15 research outputs found
Comparison of Isoscalar Vector Meson Production Cross Sections in Proton-Proton Collisions
The reaction was investigated with the TOF
spectrometer, which is an external experiment at the accelerator COSY
(Forschungszentrum J\"ulich, Germany). Total as well as differential cross
sections were determined at an excess energy of (). Using the total cross section of for the
reaction determined here and existing data for the reaction
, the ratio
turns out to be
significantly larger than expected by the Okubo-Zweig-Iizuka (OZI) rule. The
uncertainty of this ratio is considerably smaller than in previous
determinations. The differential distributions show that the
production is still dominated by S-wave production at this excess energy,
however higher partial waves clearly contribute. A comparison of the measured
angular distributions for production to published distributions for
production at shows that the data are consistent with an
identical production mechanism for both vector mesons
Influence of N*-resonances on hyperon production in the channel pp->K+ Lambda p at 2.95, 3.20 and 3.30 GeV/c beam momentum
Hyperon production in the threshold region was studied in the reaction pp ->
K+Lp using the time-of-flight spectrometer COSY-TOF. Exclusive data, covering
the full phase-space, were taken at the three different beam momenta of
p_beam=2.95, 3.20 and 3.30 GeV/c, corresponding to excess energies of
epsilon=204, 285 and 316 MeV, respectively. Total cross-sections were deduced
for the three beam momenta to be 23.9+/-0.8 +/-2.0 ub, 28.4+/-1.3 +/-2.2 ub and
35.0+/-1.3 +/-3.0 ub. Differential observables including Dalitz plots were
obtained. The analysis of the Dalitz plots reveals a strong influence of the
N(1650)-resonance at p_beam=2.95 GeV/c, whereas for the higher momenta an
increasing relative contribution of the N(1710)- and/or of the
N(1720)-resonance was observed. In addition, the pL-final-state interaction
turned out to have a significant influence on the Dalitz plot distribution.Comment: accepted for publication at Physics Letters B; some minor text
changes were done; also the scale of the ordinates of figure 9 has been
changed
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A HIGH-RESOLUTION DETECTION SYSTEM FOR SHORT-LIVED GASEOUS ACTIVITIES
Primary cardioprotection with dexrazoxane in patients with childhood cancer who are expected to receive anthracyclines: recommendations from the International Late Effects of Childhood Cancer Guideline Harmonization Group
Survivors of childhood cancer are at risk of anthracycline-induced cardiotoxicity, which might be prevented by dexrazoxane. However, concerns exist about the safety of dexrazoxane, and little guidance is available on its use in children. To facilitate global consensus, a working group within the International Late Effects of Childhood Cancer Guideline Harmonization Group reviewed the existing literature and used evidence-based methodology to develop a guideline for dexrazoxane administration in children with cancer who are expected to receive anthracyclines. Recommendations were made in consideration of evidence supporting the balance of potential benefits and harms, and clinical judgement by the expert panel. Given the dose-dependent risk of anthracycline-induced cardiotoxicity, we concluded that the benefits of dexrazoxane probably outweigh the risk of subsequent neoplasms when the cumulative doxorubicin or equivalent dose is at least 250 mg/m(2) (moderate recommendation). No recommendation could be formulated for cumulative doxorubicin or equivalent doses of lower than 250 mg/m(2), due to insufficient evidence to determine whether the risk of cardiotoxicity outweighs the possible risk of subsequent neoplasms. Further research is encouraged to determine the long-term efficacy and safety of dexrazoxane in children with cancer