with idiopathic the next most common (22.4 per cent). In addition to the 7.6 per cent with a diagnosis of chronic pancreatitis, 20.1 per cent of patients had a previous episode of acute pancreatitis. One in 20 patients were classed as having severe pancreatitis, as per the Atlanta criteria. The overall mortality rate was 2.3 per cent at 30 days, but rose to one in three in the severe group. Predictors of death included male sex, increased age, and frailty; previous acute pancreatitis and gallstones as aetiologies were protective. Smoking status and body mass index did not affect death. Conclusion Most patients presenting with acute pancreatitis have a mild, self-limiting disease. Rates of patients with idiopathic pancreatitis are high. Recurrent attacks of pancreatitis are common, but are likely to have reduced risk of death on subsequent admissions. </jats:sec

A study on respiratory problems and pulmonary function indexes among cement industry workers in Mashhad, Iran

Background: The respiratory system is the most vulnerable system in the cement industry. This study was conducted to determine the effects of occupational exposure to cement dust on the respiratory system more thoroughly. Material and Methods: In this cross sectional study an interviewer-administered questionnaire on socio-demographic characteristics and respiratory symptoms was completed and pulmonary function tests were carried out on 100 exposed and 120 non-exposed workers at the cement factory in Mashhad, Iran. The data was statistically analyzed by SPSS 16. Results: The mean of age and work duration in the exposed group was 37.5±6.3 and 10.7±5.4 years compared with the non-exposed group that was 36.1±7.1 and 10.1±5.7 years, respectively. Levels of exposure to inhalable cement dust in the exposed group were 23.13 mg/m3 (higher than national occupational exposure limits for such particles). Among the exposed group, respiratory symptoms as cough (6% vs. 0.8% of the non-exposed) and sputum (7% vs. 0.8% of the nonexposed) were significantly more prevalent (p < 0.05). Forced expiratory flow 25–75% (FEF25–75%) was significantly lower in the exposed workers compared with non-exposed ones (p < 0.05). Also forced expiratory volume in 1 s / forced vital capacity (FEV1/FVC) and FEF25–75% had a reverse correlation with the length of employment (p = 0.000 and p = 0.003, respectively). Conclusions: The findings of this study showed that occupational exposure to cement dust could be a significant factor of respiratory system dysfunction. Strict implementation of a respiratory protection program is recommended in cement industries. Med Pr 2015;66(4):471–47

The knowledge of hand hygiene among the healthcare workers of two teaching hospitals in Mashhad

Introduction: Healthcare-associated infections (HAIs) affect millions of patients worldwide annually. Hand hygiene (HH) has been identified as the single most important factor preventing HAIs. The aim of this study was to determine the knowledge regarding hand hygiene practices amongst health care workers, and identifying the areas of gaps in their knowledge. Methods: This cross-sectional analytic study was conducted in two university hospitals in Mashhad, Iran between May 2014 and September 2015. Data was collected using a translated version of the World Health Organization (WHO) Hand Hygiene Knowledge Questionnaire (revised 2009). The questionnaire contained questions on the participants’ age, gender, profession, year of the course, formal training in HH and 27 multiple choice and "yes” or “no” questions to assess HH knowledge. Data were entered into IBM SPSS Statistics, Version 16. Descriptive statistical methods and also analytical statistical methods include ANOVA and Independent-samples t-test were used in data analyzing. Results: In total, 161 respondents including 32 residents, 92 nurses and 37 nursing assistants enrolled in this study. All study groups had a moderate knowledge of HH. The score of 21% was ≤ 50% (poor) and only 10.6% had a good knowledge score (i.e. the score ≥75%). There was no significant difference in the knowledge level of the participants who had received formal training in HH and those who had not (p=0.68). Also, the mean knowledge score was not associated with age (p=0.12), gender (p=0.84), department (p=0.96) or profession (p=0.43). Conclusion: This study highlights the importance of applying the multimodal training program addressing providers' knowledge regarding hand hygiene, as well as strategies for cognitive, emotional and behavioral methods such as patient engagement in hand-hygiene interventions

Path Planning for Unmanned Underwater Vehicle in 3D Space with Obstacles Using Spline-Imperialist Competitive Algorithm and Optimal Interval Type-2 Fuzzy Logic Controller

Abstract In this research, generation of a short and smooth path in three-dimensional space with obstacles for guiding an Unmanned Underwater Vehicle (UUV) without collision is investigated. This is done by utilizing spline technique, in which the spline control points positions are determined by Imperialist Competitive Algorithm (ICA) in three-dimensional space such that the shortest possible path from the starting point to the target point without colliding with obstacles is achieved. Furthermore, for guiding the UUV in the generated path, an Interval Type-2 Fuzzy Logic Controller (IT2FLC), the coefficients of which are optimized by considering an objective function that includes quadratic terms of the input forces and state error of the system, is used. Selecting such objective function reduces the control error and also the force applied to the UUV, which consequently leads to reduction of energy consumption. Therefore, by using a special method, desired signals of UUV state are obtained from generated three-dimensional optimal path such that tracking these signals by the controller leads to the tracking of this path by UUV. In this paper, the dynamical model of the UUV, entitled as "mUUV-WJ-1" , is derived and its hydrodynamic coefficients are calculated by CFD in order to be used in the simulations. For simulation by the method presented in this study, three environments with different obstacles are intended in order to check the performance of the IT2FLC controller in generating optimal paths for guiding the UUV. In this article, in addition to ICA, Particle Swarm Optimization (PSO) and Artificial Bee Colony (ABC) are also used for generation of the paths and the results are compared with each other. The results show the appropriate performance of ICA rather than ABC and PSO. Moreover, to evaluate the performance of the IT2FLC, optimal Type-1 Fuzzy Logic Controller (T1FLC) and Proportional Integrator Differentiator (PID) controller are designed and applied to the UUV and compared with each other. The simulation results show the superiority of the IT2FLC than the other two controllers

Fuzzy Logic Control of a Ball on Sphere System

The scope of this paper is to present a fuzzy logic control of a class of multi-input multioutput (MIMO) nonlinear systems called “system of ball on a sphere,” such an inherently nonlinear, unstable, and underactuated system, considered truly to be two independent ball and wheel systems around its equilibrium point. In this work, Sugeno method is investigated as a fuzzy controller method, so it works in a good state with optimization and adaptive techniques, which makes it very attractive in control problems, particularly for such nonlinear dynamic systems. The system’s dynamic is described and the equations are illustrated. The outputs are shown in different figures so as to be compared. Finally, these simulation results show the exactness of the controller’s performance

Fuzzy Logic Control of a Ball on Sphere System

The scope of this paper is to present a fuzzy logic control of a class of multi-input multioutput (MIMO) nonlinear systems called &quot;system of ball on a sphere, &quot; such an inherently nonlinear, unstable, and underactuated system, considered truly to be two independent ball and wheel systems around its equilibrium point. In this work, Sugeno method is investigated as a fuzzy controller method, so it works in a good state with optimization and adaptive techniques, which makes it very attractive in control problems, particularly for such nonlinear dynamic systems. The system&apos;s dynamic is described and the equations are illustrated. The outputs are shown in different figures so as to be compared. Finally, these simulation results show the exactness of the controller&apos;s performance

Fasa Registry on Acute Myocardial Infarction (FaRMI): Feasibility Study and Pilot Phase Results.

Myocardial infarction (MI) is the leading cause of death in Iran. Every attempt to improve treatment patterns and patient outcomes needs a surveillance system to both consider the efficacy and safety measures. Fasa Registry on Myocardial Infarction (FaRMI) is the first population-based registry for acute MI in Iran targeted to provide meticulous description of patients' characteristics, to explore the management patterns of these patients, to discover the degree of adherence to the practice guidelines, and to investigate the determinants of poor in-hospital and later outcomes.A diagnosis of acute MI (type I, II and III) was made upon the accepted criteria by the attending cardiologists and types IV and V MI were excluded. Two registrar nurses gathered data on demographics, place of residence and ethnicity, past medical history, risk factors, and the clinical course. Management patterns in the pre-hospital setting, during the hospital stay and at the discharge time were recorded. Routine laboratory results and cardiac biomarkers on three consecutive days were registered.pilot phase included the first 95 patients, 63.5% of whom were men and 31.5% were women. With a mean age of 62.89±13.75 years among participants, the rate of premature MI was 31.8%. ST segment elevation MI accounted for 68.2% cases and inferior wall was the most prevalent region involved followed by anterior and posterior walls.Obtained data on the characteristics of patients suffering an MI event revealed the major determinants of delay in initiation of therapies and contributors of poor outcome. Completeness of data was guaranteed upon involvement of multiple checkpoints and data quality was secured by means of automatic validation processes in addition to weekly physicians' roundups.Execution of FaRMI in the form presented is feasible and it will build up a comprehensive population-based registry for MI in the region